Input sequence

Protein name DNA topoisomerase I, mitochondrial
Organism Homo sapiens Length 601
Disorder content 8.0% ProS content 3.7%
IDEAL NA UniProt Q969P6

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 601 1-43 44-514 515-519 520-601 44-514 520-601 1-43 515-519 1-11 38-43 515-519 51-464 556-601 51-491 548-601 51-265 269-488 51-265 269-509 51-266 267-491 547-601 37-266 267-601 2-16 158-173 495-507 516-538 146-173 480-514 520-554 1a31A(1-414) 7e-180 72.46% 1a31A(413-457) 5e-14 71.74% 1a31A(1-443) 4e-152 68.62% 2b9sB(1-52) 8e-15 51.85% PF02919(1-215) 2e-75 61.4% PF01028(3-217) 4e-69 60.0% PF02919 2.4e-140 476.8% PF01028 1.2e-129 441.3% 1a31A2(1-216) 5e-104 68.06% 1a31A1(1-228) 4e-93 68.86% 1a31A1(193-242) 2e-16 61.82% e.15.1 1.6e-105 358.9% d.163.1 3.8e-90 303.1%

Sequence

MRVVRLLRLRAALTLLGEVPRRPASRGVPGSRRTQKGSGARWEKEKHEDGVKWRQLEHKG
PYFAPPYEPLPDGVRFFYEGRPVRLSVAAEEVATFYGRMLDHEYTTKEVFRKNFFNDWRK
EMAVEEREVIKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQQEFGYCILD
GHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEPPAGHQWKEV
RSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRAD
WKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHV
VEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGL
TAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSM
QNLQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQ
ATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFE
F

Region:1-601
Length:601aa
Label:Full sequence
Reset:click