Input sequence

Protein name Smoothened homolog
Organism Homo sapiens Length 787
Disorder content 36.5% ProS content 23.1%
IDEAL NA UniProt Q99835

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 787 1-64 65-557 558-773 774-780 781-787 65-557 774-780 1-64 558-773 781-787 6-24 31-64 558-590 596-608 615-646 679-683 690-693 700-707 730-741 759-773 781-787 190-550 64-178 184-550 64-178 222-552 70-176 64-179 220-555 68-176 68-192 2-31 38-53 639-648 667-680 684-698 232-254 264-286 317-339 359-381 402-424 450-472 520-537 4jkvA(109-454) 5e-90 51.8% 4c79A(2-117) 4e-46 70.69% 4jkvA(103-454) 1e-96 51.23% 4c79A(2-117) 2e-33 70.69% PF01534(3-317) 2e-55 35.14% PF01392(1-106) 3e-07 36.04% PF01392 3e-31 114.4% PF01534 5.4e-188 635.1% 1ijxA(1-109) 2e-17 27.19% a.141.1 3e-29 97.4%

Sequence

MAAARPARGPELPLLGLLLLLLLGDPGRGAASSGNATGPGPRSAGGSARRSAAVTGPPPP
LSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWA
VIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTN
EVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAV
TGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGT
MRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYF
HLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLI
RGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEW
ERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKA
TLLIWRRTWCRLTGQSDDEPKRIKKSKMIAKAFSKRHELLQNPGQELSFSMHTVSHDGPV
AGLAFDLNEPSADVSSAWAQHVTKMVARRGAILPQDISVTPVATPVPPEEQANLWLVEAE
ISPELQKRLGRKKKRRKRKKEVCPLAPPPELHPPAPAPSTIPRLPQLPRQKCLVAAGAWG
AGDSCRQGAWTLVSNPFCPEPSPPQDPFLPSAPAPVAWAHGRRQGLGPIHSRTNLMDTEL
MDADSDF

Region:1-787
Length:787aa
Label:Full sequence
Reset:click