Input sequence

Protein name eIF-2-alpha kinase GCN2
Organism Homo sapiens Length 1649
Disorder content 18.0% ProS content 7.2%
IDEAL NA UniProt Q9P2K8

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 1649 1-16 17-206 207-259 260-542 543-580 581-658 659-793 794-878 879-898 899-1337 1338-1342 1343-1363 1364-1367 1368-1495 1496-1530 1531-1649 17-206 260-542 581-658 794-878 899-1337 1343-1363 1368-1495 1531-1649 1-16 207-259 543-580 659-793 879-898 1496-1530 14-16 231-259 543-554 569-578 659-661 692-715 722-737 743-750 895-898 1496-1504 1527-1649 18-144 798-1008 1055-1489 584-657 335-549 796-1008 1527-1649 584-659 18-144 296-539 1061-1490 797-997 305-450 21-134 18-134 315-539 590-1001 18-144 1069-1382 796-1008 330-545 587-659 1394-1499 1348-1427 16-145 332-552 565-1028 1061-1389 1393-1488 2-17 161-174 178-200 484-495 732-740 1174-1185 1245-1257 1298-1313 145-206 4otnA(1-123) 7e-60 94.31% 1ukxA(10-136) 1e-59 88.19% 1zy4A(84-263) 2e-40 45.28% 4g84A(10-430) 3e-28 24.72% 4x7kA(3-76) 6e-14 45.95% 2j51A(48-282) 2e-16 28.03% 1zy4A(82-263) 5e-55 43.93% 4otnA(1-123) 4e-44 94.31% 4x7kA(3-78) 3e-19 44.74% 1ukxA(10-136) 4e-37 88.19% 1s9iA(27-279) 4e-26 21.15% 4g84A(16-431) 4e-18 23.09% PF00069(72-254) 1e-23 38.16% PF00069(10-148) 1e-13 31.51% PF05773(4-112) 6e-06 33.9% PF05773 1e-33 122.6% PF00069 1.6e-10 32.4% PF00069 8.4e-53 186.0% 1ukxA(10-136) 2e-36 88.19% 1usyA(10-274) 4e-24 15.56% 1nw1A(168-363) 8e-20 10.09% 1nw1A(129-361) 2e-14 9.01% 1ia8A(4-74) 8e-10 28.38% 1evkA1(5-109) 3e-11 16.98% 1c0aA3(271-345) 0.0001 10.0% d.20.1 6e-38 133.2% d.144.1 6.4e-34 110.3% d.144.1 1.7e-65 204.3% d.104.1 1.9e-38 133.9% c.51.1 1.1e-05 20.3%

Sequence

MAGGRGAPGRGRDEPPESYPQRQDHELQALEAIYGADFQDLRPDACGPVKEPPEINLVLY
PQGLTGEEVYVKVDLRVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGE
VMIFELAYHVQSFLSEHNKPPPKSFHEEMLERRAQEEQQRLLEAKRKEEQEQREILHEIQ
RRKEEIKEEKKRKEMAKQERLEIASLSNQDHTSKKDPGGHRTAAILHGGSPDFVGNGKHR
ANSSGRSRRERQYSVCNSEDSPGSCEILYFNMGSPDQLMVHKGKCIGSDEQLGKLVYNAL
ETATGGFVLLYEWVLQWQKKMGPFLTSQEKEKIDKCKKQIQGTETEFNSLVKLSHPNVVR
YLAMNLKEQDDSIVVDILVEHISGVSLAAHLSHSGPIPVHQLRRYTAQLLSGLDYLHSNS
VVHKVLSASNVLVDAEGTVKITDYSISKRLADICKEDVFEQTRVRFSDNALPYKTGKKGD
VWRLGLLLLSLSQGQECGEYPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFIN
PQPKMPLVEQSPEDSEGQDYVETVIPSNRLPSAAFFSETQRQFSRYFIEFEELQLLGKGA
FGAVIKVQNKLDGCCYAVKRIPINPASRQFRRIKGEVTLLSRLHHENIVRYYNAWIERHE
RPAGPGTPPPDSGPLAKDDRAARGQPASDTDGLDSVEAAAPPPILSSSVEWSTSGERSAS
ARFPATGPGSSDDEDDDEDEHGGVFSQSFLPASDSESDIIFDNEDENSKSQNQDEDCNEK
NGCHESEPSVTTEAVHYLYIQMEYCEKSTLRDTIDQGLYRDTVRLWRLFREILDGLAYIH
EKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFSADSKQDDQTGDLIKSDPSGHLTG
MVGTALYVSPEVQGSTKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSP
KFPEDFDDGEHAKQKSVISWLLNHDPAKRPTATELLKSELLPPPQMEESELHEVLHHTLT
NVDGKAYRTMMAQIFSQRISPAIDYTYDSDILKGNFSIRTAKMQQHVCETIIRIFKRHGA
VQLCTPLLLPRNRQIYEHNEAALFMDHSGMLVMLPFDLRIPFARYVARNNILNLKRYCIE
RVFRPRKLDRFHPKELLECAFDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYL
NHTMLLKAILLHCGIPEDKLSQVYIILYDAVTEKLTRREVEAKFCNLSLSSNSLCRLYKF
IEQKGDLQDLMPTINSLIKQKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLGLVYK
VQQHNGIIFQFVAFIKRRQRAVPEILAAGGRYDLLIPQFRGPQALGPVPTAIGVSIAIDK
ISAAVLNMEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMYDWSQSQEELQ
EYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKLRTKVTDERNG
REASDNLAVQNLKGSFSNASGLFEIHGATVVPIVSVLAPEKLSASTRRRYETQVQTRLQT
SLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTTVKQLLSRLPKQRYLKLVC
DEIYNIKVEKKVSVLFLYSYRDDYYRILF

Region:1-1649
Length:1649aa
Label:Full sequence
Reset:click