Input sequence

Protein name Rho guanine nucleotide exchange factor 12
Organism Homo sapiens Length 1544
Disorder content 52.9% ProS content 17.9%
IDEAL NA UniProt Q9NZN5

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 1544 1-65 66-147 148-198 199-259 260-367 368-566 567-766 767-1066 1067-1078 1079-1133 1134-1495 1496-1505 1506-1511 1512-1531 1532-1544 66-147 199-259 368-566 767-1066 1079-1133 1496-1505 1512-1531 1-65 148-198 260-367 567-766 1067-1078 1134-1495 1506-1511 1532-1544 7-45 188-198 268-277 290-295 304-310 316-333 348-367 567-577 584-588 597-632 727-736 754-766 1072-1078 1134-1140 1223-1237 1246-1268 1375-1387 1407-1421 1478-1481 1506-1511 766-1138 67-151 370-558 766-1138 370-558 66-151 372-558 792-975 72-145 791-976 370-558 766-999 996-1133 71-155 55-165 370-559 766-998 1020-1133 49-64 213-225 583-596 663-676 721-733 1256-1269 1361-1371 199-259 493-520 957-984 1txdA(1-352) 0.0 94.1% 2omjA(5-89) 3e-42 100.0% 1iapA(1-189) 1e-35 41.58% 1txdA(1-352) 2e-93 93.83% 1iapA(1-189) 5e-50 41.58% 2omjA(4-89) 2e-32 98.84% PF09128(5-188) 4e-44 52.94% PF00621(2-178) 2e-29 37.3% PF00595 1.5e-12 52.3% PF00621 2.2e-19 75.0% 1iapA(1-189) 2e-67 41.58% 1txdA1(1-234) 2e-54 99.57% 1xcgA2(1-126) 4e-27 48.92% 1vaeA(17-103) 5e-21 26.44% b.36.1 2e-25 79.6% a.91.1 2.5e-72 229.0% a.87.1 2.1e-64 224.4% b.55.1 4.5e-42 132.9%

Sequence

MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDAS
RPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR
IFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGY
LPANSMSSVASGASFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQ
VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK
PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTS
GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLK
QLLVQQLGLTEKSVQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTG
DIATCYSPRTSTESFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEH
FFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ
PMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQ
SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS

Region:1-1544
Length:1544aa
Label:Full sequence
Reset:click