Input sequence

Protein name Probable E3 ubiquitin-protein ligase HERC2
Organism Drosophila melanogaster Length 4912
Disorder content 18.8% ProS content 6.2%
IDEAL NA UniProt Q9VR91

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 4912 1-67 68-167 168-187 188-191 192-259 260-299 300-379 380-385 386-426 427-450 451-455 456-470 471-520 521-530 531-987 988-993 994-1013 1014-1019 1020-1058 1059-1064 1065-1078 1079-1107 1108-1127 1128-1188 1189-1194 1195-1275 1276-1285 1286-1368 1369-1380 1381-1436 1437-1469 1470-1638 1639-1678 1679-1776 1777-1780 1781-1824 1825-1828 1829-1885 1886-1894 1895-1906 1907-1918 1919-1988 1989-2013 2014-2037 2038-2041 2042-2062 2063-2070 2071-2379 2380-2414 2415-2459 2460-2517 2518-2559 2560-2618 2619-2699 2700-2707 2708-2710 2711-2945 2946-2981 2982-3387 3388-3398 3399-3434 3435-3579 3580-3624 3625-3662 3663-3833 3834-3840 3841-3894 3895-3908 3909-3956 3957-4010 4011-4413 4414-4436 4437-4498 4499-4506 4507-4514 4515-4525 4526-4891 4892-4912 68-167 192-259 300-379 386-426 451-455 471-520 531-987 994-1013 1059-1064 1079-1107 1128-1188 1195-1275 1286-1368 1381-1436 1470-1638 1679-1776 1781-1824 1829-1885 1895-1906 1919-1988 2014-2037 2042-2062 2071-2379 2415-2459 2518-2559 2619-2699 2711-2945 2982-3387 3399-3434 3580-3624 3663-3833 3841-3894 3909-3956 4011-4413 4437-4498 4507-4514 4526-4891 1-67 168-187 260-299 380-385 427-450 456-470 521-530 1020-1058 1065-1078 1108-1127 1276-1285 1369-1380 1437-1469 1639-1678 1886-1894 1907-1918 1989-2013 2038-2041 2063-2070 2380-2414 2460-2517 2560-2618 2708-2710 2946-2981 3388-3398 3435-3579 3625-3662 3895-3908 3957-4010 4414-4436 4499-4506 4515-4525 4892-4912 1-5 32-38 44-48 168-174 260-263 427-450 456-458 1035-1058 1065-1068 1108-1114 1369-1373 1437-1447 1459-1469 1639-1642 1650-1655 1676-1678 2003-2007 2038-2041 2515-2517 2560-2562 2946-2971 3435-3438 3444-3450 3549-3561 3567-3579 3637-3645 3657-3662 3957-3961 3975-4010 4414-4436 4499-4506 4892-4894 4904-4912 4050-4415 2987-3350 574-903 4600-4873 1923-1987 2624-2698 4050-4415 2987-3350 538-903 638-853 4531-4876 1923-1987 2633-2698 2799-2933 2509-2558 4614-4873 2624-2702 1928-1989 4365-4413 3302-3349 3144-3194 3092-3140 4155-4203 4207-4248 3250-3298 687-737 4313-4360 4051-4094 636-683 740-787 1290-1364 1928-1990 3037-3088 3091-3140 3143-3194 3197-3246 3249-3298 4154-4203 4260-4309 4364-4413 4576-4878 4481-4874 2988-3303 4051-4366 