Input sequence

Protein name Inhibitor of Bruton tyrosine kinase
Organism Homo sapiens Length 1353
Disorder content 27.1% ProS content 3.6%
IDEAL NA UniProt Q9P2D0

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 1353 1-9 10-470 471-491 492-963 964-1299 1300-1353 10-470 492-963 1300-1353 1-9 471-491 964-1299 5-9 471-491 964-970 1284-1299 114-357 744-899 21-135 27-125 767-866 543-638 144-420 85-176 871-933 769-864 565-641 51-83 85-117 554-688 757-871 132-302 52-129 745-867 506-640 233-387 20-140 127-460 536-642 742-870 202-212 466-476 699-709 976-989 3kciA(133-366) 7e-14 29.27% 3hqiA(136-290) 7e-10 28.4% 2bkkB(7-118) 8e-09 29.91% 3deoA(54-149) 7e-19 31.31% 4eozA(21-114) 1e-15 26.0% 3fkcA(5-85) 5e-11 27.27% 4x33B(3-283) 1e-14 18.06% 1d9sA(11-101) 0.0007 14.13% 4hs2A(2-64) 0.0001 30.16% PF00651(10-99) 9e-11 39.18% PF00651(10-73) 4e-07 38.96% PF00023 0.00013 26.0% PF00023 8.5e-07 33.2% PF00651 1.3e-07 35.9% PF00651 1.5e-15 62.3% 1a12A(229-397) 2e-31 25.58% 1s70B(199-275) 2e-14 32.05% 1buoA(7-117) 1e-11 21.95% 1vz6A(194-324) 2e-08 9.72% 1jtdB(30-150) 0.0001 17.95% d.211.1 1.1e-21 67.6% b.69.5 5.5e-56 190.0% d.42.1 4e-16 58.9% d.42.1 1.4e-20 74.8%

Sequence

MSSPMPDCTSKCRSLKHALDVLSVVTKGSENQIKAFLSSHCYNAATIKDVFGRNALHLVS
SCGKKGVLDWLIQKGVDLLVKDKESGWTALHRSIFYGHIDCVWSLLKHGVSLYIQDKEGL
SALDLVMKDRPTHVVFKNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIK
QVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDH
TVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWT
REAVYTMGLNGGQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGATVCVTTRGD
IYLLADYQCKKMASKQLNLKKVLVSGGHMEYKVDPEHLKENGGQKICILAMDGAGRVFCW
RSVNSSLKQCRWAYPRQVFISDIALNRNEILFVTQDGEGFRGRWFEEKRKSSEKKEILSN
LHNSSSDVSYVSDINSVYERIRLEKLTFAHRAVSVSTDPSGCNFAILQSDPKTSLYEIPA
VSSSSFFEEFGKLLREADEMDSIHDVTFQVGNRLFPAHKYILAVHSDFFQKLFLSDGNTS
EFTDIYQKDEDSAGCHLFVVEKVHPDMFEYLLQFIYTDTCDFLTHGFKPRIHLNKNPEEY
QGTLNSHLNKVNFHEDDNQKSAFEVYKSNQAQTVSERQKSKPKSCKKGKNIREDDPVRML
QTVAKKFDFSNLSSRLDGVRFENEKINVIAKNTGNKLKLSQKKCSFLCDVTMKSVDGKEF
PCHKCVLCARLEYFHSMLSSSWIEASSCAALEMPIHSDILKVILDYLYTDEAVVIKESQN
VDFICSVLVVADQLLITRLKEICEVALTEKLTLKNAAMLLEFAAMYSAKQLKLSCLQFIG
LNMAALLEARSLDVLSDGVLKDLSEFYRKMIPAMDRRVITPYQDGPDISYLEVEDGDIFL
KEEINMEQNHSETMFKKAKTKAKKKPRKRSDSSGGYNLSDIIQSPSSTGLLKSGKTNSVE
SLPELLTSDSEGSYAGVGSPRDLQSPDFTTGFHSDKIEAKVKPYVNGTSPVYSREDLKPW
EKSPILKISAPQPIPSNRIDTTSSASWVAGSFSPVSPPVVDLRTIMEIEESRQKCGATPK
SHLGKTVSHGVKLSQKQRKMIALTTKENNSGMNSMETVLFTPSKAPKPVNAWASSLHSVS
SKSFRDFLLEEKKSVTSHSSGDHVKKVSFKGIENSQAPKIVRCSTHGTPGPEGNHISDLP
LLDSPNPWLSSSVTAPSMVAPVTFASIVEEELQQEAALIRSREKPLALIQIEEHAIQDLL
VFYEAFGNPEEFVIVERTPQGPLAVPMWNKHGC

Region:1-1353
Length:1353aa
Label:Full sequence
Reset:click