Input sequence

Protein name Histone-lysine N-methyltransferase SETD2
Organism Homo sapiens Length 2564
Disorder content 80.4% ProS content 38.8%
IDEAL NA UniProt Q9BYW2

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 2564 1-56 57-67 68-74 75-78 79-1247 1248-1251 1252-1261 1262-1266 1267-1466 1467-1468 1469-1695 1696-1702 1703-1728 1729-1831 1832-2114 2115-2142 2143-2174 2175-2180 2181-2401 2402-2421 2422-2470 2471-2555 2556-2564 57-67 75-78 1248-1251 1262-1266 1469-1695 1729-1831 2115-2142 2175-2180 2402-2421 2471-2555 1-56 68-74 79-1247 1252-1261 1267-1466 1703-1728 1832-2114 2143-2174 2181-2401 2422-2470 2556-2564 12-23 28-56 68-74 79-96 137-152 263-269 284-288 316-329 374-397 426-434 450-460 492-496 514-534 568-573 600-628 642-651 660-676 681-693 718-744 758-798 811-841 867-879 889-899 906-911 918-960 969-984 991-1028 1032-1040 1055-1081 1095-1119 1158-1192 1203-1219 1224-1247 1252-1261 1267-1286 1292-1310 1317-1350 1369-1377 1394-1398 1450-1466 1703-1728 1850-1859 1871-1884 1905-1911 1931-1946 1952-1960 1966-1984 1998-2064 2088-2098 2110-2114 2150-2174 2181-2206 2269-2274 2394-2401 2422-2427 2556-2564 1444-1691 2462-2561 2394-2430 1444-1691 2462-2561 2144-2217 2394-2430 2468-2558 1562-1666 1544-1673 2391-2420 1468-1680 1600-1815 2394-2425 1284-1340 1470-1681 2381-2421 3-10 18-33 180-207 221-235 299-314 391-414 468-489 1036-1060 1084-1098 1911-1935 1982-1993 2074-2086 2126-2142 2218-2238 2254-2268 2271-2292 2339-2359 2375-2393 2115-2142 4fmuA(1-235) 1e-140 94.76% 2a7oA(1-100) 2e-54 100.0% 2mdiA(20-56) 1e-17 100.0% 4fmuA(1-235) 3e-71 94.76% 2a7oA(1-100) 2e-35 100.0% 1n7uA(220-292) 6e-10 24.32% 2mdcA(12-48) 2e-09 100.0% PF08236(4-90) 1e-09 44.57% PF00856(2-145) 5e-06 26.71% PF00856 3.6e-53 187.2% PF00397 9.9e-13 52.9% 1ml9A(14-260) 5e-38 20.48% 1uf2C1(4-208) 5e-25 5.09% 1i5hW(15-46) 5e-05 18.75% a.25.1 5.2e-07 20.4% b.85.7 2.1e-74 204.6% b.72.1 1.3e-08 31.6%

Sequence

MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTK
TKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEI
GDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAES
TTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKE
PPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISL
SCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKS
EDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYS
RSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSY
RDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFR
RGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSEL
RMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKN
DQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNG
FQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVD
TRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRN
LTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKC
GENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQ
EAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALK
CDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPM
EETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKN
PEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQE
ELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGW
DFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVY
DRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDT
LAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPP
GSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCE
CTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKK
GWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQK
GNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFC
GSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSR
LMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEI
IKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDP
STKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEE
EELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINEETPS
QDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTTTER
GRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRPDDRYD
TPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLGYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEPLSAP
PPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSVWDSNQQSV
SVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAH
PQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARD
PEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPKTAEA
DTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKE
LKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE

Region:1-2564
Length:2564aa
Label:Full sequence
Reset:click