Input sequence

Protein name Mitogen-activated protein kinase kinase kinase 5
Organism Homo sapiens Length 1374
Disorder content 21.3% ProS content 5.7%
IDEAL NA UniProt Q99683

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 1374 1-88 89-100 101-109 110-527 528-535 536-657 658-673 674-940 941-1040 1041-1172 1173-1237 1238-1287 1288-1307 1308-1371 1372-1374 89-100 110-527 536-657 674-940 1041-1172 1238-1287 1308-1371 1-88 658-673 941-1040 1173-1237 1288-1307 1372-1374 6-24 52-58 658-673 960-968 982-995 1013-1017 1037-1040 1173-1176 670-937 670-937 686-933 675-938 614-937 685-939 1307-1373 33-43 69-93 454-472 938-954 1218-1231 1254-1266 1238-1287 2clqA(1-260) 1e-147 97.01% 2clqA(1-260) 4e-121 97.01% PF00069(7-253) 8e-36 38.74% PF00069 1.2e-77 268.5% 1nw1A(37-354) 2e-42 7.25% d.144.1 1.8e-76 245.3% a.60.1 2.8e-11 42.1%

Sequence

MSTEADEGITFSVPPFAPSGFCTIPEGGICRRGGAAAVGEGEEHQLPPPPPGSFWNVESA
AAPGIGCPAATSSSSATRGRGSSVGGGSRRTTVAYVINEASQGQLVVAESEALQSLREAC
ETVGATLETLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANN
IILYCDTNSDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQP
NFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIR
QRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALN
RRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFK
KAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGF
FLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVD
FWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIH
EWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRS
TEEGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQ
PLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTI
GFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFT
GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVH
PEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNE
YLRSISLPVPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGERDVKGIRTLFLGI
PDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKIVRNLMESLAQGAEEP
KLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNK
VLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDVEDDHEE
QPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELV
RKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSSGTNTEDSELTDWLRVN
GADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQT

Region:1-1374
Length:1374aa
Label:Full sequence
Reset:click