Input sequence

Protein name E3 ubiquitin-protein ligase Itchy homolog
Organism Homo sapiens Length 903
Disorder content 35.8% ProS content 10.6%
IDEAL IID00178 UniProt Q96J02

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 903 1-16 17-123 124-127 128-138 139-438 439-513 514-516 517-903 17-123 128-138 439-513 517-903 1-16 124-127 139-438 514-516 1-4 124-127 139-144 240-246 334-346 351-405 435-438 514-516 525-897 13-145 438-517 359-471 359-392 328-357 525-897 13-145 438-517 359-392 326-363 599-901 20-96 441-469 20-99 328-357 360-389 440-469 480-509 598-903 527-898 483-564 342-399 13-145 435-473 319-363 3-147 317-357 359-391 429-471 475-511 525-898 236-247 250-267 282-298 3tugA(1-334) 0.0 89.01% 2nq3A(1-131) 3e-69 98.5% 4rohA(1-76) 9e-41 95.0% 4rohA(2-70) 5e-12 35.4% 2kykA(6-39) 2e-15 100.0% 2dmvA(8-37) 4e-13 100.0% 3tugA(1-334) 5e-65 86.86% 2nq3A(1-131) 4e-45 98.5% 4rohA(1-76) 1e-25 95.0% 2kykA(6-39) 5e-15 100.0% 2dmvA(6-43) 4e-14 81.58% PF00632(1-295) 7e-81 50.49% PF00168(1-82) 8e-07 35.37% PF00397(2-30) 0.0004 62.07% PF00168 1.4e-16 65.6% PF00397 2.3e-14 58.3% PF00397 2.9e-14 58.0% PF00397 2.4e-17 68.2% PF00397 2.1e-13 55.1% PF00632 2e-187 633.2% 1nd7A(3-374) 1e-124 79.84% 1pu1A(2-91) 7e-18 6.67% 2pstX1(6-61) 6e-16 17.24% 2nq3A1(1-131) 8e-16 94.74% 1i5hW(7-45) 3e-12 66.67% 1i5hW(3-50) 3e-09 37.5% b.7.1 8.5e-19 59.6% b.72.1 3.5e-12 43.0% b.72.1 1.5e-11 40.9% b.72.1 7.2e-14 48.6% b.72.1 2.3e-11 40.2% d.148.1 7.6e-137 463.7%

Sequence

MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLGGDKEPTETIGDLSICLDGLQLESEVVTNGETTCSENGVSLCLPRLECNSAISAHCNL
CLPGLSDSPISASRVAGFTGASQNDDGSRSKDETRVSTNGSDDPEDAGAGENRRVSGNNS
PSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNTSEG
ATSGLIIPLTISGGSGPRPLNPVTQAPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPL
PPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIY
GNQDLFATSQSKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPL
PEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQ
QLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLL
SHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFS
LPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEILGEIKSHDL
KPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEV
LLCGMQEIDLNDWQRHAIYRHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVG
GFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGF
GQE

Region:1-903
Length:903aa
Label:Full sequence
Reset:click