534-846 2624-2698 1919-1988 2800-2933 3664-3755 2503-2557 1285-1361 574-899 1287-1363 2506-2560 2748-2935 2972-3354 3644-3755 4035-4417 4508-4876 5-66 170-191 253-259 261-287 333-349 408-422 452-465 522-530 1110-1124 1130-1144 1151-1162 1213-1224 1239-1253 1269-1283 1420-1431 1460-1472 1612-1628 1632-1645 1671-1690 1762-1786 1879-1897 2120-2133 2281-2292 2343-2358 2591-2604 3204-3215 3527-3543 3549-3563 3793-3811 3888-3910 3955-3961 3974-3992 4107-4121 4267-4281 4418-4431 3kciA(1-366) 3e-159 78.96% 3kciA(1-364) 3e-121 57.69% 4l1mA(27-358) 1e-69 43.07% 1nd7A(91-370) 9e-26 28.27% 3dkmA(11-74) 2e-15 55.38% 2jngA(2-73) 4e-07 41.33% 3kciA(1-366) 1e-54 78.96% 3kciA(1-364) 5e-43 57.69% 4l1mA(5-358) 4e-25 39.14% 4x33B(4-203) 7e-18 18.06% 1c4zA(12-350) 7e-24 20.11% 3dkmA(11-74) 3e-12 53.85% 2jufA(1-63) 7e-12 37.88% 1jhjA(21-159) 2e-05 17.86% 2ekkA(5-47) 7e-05 34.0% PF00632(29-288) 4e-43 38.17% PF11515(1-78) 6e-29 72.15% PF06701(1-62) 2e-14 51.61% PF00415(1-49) 7e-09 53.06% PF00415(1-48) 1e-07 52.08% PF00415(1-49) 2e-06 50.98% PF00415(1-49) 3e-06 44.9% PF00415(1-49) 3e-06 42.86% PF00415(1-42) 6e-06 50.0% PF00415(1-49) 6e-05 42.86% PF00415(1-49) 0.0001 50.98% PF00415(1-48) 0.0001 39.58% PF00415(3-47) 0.0007 46.67% PF00415 0.00077 23.4% PF00415 3.2e-08 37.9% PF00173 4.7e-20 77.2% PF06701 3.8e-39 140.7% PF00415 0.00055 23.9% PF00415 1.1e-07 36.1% PF00415 5e-07 34.0% PF00415 8e-07 33.3% PF00415 1.6e-05 29.0% PF00415 1.7e-06 32.1% PF00415 1.8e-06 32.1% PF00415 6.9e-07 33.5% PF00632 8.6e-54 189.3% 1nd7A(4-371) 9e-72 23.81% 1a12A(68-399) 9e-63 25.37% 1a12A(68-399) 3e-56 24.78% 1a12A(67-399) 4e-44 20.12% 2jngA1(1-72) 4e-26 41.33% 2dk3A1(3-71) 1e-15 50.0% 1jhjA(15-159) 4e-14 21.77% 1nt0A2(20-107) 4e-08 19.57% 2cpwA1(2-51) 1e-07 16.36% 1awpA(1-77) 4e-06 19.48% b.69.5 1.5e-61 209.1% d.120.1 8.8e-05 15.1% a.5.2 0.0004 16.6% b.18.1 9.3e-22 72.0% b.69.5 1.9e-96 328.3% b.23.1 1.7e-06 20.4% b.69.5 4.7e-98 333.8% d.148.1 1.3e-90 271.7%

Sequence

MFNRQASGGAGSSGQGAGSSQTASAAPVSAGVGVGGGGGASGAAAGAGSAAGSGSGSGSG
SAAPPSHSPDLYLRPLPFLDAKWLRADLIASLRNAADGAVLWNHLIQDCELVSSPTAPLL
NARGQLSYLGDDGKHYCGAQQLKCSCCQPEYCGPLSACNCDGCRPLDSDTAIKKLTTQAA
AQQAAHLSQATDMVLSGWLWSQPPSQQARLDCQRSMISELQELALRAAGNCLSAQHLRQQ
LFIYERYFVALKRERERERKSTTSAQAVASVTTANTTIAATTANAAVESQPAEQQAEHGA
LGLARVATHAALNFSFAFLRRAWRSGEDTEMCSELLSEALASLQELPEATLFEAAVVSSL
WLEVMERSIKFLRLVALGDPMGNRCTAPLNDRHTALCLLLELGVQKGTLAATLECVVLLL
