Input sequence

Protein name Histone-lysine N-methyltransferase ASH1L
Organism Mus musculus Length 2958
Disorder content 75.7% ProS content 29.3%
IDEAL NA UniProt Q99MY8

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 2958 1-85 86-90 91-104 105-108 109-1276 1277-1341 1342-1358 1359-1365 1366-1377 1378-1384 1385-2023 2024-2277 2278-2473 2474-2550 2551-2569 2570-2826 2827-2904 2905-2946 2947-2958 86-90 105-108 1277-1341 1359-1365 1378-1384 2024-2277 2474-2550 2570-2826 2905-2946 1-85 91-104 109-1276 1342-1358 1366-1377 1385-2023 2278-2473 2551-2569 2827-2904 2947-2958 1-17 70-85 91-93 100-104 109-117 199-207 265-304 326-371 381-389 396-425 433-448 465-501 522-532 549-553 587-593 609-642 705-725 839-847 861-877 902-907 969-1002 1026-1050 1117-1135 1154-1159 1170-1182 1194-1207 1224-1229 1244-1276 1342-1354 1366-1377 1394-1401 1447-1453 1472-1476 1486-1493 1513-1518 1525-1556 1599-1603 1610-1614 1637-1646 1695-1706 1807-1811 1822-1826 1836-1856 1874-1882 1891-1938 1981-1998 2005-2015 2310-2319 2324-2337 2343-2373 2389-2394 2403-2415 2433-2473 2902-2904 2947-2958 2064-2275 2425-2548 2573-2625 2693-2793 2064-2275 2425-2548 2655-2811 2573-2631 2147-2250 2471-2524 2690-2783 2129-2258 2438-2527 2576-2620 2650-2787 2062-2265 2180-2374 2433-2546 2035-2266 2424-2557 2568-2625 36-46 226-237 354-368 552-571 706-717 745-753 777-791 859-873 938-948 1086-1105 1107-1121 1159-1173 1262-1273 1288-1301 1377-1388 1395-1424 1478-1491 1678-1692 1971-1983 2296-2316 2456-2470 2549-2563 2645-2653 3opeA(2-213) 1e-129 99.53% 3mqmA(1-124) 1e-50 92.74% 4l58A(1-55) 1e-13 58.18% 1w4sA(24-124) 2e-13 32.67% 3opeA(2-213) 2e-65 99.53% 3mqmA(1-124) 1e-33 92.74% 1w4sA(5-140) 5e-25 26.11% 4l58A(1-61) 4e-14 52.46% PF00856(2-145) 2e-10 31.51% PF00439(28-81) 1e-05 44.44% PF01426(22-115) 5e-05 35.05% PF00856 2e-56 198.0% PF00439 1.5e-17 68.9% PF00628 2.2e-09 41.8% PF01426 1.7e-25 95.3% 1ml9A(17-260) 2e-41 24.1% 1uf2C1(2-184) 2e-20 4.62% 1e6iA(3-110) 7e-12 24.56% b.85.7 1.2e-72 199.7% a.29.2 6.8e-23 77.3% g.50.1 5.3e-11 36.5%

