Input sequence

Protein name Otoferlin
Organism Homo sapiens Length 1997
Disorder content 17.0% ProS content 9.0%
IDEAL NA UniProt Q9HC10

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 1997 1-132 133-247 248-385 386-393 394-395 396-581 582-594 595-646 647-692 693-1243 1244-1324 1325-1330 1331-1342 1343-1346 1347-1401 1402-1440 1441-1445 1446-1947 1948-1952 1953-1966 1967-1968 1969-1994 1995-1997 1-132 248-385 396-581 595-646 693-1243 1325-1330 1343-1346 1402-1440 1446-1947 1953-1966 1969-1994 133-247 394-395 582-594 647-692 1244-1324 1331-1342 1347-1401 1441-1445 1948-1952 1967-1968 1995-1997 133-157 164-173 179-186 394-395 593-594 682-692 1244-1257 1265-1299 1331-1342 1347-1397 1948-1952 1967-1968 1995-1997 1-124 1494-1574 961-1062 1-124 1493-1581 420-520 254-359 961-1094 1117-1173 842-918 339-406 1494-1577 962-1050 453-504 256-338 339-410 419-514 842-919 962-1052 1494-1577 1494-1605 953-1099 1745-1864 249-356 434-527 18-124 239-385 396-541 940-1096 1100-1224 1473-1612 1699-1866 151-164 608-619 1192-1203 1242-1258 1291-1323 1370-1397 1436-1447 1908-1920 1965-1983 795-822 1969-1991 3l9bA(3-126) 2e-59 91.13% 3pfqA(72-157) 7e-06 33.72% 3jzyA(3-94) 4e-05 27.45% 3l9bA(3-126) 2e-37 91.13% 2ep6A(14-99) 5e-16 31.46% 4iqhA(6-95) 2e-09 21.15% 4iqhA(3-110) 2e-06 17.27% 3jzyA(3-121) 3e-12 23.88% 3fc3A(15-69) 0.0004 31.58% PF08150(1-75) 2e-23 62.34% PF08151(1-68) 7e-17 55.88% PF00168(1-85) 7e-09 35.29% PF00168(1-83) 3e-08 32.98% PF00168(21-74) 0.0005 40.0% PF00168 5.3e-12 50.5% PF08151 4.5e-53 186.9% PF00168 6.9e-18 70.0% PF08150 5.2e-60 210.0% PF00168 3.8e-16 64.3% PF00168 1.3e-21 82.4% 1a25A(17-132) 3e-14 23.28% 1wfjA(3-133) 1e-10 15.54% 1bdyA(11-105) 0.0004 6.67% 1n05A(10-138) 8e-12 7.75% 2cjsA1(1-91) 2e-09 22.34% b.7.1 5e-10 31.6% b.7.1 2.3e-18 58.2% b.7.1 3.6e-23 73.5% b.7.1 4.2e-20 63.7% b.7.1 2.6e-11 38.8% b.7.1 1e-29 94.3% b.7.1 2.1e-19 67.3%

Sequence

MALLIHLKTVSELRGRGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNE
MLEIQVFNYSKVFSNKLIGTFRMVLQKVVEESHVEVTDTLIDDNNAIIKTSLCVEVRYQA
TDGTVGSWDDGDFLGDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFRRAGRSVFSAMK
LGKNRSHKEEPQRPDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKP
DIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEY
FVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILS
DPDDISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFY
VKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNE
QVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMY
GSTRNYTLLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSNPELTSSTEVQVEQATPIS
ESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNEVDGLSRPQRPRPRKEPG
DEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHLPYLERKPCIYIKSWWPD
QRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYPERRLRGVLEELSCGCCRFLSLADK
DQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLAD
EPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSIVEEETGKDCAKVKTLFLKLPGKRGFG
SAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQAF
QLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYG
EAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYR
GNATAGDLLAAFELLQIGPAGKADLPPINGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFW
GLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHP
PLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSS
SHSTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEE
PDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKE
EKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELESEFDNFEDWLHTFNLLRGKTGDDE
DGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVR
ATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVA
VYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLC
KDGKVDGPHFGPPGRVKVANRVFTGPSEIEDENGQRKPTDEHVALLALRHWEDIPRAGCR
LVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWN
TDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYL
AAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKT
AKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAE
KNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLA
LFLYSVPGYLVKKILGA

Region:1-1997
Length:1997aa
Label:Full sequence
Reset:click