LLWEKDRAGNDNRDMPRKTGAPLQRILLRYQKIGATAKGGGIAGGEPAPVASATETFLRF
LSLPKSSAAIVDLRRAAVVIISHLDRMVQPLMPRCLLRGGQATAASSSSAPQQRIYALGW
PSLSKDQQGFSAEPTLSWSGESAGVPTLSCRFQIKQVACCETQMLILSQEGKLYTWRLAK
PEAEPLPMEEVAHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHARAVPT
KIAALEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDH
MVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVESLPRVQRVFAG
SQFSVALSSEGQLYTWGKATCLGHQLVERSVQGCSVPRLVSSLQHKRIVDVAVSVAHCLA
LSSSGEVFGWGRNDSQQICPASVSSEPLLRTPILVSLPTFPASGIACTSAQSLVWTQSSH
QGVPRRAPFVVDLGEPTFRLLDQLLGMCSSQDNRQTPNQESECIAVACLNLFRLQLLALI
ANGVEPRQVGLASGSRLLCSLKTRILGLAGGSQVLRTIQVAAQQALQDGWSVLLPTAAER
AQTLTSLLPSEPGQASSAGHRFMTDLLVSSLMAEGGLESALQHAIRLESSSCSADCGDGV
HLPLLQLITRLLSNNAALSQTRLSPTLGKQQEKEEEEREQQHQEPSTSPSLSLLHRFQRL
LLSHIHQAQPEEETTGAEALLLQYMHALIPACVATLQKAHELALQCREPGENSFGQMVGH
LGRVLQADISDALLNELLVGLLLLKRDRPQCLGGLRWARLFLPLLRVLDRLNRALGEGEL
RDGDDMGWPGIICRGGPKGGPPPADPETHYVRRADMENLLLDGSRCIILAGYVCDLSGYN
CESETLRSVLDSGLGKDLTAEMSSQVHRTAMEHILEHHKLGKYMVQASTEEKSSAPGPSR
LTHFSSECALAQLLGLVANLMCSGPALQPAELQCRQLDKSSLLSGGLQLLQPSNPFDEEK
GEARSSHSCHSTAGNTPTELPPPLPMQQQLAPGRGKSQLQLRADAFISGLAEARVSEPPV
AAWLALTERYCKAHNLMWHQEFATEHPVQELERLLSAVLIRHQYLGGLVLNALETEVPPP
RQLGEIIRLVHQAKWSVVRTRQQLNRSYKEVCAPILERLRFLLYEVRPAISPQQRGLRRL
PILQRPPRFKMLVRRLLQELRSSRQPAKPEDLLNASIQQEQEKKPQSMPKQELEEQEEEE
TLLRRLNERQIHGEGELDPALMQDIVDFALQDSCDVETARRAMYCQMQRYQLRLAGLQIV
QQLLELHGLLDAAQYSLLNGFLGLHLKSTSSGGGSTGSGSSLHVLGQLNMISAYQKARLL
LAQSRVLDWAVRELRRLVNQEQQGHARGKDSTNLGTYVLLKRLPRARFLLSVFGLLAKEL
GPNELGFLINSGLLGTVLGLLAQTGGEGATGGQVHGELSILYEDSVLKQKSSKAQLSGPD
LAKLMKIGTRIVRGADWKWGDQDGNPPGEGRIISEVGEDGWVRVEWYTGATNSYRMGKEG
QYDLQLADSALNVASPTEPEREDVSGSEASPTSDSHPSKLLRHCAAKLLQILAVGTGLHG
AQLDKDALRGMTSMFRTIIYPKPSMSNISYALGWLNLGFIRAISGDCPRLCLELSTPGWL
SHYLSLLEQPAGNEAGVYRQLHCLRLLQLILAQWGAEEEPRMPALVHQLFATLGRIALHC
PGDASLLPTAEGKARVLLTASHSGSVAEELVALLRRLHTLPSWNPVINSFLAQKLCVAAE
LLAEQSHSTALDSEQVFVLGVLGAMGGHDLRPRVGLHCFHEGSHMVIASFTPKGRCLLAP
GGVGSGVGFVKVQLPAVMPHLDHTVFSLSRLPMNEMLLNAWTVLLYGPAPELRELPSSAD
GRLDLALLRAQQLQMAVLHTNGVLYRHQVALRRILKQRAPGSIYASPDEPDRSDAESQQP
GEQDQQLSSGSGQEPQLLIQCILLRATQASPVKACYSYMDLATAALNCIQSLATQAHQEL
SEGGGVPPNGRALSSPPQPTMVHGVPVYNVARKEQKPSEQVEQKSKWPAAATDAQLIGQI
MEMGFTRRTVELALKQLSLQAEIMPTPEQIVQWILEHPDVCANTIEEDTLPLASSASSHD
PEADSDNECPSSNSTTSSSTSSDTVEGQPMAVSGPAPPVKFESRKDFQTADLYALYVRGL
VRPGMTVRCCRDFEEIKQGDMGTVLIVDTEGLHDLNVQVDWRNHGSTYWVCFVHIELVEA
AQTHHQPRPPPIAVGARVRLRTSSLRYGMLCPLRLGRSQGSSAIGVVSSVRSKQLTVDFP
