Input sequence

Protein name E3 ubiquitin-protein ligase HECW1
Organism Homo sapiens Length 1606
Disorder content 50.1% ProS content 9.7%
IDEAL NA UniProt Q76N89

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 1606 1-15 16-78 79-185 186-200 201-349 350-830 831-862 863-870 871-898 899-1112 1113-1152 1153-1165 1166-1202 1203-1212 1213-1606 1-15 79-185 201-349 831-862 871-898 1113-1152 1166-1202 1213-1606 16-78 186-200 350-830 863-870 899-1112 1153-1165 1203-1212 16-21 29-54 60-78 350-357 460-464 487-499 533-538 796-799 958-967 973-978 1011-1053 1203-1212 1226-1600 948-1056 82-181 830-861 1226-1600 948-1056 82-181 830-865 213-341 1302-1605 207-302 831-860 1020-1049 1301-1606 1226-1600 222-345 825-866 1023-1110 213-348 820-862 1009-1051 1247-1600 65-81 374-390 500-509 572-589 675-708 905-929 1195-1210 1214-1225 871-898 2xbbA(2-374) 2e-108 49.2% 3l4hA(1-107) 4e-55 98.17% 2lfeA(5-105) 5e-34 63.37% 2kykA(6-37) 3e-09 71.88% 2xbbA(2-374) 2e-49 48.94% 3l4hA(1-107) 2e-33 96.33% 2lfeA(6-105) 1e-27 63.0% 2dmvA(7-42) 1e-11 58.33% 2jqzA(11-128) 4e-05 20.0% PF00632(1-296) 2e-62 45.13% PF00168 5e-11 47.2% PF00397 1.6e-14 58.8% PF00397 2.4e-09 41.7% PF00632 1.1e-177 600.9% 1nd7A(3-373) 1e-104 49.2% 2ep6A1(23-126) 4e-10 16.0% 1jmqA(3-44) 3e-08 38.1% 1pu1A(2-87) 1e-07 10.23% b.7.1 6.7e-11 34.4% b.72.1 5.2e-12 42.4% b.72.1 7.8e-12 41.8% d.148.1 3.7e-126 378.7%

Sequence

MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPDDEEISLSTEPE
SAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEAA
VITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAPA
STKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPVS
ELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDGL
SEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESDS
SPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRFS
SVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGHV
ERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARID
SHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEED
SGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFITN
PEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLEL
PRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEAS
EVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLA
RNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPRC
SPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLL
EGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSAN
DTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSDL
EYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYI
ERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTE
YRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIE
KWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE

Region:1-1606
Length:1606aa
Label:Full sequence
Reset:click