Input sequence

Protein name Otoferlin
Organism Rattus norvegicus Length 1993
Disorder content 18.2% ProS content 11.3%
IDEAL NA UniProt Q9ERC5

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 1993 1-122 123-126 127-262 263-400 401-405 406-414 415-593 594-597 598-604 605-662 663-707 708-1254 1255-1335 1336-1339 1340-1400 1401-1404 1405-1411 1412-1431 1432-1440 1441-1944 1945-1951 1952-1993 1-122 263-400 415-593 605-662 708-1254 1336-1339 1401-1404 1412-1431 1441-1944 1952-1993 127-262 406-414 598-604 663-707 1255-1335 1340-1400 1405-1411 1432-1440 1945-1951 127-156 180-208 218-223 257-260 262-262 411-414 676-682 697-707 1255-1269 1278-1296 1320-1335 1340-1400 1405-1411 1432-1440 1945-1951 1-124 1490-1570 976-1077 1-124 1489-1577 435-535 269-383 976-1109 1132-1188 857-933 354-421 1490-1573 977-1065 468-519 271-353 354-425 434-529 857-934 977-1067 1490-1573 1490-1601 968-1115 264-371 449-542 1789-1841 3-115 254-400 411-556 955-1111 1115-1239 1469-1608 1695-1862 623-634 1207-1218 1261-1272 1285-1320 1366-1382 1432-1443 1904-1916 1961-1982 810-837 1960-1982 3l9bA(3-126) 8e-64 100.0% 3pfqA(72-157) 3e-06 36.05% 3jzyA(3-94) 5e-05 27.45% 3l9bA(3-126) 9e-39 100.0% 2ep6A(14-99) 9e-16 30.34% 4iqhA(6-95) 2e-09 21.15% 4iqhA(3-119) 1e-06 15.97% 3jzyA(3-121) 4e-12 23.88% 3fc3A(15-69) 0.0002 33.33% PF08150(1-75) 1e-23 63.64% PF08151(1-68) 3e-17 57.35% PF00168(1-85) 7e-09 34.12% PF00168(1-83) 4e-08 32.98% PF00168(21-74) 0.0005 40.0% PF00168 5.3e-12 50.5% PF08151 3.9e-53 187.1% PF00168 6.9e-18 70.0% PF08150 2.7e-59 207.6% PF00168 3.4e-16 64.4% PF00168 1.7e-21 82.0% 1a25A(17-132) 4e-14 23.28% 1wfjA(3-134) 6e-11 16.11% 1n05A(10-138) 8e-12 7.75% 2cjsA1(1-91) 2e-09 22.34% 2ex0A1(332-385) 0.0003 18.52% b.7.1 5.8e-10 31.4% b.7.1 2.1e-18 58.3% b.7.1 3.6e-23 73.5% b.7.1 2.8e-20 64.3% b.7.1 1.2e-11 39.9% b.7.1 2.6e-29 93.1% b.7.1 1.7e-19 67.6%

Sequence

MALIVHLKTVSELRGRADRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNE
VLEIQIFNYSKVFSNKLIGTFRMVLQKVVEENRVEVSDTLIDDNNAIIKTSLSMEVRYQA
ADGTVGPWDDGDFLGDESLQEEEKDSQETDGLLPGSRPSTRTPGEKSFRSKGKEKTKGGR
DGEHKAGRSVFSAMKLGKTRSHKEEPQRQDEPAVLEMEDLDHLAIRLGDGLDPDSVSLAS
VTALTSNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKY
TSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVY
SQPEHQFHHKWAILSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLL
LPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKG
KTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGD
KGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPEL
TSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDRKNGDKPVTFEVTIGNYGNEVD
GTSRPQRPRPRKEPGDEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQITDRNYFHLPY
LERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLE
ELSCGCHRFLSLSDKDQGHSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKL
RLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFSIVEEELGKDCAK
VKTLFLKLPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLH
SFPPISLVYTKKQTFQLRAHMYQARSLFAADSTGLSDPFARVFFINQSQCTEVLNETLCP
TWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYC
PPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPSGKADLPPINGPVDMDRGPIMPVPVG
IRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLV
KWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAANWNTTG
EVVVSMEPEVPVKKLETLVKLDATSDAVVKVDVAEDEKERKKKKKKGPSEEAEEEEPDES
MLDWWSKYFASIDTMKEQLRQHETSGIDLEEKEEMDSTEGLKGPVKNKEKSRAAKEEKKK
KNQNPGPGQGSEAPEKKKAKIDELKVYPKELESEFDNFEDWLHTFNLLRGKTGDDEDGST
EEERIVGRFKGSLCVYKVPLPEDVSREAGYDPTYGMFQGIPSNDPINVLVRIYVVRATDL
HPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDW
DLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGK
VDGPHFGPHGRVKVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPE
HVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEV
VLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEE
KIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC
TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPV
GLARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLMLALFLY
SLPGYMVKKLLGA

Region:1-1993
Length:1993aa
Label:Full sequence
Reset:click