DQPAWQGHINEVELVASQPTSATLPSLGDSCSQMPPSDLIEDWSRCIRSLTVSSNEAAAK
HLLNGSNQPWQSCSSGPCRHWIRLELHDRILVHSLTLKVSPEDHSHMPSLLEIRVGDCVD
SLKEYTWIPVPAGASRVLLMQQVPTYYPWVEVVVKQCQNNGIQCKIHGIKFVGRRQQPDL
QHILANAQFLASEYSAGVGPGSTAGAGAVSTSHEEAAAAPEQDLPCTVMVWGLNDKEQLG
GLKGSKVKVPTFSQTISRLRPIHIAGGSKSLFIVSQDGKVYACGEGTNGRLGLGVTHNVP
LPHQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVE
ALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVV
QVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGIGVVQIECGA
QFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRGRRVIHVAVGALHCLAVTD
AGQVYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVFVNRVACGSSHSIAWGLPNASSDEE
KRGPVPFSSTRDPLGGSSLGIYEAETMQTLKQEAKPLNQSSLSESLALETPAARQAALGH
VLRAMSILQARQLIVAALTSHSKVNFKERGAVGGEEDHLIGGPIMGAPLQLAETIAQGGG
EAPADATDAGLQEHSPEAAVDALTGGMSGGANTLPPLSAGPLSAFQSLTGSLSMSGSLSS
SALPQHKHSRMSASAMSVMAATMTQQEEMLSHISHCHGLDDFGGLLGEPEAKSLVELLKL
AVCGRCGPPSTSQTIADTLISLGAGTPAVAAMLLETCITELEDLCTSRHCLGKLPKPVMQ
ESSHPYVDNVNVTGVVRIPGAEMLRLEFDSQCSTEKRNDPLVIMDGTGRVLAMRSGREFA
HWAPEIRVLGDELRWKFSSDSSVNGWGWRFWVHAIMPAATLGESGSDRAVLSQPSMALVM
SLLDSRLAPRQPSVLLRLASALAACSQLGALTTAQRIWSLRKLHAVLLLEQAPRPQDPSL
STLLQPLIPELLRQYEYEEPQVRGGIHLMHSDYFKTLAALACDMQLDAALPATSSSSSSS
AAPGAISSTGDVHKWAWFKRYCIAVRVAQSLIRRTELPRAFCLEVRKKFAEMLPSSSSNS
NANPGCQSPGASMLNSTTSLSSSTVSNVSPPPGITGEQPDLHCHAHQLESTSTLLHEDHT
LFQAPHDAQLLQWLNRRPDDWALSWGGASTIYGWGHNHRGQLGGLEGSRIKTPTPCEALS
LLRPVQLAGGEQSLFAVTPDGKLFATGYGSGGRLGVGGSDSWAIPTLLGSLQHVFVKKVA
VNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNRMSYDRPKLVEHLNGMSVADIACGSAHS
AAITASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDD
DNVWSWGDGDYGKLGRGGSDGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGK
GDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGEVYTWGDNDEGQLGD
GTVTAIQRPRLVAALQGKHIVKVTCGSAHTLALSTSQLSERLRPLPNPPLEYDLVRDLAP
EALHARLILLHHFSELVCPCLAMLPISGDLSLGALKDVLVYNIKEAAFRKVIQTTMVRDK
QHGPVIELNRIQVKRSRNRCNGLAGIDGMKSVFGQMVQKLPLLTQEALALPHRVWKVKFV
GESVDDCGGGYSESIAEMCDELQNGSVPLLINTPNGRGEAGANRDCFLLDPTLSSVLQMN
MFRFLGVLMGIAVRTGSPLSINLAEPVWRQLTGEVLRPTDLTEVDRDYVAGLLCIRNMDD
DPKLFTALELPFSTSSARGHEVPLSTRYTHISPRNRAEYVRLALGFRLHEFDEQVKAVRD
GMSKVIPVPLLSLFSAAELQAMVCGSPDIPLGLLKSVATYKGFDPSSALVTWFWEVMEEF
TNQERSLFLRFVWGRTRLPRTIADFRGRDFVLQVLEKNPPDHFLPESYTCFFLLKMPRYS
CKAVLLEKLKYAIHFCKSIDTDEYARVAMGEPTEATGSEDNSDLESVASHEG

Region:1-4912
Length:4912aa
Label:Full sequence
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