Input sequence

Protein name Rho guanine nucleotide exchange factor 12
Organism Mus musculus Length 1543
Disorder content 52.2% ProS content 18.9%
IDEAL NA UniProt Q8R4H2

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 1543 1-64 65-147 148-198 199-259 260-367 368-532 533-536 537-568 569-766 767-1067 1068-1079 1080-1133 1134-1495 1496-1532 1533-1543 65-147 199-259 368-532 537-568 767-1067 1080-1133 1496-1532 1-64 148-198 260-367 569-766 1068-1079 1134-1495 1533-1543 6-36 43-46 188-198 275-295 303-323 348-367 569-635 708-712 757-766 1072-1079 1134-1139 1229-1234 1246-1270 1277-1283 1290-1294 1324-1328 1371-1385 1407-1420 1477-1482 1539-1543 766-1138 67-151 370-558 766-1138 370-558 66-151 372-558 792-975 81-144 72-145 791-976 370-558 766-999 996-1133 71-155 55-165 370-559 766-998 1020-1133 49-64 213-225 293-313 583-596 663-676 721-733 1256-1269 199-259 1txdA(1-352) 0.0 91.42% 2omjA(5-89) 6e-42 98.82% 1iapA(1-189) 2e-36 41.58% 1txdA(1-352) 1e-91 91.15% 1iapA(1-189) 5e-50 41.58% 2omjA(4-89) 2e-32 97.67% PF09128(5-188) 4e-43 51.87% PF00621(2-178) 2e-29 37.84% PF00595(11-81) 0.0005 39.44% PF00595 2.1e-12 51.8% PF00621 8.5e-20 76.4% 1iapA(1-189) 2e-67 41.58% 1txdA1(1-234) 3e-54 96.15% 1xcgA2(1-126) 1e-29 48.2% 1vaeA(17-103) 1e-20 25.29% b.36.1 2.7e-25 79.2% a.91.1 2.5e-71 225.8% a.87.1 1.1e-64 225.4% b.55.1 4.4e-42 132.9%

Sequence

MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSSSHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIRSGSYVALTVQGRPPGSPQIPLADSEVEPSVTGHMSPIMTSPHSPG
AAGNMERITSPVLVGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTATQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVIAPSRPLGDALTLSEAEADPGDGLCRTDWSSGDAS
RPSSDSADSPKSSLRERSYLEEAPERSEGVQDAEPQSLVGSPSTRGAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLKVPVPEEISVDLEKRRPELIPEDLHRLYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRGTLEKERACAEQIVTKIEEVLMTAQAVEEER
SSTMQYVILMYMKYLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMEIQKSRHPKHLSTPSSVSPEPQDPAKLRQSGVANEGTDTGY
LPASSMSSATSGTALSQEGGRENDTGTKQVGEASAPGDCLDSTPRVPTTVFDFPPPLLDQ
VQEEECEVERVAEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHVGLNEQMKAVRKRNETSVIDHIGEDLLIWFSGPGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFHTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPPEREKV
KKAADHCRQILNYVNQAVREAENKQRLEDYQRRLDTSNLKLSEYPNVDELRNLDLTKRKM
IHEGPLVWKVNRDKSIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK
PIPLPQPPPCEGDNDEEEPAKLKVEHHDLSVAGLQSPDRVLGLESPLISSKPQSHSLNTP
GKSAAEHLFVTATQFAKEQHANGALKEGDGGYPVTIPGPHLPVSEERWALDALRNLGLLK
QLLVQQLGLTEKSTQEDWQSFSRYGPASEEVQADSGIRDLENVKACHAREGQMSFKTGTG
DIATCDSPRTSTESCAAQDSVILASQDSQASNVLVMDHMILTPEMPPAEPEGGLDESGEH
FFDAREAHSDDNPSEGDGAVKKEEKDVNLRISGNCLILDGYDAVQESSTDEEVASSFPLQ
PVTGIPAVDSSHQQQHSPQNVHPEGPVSPFTPEFLVQRHWRAMEDTCFEIQSPSCTDSQS
QILEYIHKIEADLEHLKKVEESYALLCQRLAGSALPDKLSDKS

Region:1-1543
Length:1543aa
Label:Full sequence
Reset:click