Input sequence

Protein name Otoferlin
Organism Mus musculus Length 1997
Disorder content 15.1% ProS content 8.5%
IDEAL NA UniProt Q9ESF1

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 1997 1-136 137-247 248-384 385-389 390-395 396-577 578-581 582-589 590-644 645-690 691-1234 1235-1241 1242-1324 1325-1363 1364-1400 1401-1437 1438-1443 1444-1950 1951-1955 1956-1997 1-136 248-384 396-577 590-644 691-1234 1325-1363 1401-1437 1444-1950 1956-1997 137-247 390-395 582-589 645-690 1242-1324 1364-1400 1438-1443 1951-1955 149-156 166-203 240-247 645-645 681-690 1242-1255 1263-1274 1282-1299 1307-1324 1364-1400 1951-1955 1-124 1494-1574 960-1061 1-124 1493-1581 419-519 253-367 960-1093 1116-1172 841-917 338-405 1494-1577 961-1049 452-503 255-337 338-409 418-513 841-918 961-1051 1494-1577 1494-1605 248-355 955-1096 433-526 1793-1845 3-120 238-384 395-540 939-1095 1099-1223 1473-1612 1699-1866 607-618 1191-1202 1265-1276 1293-1323 1370-1385 1436-1447 1908-1920 1965-1983 794-821 1336-1363 1964-1986 3l9bA(3-126) 2e-59 93.55% 3pfqA(72-157) 3e-06 36.05% 3jzyA(3-94) 4e-05 27.45% 3l9bA(3-126) 5e-37 93.55% 2ep6A(14-99) 9e-16 30.34% 4iqhA(6-95) 2e-09 21.15% 4iqhA(3-119) 1e-06 15.97% 3jzyA(3-121) 3e-12 23.88% 3fc3A(15-69) 0.0002 33.33% PF08150(1-75) 1e-23 63.64% PF08151(1-68) 3e-17 57.35% PF00168(1-85) 7e-09 34.12% PF00168(1-83) 3e-08 32.98% PF00168(21-74) 0.0005 40.0% PF00168 5.3e-12 50.5% PF08151 3.9e-53 187.1% PF00168 6.9e-18 70.0% PF08150 2.7e-59 207.6% PF00168 3.8e-16 64.3% PF00168 1.7e-21 82.0% 1a25A(17-132) 4e-14 23.28% 1n05A(10-138) 8e-12 7.75% 2nq3A1(2-130) 4e-11 16.2% 2cjsA1(1-91) 2e-09 22.34% 2ex0A1(332-385) 0.0003 18.52% b.7.1 8.7e-10 33.1% b.7.1 2.1e-18 58.3% b.7.1 3.6e-23 73.5% b.7.1 6.8e-20 63.0% b.7.1 1.2e-11 39.9% b.7.1 2.6e-29 93.1% b.7.1 1.7e-19 67.6%

Sequence

MALIVHLKTVSELRGKGDRIAKVTFRGQSFYSRVLENCEGVADFDETFRWPVASSIDRNE
VLEIQIFNYSKVFSNKLIGTFCMVLQKVVEENRVEVTDTLMDDSNAIIKTSLSMEVRYQA
TDGTVGPWDDGDFLGDESLQEEKDSQETDGLLPGSRPSTRISGEKSFRRAGRSVFSAMKL
GKTRSHKEEPQRQDEPAVLEMEDLDHLAIQLGDGLDPDSVSLASVTALTSNVSNKRSKPD
IKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYF
VFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSD
PDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYV
KIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQ
VVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYG
STRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPELTSSTEVQVEQATPVSE
SCTGRMEEFFLFGAFLEASMIDRKNGDKPITFEVTIGNYGNEVDGMSRPLRPRPRKEPGD
EEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQITDRNYFHLPYLERKPCIYIKSWWPDQ
RRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLEELSCGCHRFLSLSDKD
QGRSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRLCQNFLQKLRFLADE
PQHSIPDVFIWMMSNNKRIAYARVPSKDLLFSIVEEELGKDCAKVKTLFLKLPGKRGFGS
AGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQAFQ
LRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGE
AHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRG
SATAGDLLAAFELLQIGPSGKADLPPINGPVDMDRGPIMPVPVGIRPVLSKYRVEVLFWG
LRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPP
LNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPNWNTTVRLLRGCHRLRNGGPSS
RPTGEVVVSMEPEEPVKKLETMVKLDATSDAVVKVDVAEDEKERKKKKKKGPSEEPEEEE
PDESMLDWWSKYFASIDTMKEQLRQHETSGTDLEEKEEMESAEGLKGPMKSKEKSRAAKE
EKKKKNQSPGPGQGSEAPEKKKAKIDELKVYPKELESEFDSFEDWLHTFNLLRGKTGDDE
DGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDPTYGMFQGIPSNDPINVLVRIYVVR
ATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVA
VYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLC
KEGKVDGPHFGPHGRVRVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCR
LVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWN
TDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYL
AAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKT
AKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAE
KNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKFLLLFLLLLLFA
LFLYSLPGYLAKKILGA

Region:1-1997
Length:1997aa
Label:Full sequence
Reset:click