Input sequence

Protein name Rho guanine nucleotide exchange factor 18
Organism Homo sapiens Length 1361
Disorder content 55.2% ProS content 28.3%
IDEAL NA UniProt Q6ZSZ5

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 1361 1-421 422-793 794-800 801-846 847-850 851-887 888-980 981-1018 1019-1034 1035-1147 1148-1361 422-793 801-846 851-887 981-1018 1035-1147 1-421 794-800 888-980 1019-1034 1148-1361 6-41 57-66 77-104 111-121 147-174 207-219 231-243 248-337 380-395 405-421 794-800 888-892 906-918 926-931 939-944 950-956 968-980 1019-1022 1148-1148 1154-1174 1189-1192 1209-1216 1222-1225 1248-1252 1277-1284 1351-1361 423-787 419-788 454-642 451-643 685-786 428-665 663-787 426-666 685-787 13-24 74-94 565-581 704-715 791-802 1062-1115 1120-1143 1224-1234 1244-1252 1299-1320 1325-1350 1035-1147 4d0nB(5-369) 4e-101 53.7% 4d0nB(1-370) 2e-76 53.24% PF00621(4-178) 1e-16 30.16% PF00621 2.2e-19 75.0% PF00169 3.2e-10 44.6% 1txdA1(3-233) 6e-38 28.99% 1xcgA2(4-126) 4e-21 30.95% a.87.1 4.3e-58 202.4% b.55.1 7.8e-37 116.4%

Sequence

MGDDQEDDFPRRLSESMEDLSLDLGALQGSEYLQDLGLGAPSHSQPGETPDSRPTGEEPG
RDSLFSSLAGSQDLSRRRSWERSRSCSESWRRLSLDASAVDEEPCLPRTLASLALNLPGG
GLKTWTQGCLSGGGTPAESPGKECDSPKKRGRSRSVPVSFYEIRSPEISPGLEVPTPPVQ
GLEPPVLECMEKDHVEPDHVLIVQQVLQELRQYHGARQRACMSASPGGAHSNLTWFEFLS
ESEDGAGKNEKSDKSTSVKRRLSCLRSRVTRQKEKGKSPAHLKDKGQDARERRECVNGHQ
LLQGTFSGPSSCPLCGKPFLSSASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPS
PAGPGTQLGPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESD
GHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYELMQTEVHHVRTLKIMLKVYSRALQEE
LQFSSKAIGRLFPCADDLLETHSHFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSG
ENGERMKEKYGVFCSGHNEAVSHYKLLLQQNKKFQNLIKKIGNFSIVRRLGVQECILLVT
QRITKYPVLVERIIQNTEAGTEDYEDLTQALNLIKDIISQVDAKVSECEKGQRLREIAGK
MDLKSSSKLKNGLTFRKEDMLQRQLHLEGMLCWKTTSGRLKDILAILLTDVLLLLQEKDQ
KYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASLQGPEMYEIYTSSKEDRNAWMAH
IQRAVESCPDEEEGPFSLPEEERKVVEARATRLRDFQERLSMKDQLIAQSLLEKQQIYLE
MAEMGGLEDLPQPRGLFRGGDPSETLQGELILKSAMSEIEGIQSLICRQLGSANGQAEDG
GSSTGPPRRAETFAGYDCTNSPTKNGSFKKKVSSTDPRPRDWRGPPNSPDLKLSDSDIPG
SSEESPQVVEAPGTESDPRLPTVLESELVQRIQTLSQLLLNLQAVIAHQDSYVETQRAAI
QEREKQFRLQSTRGNLLLEQERQRNFEKQREERAALEKLQSQLRHEQQRWERERQWQHQE
LERAGARLQEREGEARQLRERLEQERAELERQRQAYQHDLERLREAQRAVERERERLELL
RRLKKQNTAPGALPPDTLAEAQPPSHPPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARR
DSAPTENRLAKSDVPIQLLSATNQFQRQAAVQQQIPTKLAASTKGGKDKGGKSRGSQRWE
SSASFDLKQQLLLNKLMGKDESTSRNRRSLSPILPGRHSPAPPPDPGFPAPSPPPADSPS
EGFSLKAGGTALLPGPPAPSPLPATPLSAKEDASKEDVIFF

Region:1-1361
Length:1361aa
Label:Full sequence
Reset:click