Sequence

MDPRNTAMLGLGSDSEGFSRKSPSTINPGTLASKREAEIEGATEEEDPRKRNRERGTEAG
KEDGSTDAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTIKHSRK
ALKSGKMTDEKNEHCPSKWDSSKLFKKAGDATAIDCQAEESIHLHSQGESNPLSKKLSPV
HSQMADYISAAPSLVGSRDPDIKDRALLNGGTSVTEKLAQLIATCPPSKSSKAKPKKLGT
GTTVGLVSKDLIRKPGVGSIAGIIHKDLIKKPALSTAVGLVTKDPGKKPMFNAAVGLINK
DSVKKLGTGTTAVFINKDLGKKPGAITTVGLLSKESGKKLGIGIVPGLVNKESGKKLGLG
TVVGLVNKELGKKLSSTVGLVAKDVTKKIVASSAMGLVNKDIGKKLLNCPMAGQLGSKDA
LNLKSEALLPTQEQLKASCSANISNHDSQELPESLKDSATGKAFEKSVMRHSKESMLEKF
SVRKEITNLEKEMFNEGTCIQQDNFSSSERGAFETSKHEKQPPVYCTSPDFQIGGASDAS
TAKSPFSAVGESNLPSSSPTVSVNPVTRSPPEASSQLVPNPLLLNSTAEQMEEISESIGK
SQFTAESTHLNVGHRSLGHSLSIECKGIDKELNESKNTHLDIPRISSSLGKKPSLTSDSG
IHAITPSVVNFTSLFSNKPFLKLGAVTAPDKHCQVAESLSSSFQSKPLKKRKGRKPRWTK
VVARSTCRSPKGLDLERSELFKNVSCSSLSNSSEPAKFMKTIGASSFVDHDFLKRRLPKL
SKSSAPSLALLTDSEKPSHKSFITHKLSSSMCVTSDLLSDIYKPKRGRPKSKEMPQLEGP
PKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQSLSVSPFPKKRGRPKRQMRSPVK
MKPPVLSVAPFVATESPSKLESESENHRSSSDFFESEDQLQDTDDLDDSHRQSVCSMSDL
EMEPDKKISKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTV
SSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGLLSGSPASLAVLEQTAQQAAG
SALGQILPPLLPSPASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHVHSRQ
GSMIQTLAMKKASKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPVSESHSDETIPSDSG
IGTDNNSTSDRAEKFCGQKKRRHSFEHISLIPPETSTVLNSLKEKHKHKCKRRSHDYLSY
DKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRI
NFNSFYTHPSFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSY
GMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHAGHLLLNPTKYHKK
KHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSEQPQVSMD
SGSSRSVLESLKRYRFGKDTVGDRYKHKEKHRCHMSCPHLSPSKNLINREEQWVSREPSE
SSSLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHMNLFTSAIGSCRVSNPNSSC
RKKLTDSPGLFPVQDTALNRPHRKEPLPSSERAIQSLAGSQSASDKPSQRSSESTNCSPT
RKRSSSESTSSTVNGVPSRSPRLVASMDDSVDSLLQRIVHHDEQESMEKNGDASITTVSA
PPSSSPGHSYSKERALGKSDSLLVPAVPNDSCSNIPLLSEKSASRCSPHHIKRSVVEAMQ
RQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSM
QAFQAAQFVSPELNEGEDMSLHLSPDTVTDVIEAVVQSVNLTSEHKKGVKRKNWLLEEQT
RKKQKTVPEEEEQENNKSFIETPVEIPSPLETPAEPSEPENTLQPVLALIPREKKAPRPP
KKKYQRAGLYSDVYKTIDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLRQKRIDF
QLPYDILWQWKHNQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCG
DDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQF
IIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCE
MQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQR
MNGLPSHKGSQSSSTHRKSARAKEKRKSKHKLKKRKGHPSEEPSENINTPTRLTPQLQMK
PMSNRERNFVLKHHVFLVRNWEKIHQKQEEVKHTRDIHSASLYTRWNGLCRDDGNIKSDV
FMTQFSALQTARSVRTRRLAAAEENLEVARAARLAQIFKEICDGIISYRDSSQQTLAAPL
LNLPPKKKNADYYEKISDPLDLSTIEKQILIGYYKTVEAFDADMLKVFRNAEKYYGRKSP
IGRDVCRLRKAYYSARHEASAQIDEIVGETASEADSSETSVSEKESGHEKDDDVIRCICG
LYKDEGLMIQCDKCMVWQHCDCMGVNTDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCV
YFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIEKLWKNE
KEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGR
PKGIKEQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKRDFSPHYVPD
NYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLASQEQAAREVPSPEEPDQERATG
DIGDAEKKPEESSQEAQLASTPEERRHSQRERLNQILLNLLEKIPGKNAIDVTYLLEEGS
GRKLRRRTLFIPENSFRK

Region:1-2958
Length:2958aa
Label:Full sequence
Reset:click