Input sequence

Protein name E3 ubiquitin-protein ligase HECW2
Organism Homo sapiens Length 1572
Disorder content 52.2% ProS content 15.0%
IDEAL NA UniProt Q9P2P5

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 1572 1-21 22-26 27-31 32-37 38-58 59-166 167-178 179-322 323-824 825-841 842-1087 1088-1169 1170-1183 1184-1572 22-26 32-37 59-166 179-322 825-841 1088-1169 1184-1572 1-21 27-31 38-58 167-178 323-824 842-1087 1170-1183 7-21 27-31 38-58 323-325 384-389 413-419 436-443 450-462 484-490 497-501 522-526 555-560 565-579 599-602 806-824 845-875 929-933 942-947 953-966 986-1018 1176-1183 1191-1566 57-162 915-1022 809-841 1191-1566 57-162 915-1022 808-843 986-1019 192-322 1268-1571 187-282 809-838 987-1016 1267-1572 1192-1566 192-325 806-846 970-1019 192-328 798-847 976-1018 1213-1566 165-175 400-410 542-556 744-760 765-780 2xbbA(1-374) 4e-110 50.4% 2lfeA(1-106) 7e-60 100.0% 3l4hA(1-106) 1e-41 74.07% 2dmvA(8-40) 7e-09 63.64% 2xbbA(1-374) 2e-52 50.13% 2lfeA(1-106) 8e-39 100.0% 3l4hA(1-106) 2e-29 74.07% 2dmvA(7-42) 4e-12 58.33% 2dmvA(7-40) 2e-06 41.18% 2ep6A(20-130) 6e-05 18.94% PF00632(1-296) 2e-66 46.1% PF00168 4.9e-10 44.0% PF00397 3.1e-14 57.9% PF00397 5.7e-10 43.7% PF00632 1.3e-174 590.7% 1nd7A(3-373) 4e-107 48.67% 2ep6A1(13-126) 2e-10 17.78% 1jmqA(6-46) 1e-08 36.59% 2pstX1(2-54) 2e-06 14.55% b.7.1 1.5e-11 36.5% b.72.1 2.1e-11 42.7% b.72.1 1.2e-12 44.5% d.148.1 9.3e-128 383.5%

Sequence

MASSAREHLLFVRRRNPQMRYTLSPENLQSLAAQSSMPENMTLQRANSDTDLVTSESRSS
LTASMYEYTLGQAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQ
IVWRIEPGPYFMEPEIKICFKYYHGISGALRATTPCITVKNPAVMMGAEGMEGGASGNLH
SRKLVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTT
NPIWHREKYSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAIGDQMLS
YNLGRRLPADHVSGYLQFKVEVTSSVHEDASPEAVGTILGVNSVNGDLGSPSDDEDMPGS
HHDSQVCSNGPVSEDSAADGTPKHSFRTSSTLEIDTEELTSTSSRTSPPRGRQDSLNDYL
DAIEHNGHSRPGTATCSERSMGASPKLRSSFPTDTRLNAMLHIDSDEEDHEFQQDLGYPS
SLEEEGGLIMFSRASRADDGSLTSQTKLEDNPVENEEASTHEAASFEDKPENLPELAESS
LPAGPAPEEGEGGPEPQPSADQGSAELCGSQEVDQPTSGADTGTSDASGGSRRAVSETES
LDQGSEPSQVSSETEPSDPARTESVSEASTRPEGESDLECADSSCNESVTTQLSSVDTRC
SSLESARFPETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTAGSLPVVQVPSGEDEGP
GAESATVPDQEELGEVWQRRGSLEGAAAAAESPPQEEGSAGEAQGTCEGATAQEEGATGG
SQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTA
PPAPQVLQRSNSIQQMEQLNRRYQSIRRTMTNERPEENTNAIDGAGEEADFHQASADFRR
ENILPHSTSRSRITLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRD
THHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPL
QSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRPQYQDMVPVA
YNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLS
LFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNF
YRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSG
PSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIH
QYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVF
GQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSV
FDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFV
TGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLL
TAVEETSTFGLE

Region:1-1572
Length:1572aa
Label:Full sequence
Reset:click