Input sequence

Protein name Histone-lysine N-methyltransferase 2D
Organism Mus musculus Length 5588
Disorder content 74.2% ProS content 12.0%
IDEAL NA UniProt Q6PDK2

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 5588 1-61 62-94 95-105 106-394 395-1313 1314-1516 1517-1535 1536-1541 1542-1982 1983-2006 2007-2012 2013-2017 2018-2020 2021-2629 2630-2668 2669-2765 2766-2812 2813-3560 3561-3609 3610-3710 3711-3748 3749-3852 3853-3885 3886-3909 3910-4005 4006-4021 4022-4051 4052-4829 4830-4840 4841-4844 4845-4873 4874-5060 5061-5399 5400-5426 5427-5588 62-94 106-394 1314-1516 1536-1541 1983-2006 2018-2020 2630-2668 2766-2812 3561-3609 3711-3748 3853-3885 3910-4005 4022-4051 4830-4840 4845-4873 5061-5399 5427-5588 1-61 95-105 395-1313 1517-1535 1542-1982 2013-2017 2021-2629 2669-2765 2813-3560 3610-3710 3749-3852 3886-3909 4006-4021 4052-4829 4874-5060 5400-5426 57-61 395-420 1209-1212 1221-1223 1227-1232 1238-1244 1249-1257 1291-1296 1542-1559 1576-1581 1603-1610 1628-1639 1645-1669 1688-1692 1720-1740 1783-1786 1795-1800 1824-1830 1841-1855 1907-1921 1961-1982 2013-2017 2021-2024 2032-2035 2185-2191 2227-2231 2332-2336 2405-2408 2869-2875 3004-3066 3406-3413 3496-3512 3525-3534 3544-3553 3697-3701 4513-4520 4535-4544 4594-4608 4618-4667 4685-4707 4725-4800 4805-4810 4874-4876 4892-4931 4936-4956 5010-5018 5032-5049 5400-5404 220-323 1336-1434 5438-5588 1957-2034 5231-5368 5223-5370 220-326 1336-1436 5434-5587 5082-5187 156-218 1951-2034 1463-1512 5305-5372 5232-5283 5461-5563 228-276 278-323 1335-1386 1387-1433 1462-1515 5231-5284 5287-5374 5442-5570 5450-5570 276-321 1353-1438 3498-3559 225-281 1957-2029 220-273 274-324 1327-1383 1384-1434 1455-1520 1978-2029 5428-5588 135-145 430-489 500-562 564-613 619-717 735-755 826-842 844-919 958-981 985-1023 1069-1076 1139-1153 1259-1285 1307-1314 1514-1538 1567-1576 1589-1612 1634-1646 1707-1719 1883-1896 1931-1950 2064-2079 2147-2167 2170-2181 2306-2323 2334-2359 2366-2388 2402-2419 2546-2559 2610-2622 2634-2655 2665-2680 2769-2819 2855-2868 2887-2899 3151-3165 3189-3204 3241-3263 3269-3284 3390-3400 3596-3610 3629-3659 3677-3682 3712-3767 3781-3801 3809-3816 3859-3883 3913-4010 4024-4049 4128-4159 4167-4183 4226-4246 4266-4293 4306-4322 4361-4378 4602-4615 4661-4684 4745-4755 4877-4896 4957-4983 4989-5029 5100-5107 5545-5553 2630-2668 2766-2812 3561-3609 3711-3748 3853-3885 3910-4005 4022-4051 2ysmA(1-104) 2e-41 64.42% 2ysmA(10-105) 3e-19 42.42% 2w5yA(27-170) 2e-30 45.03% 2yukA(10-87) 8e-26 64.1% 2wzoA(9-139) 5e-12 28.06% 2wzoA(1-141) 5e-26 27.52% 2ysmA(1-107) 5e-22 62.62% 2ysmA(10-107) 3e-13 41.58% 4yz8A(63-211) 4e-21 27.74% 4nn2A(4-122) 2e-20 24.17% 4nn2A(57-123) 5e-08 25.37% 2yukA(4-87) 5e-20 59.52% 2kyuA(8-63) 0.0002 31.58% PF05965(17-84) 5e-10 48.53% PF05964(2-52) 7e-10 48.08% PF00856(3-145) 1e-05 27.59% PF00628 9.3e-13 53.0% PF00628 1.7e-10 45.5% PF00628 5.4e-11 47.1% PF00628 3.3e-11 47.8% PF00628 2.2e-05 28.5% PF05964 1.3e-20 79.1% PF05965 5.7e-36 130.1% PF00856 2.1e-49 174.7% 1h3iA2(23-149) 6e-27 23.48% 1f62A(3-48) 1e-12 41.3% 1e7dA2(23-96) 4e-12 13.79% 1xeqA1(24-84) 2e-08 8.06% 1mm2A(5-61) 7e-07 26.32% 1y71A1(30-104) 9e-06 6.67% g.50.1 2.1e-09 34.2% g.50.1 4.1e-12 41.3% g.50.1 6.2e-08 28.9% g.50.1 1.8e-12 42.6% g.50.1 7.1e-09 29.6% a.21.1 5.3e-06 21.5% b.85.7 7.7e-54 173.5%

Sequence

MDSQKPPAEDKDSDPAADGLAAPEKPGATEPDLPILCIGEVSVPGSGGSRPQKPPHDCSR
GPARRCALCNCGEPGLHGQRELQRFELPSDWPGFPVVPSGGNSGPCEAVLPKEDASQIGF
PEGLTPAHLGEPGGHCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCARFGA
SVPCRSPGCSRLYHFPCATASGSFLSMKTLQLLCPEHSDGAAHLEEARCAVCEGPGQLCD
LLFCTSCGHHYHGACLDTALTARKRASWQCPECKVCQSCRKPGNDSKMLVCETCDKGYHT
FCLKPPMEDLPAHSWKCKTCRLCRACGAGSAELNPNSEWFENYSLCHRCHKAQGSQPVTS
VAEQHPAVCSRLSPPEPGEIPIDAPDALYVACQGQPKGGHVTSMQPKELAPLQCEAKPLG
RAGTQLEAQLEAPLHEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPTEESPLSPPP
ESSPFSPLEGCPPSPALDTPLSPPPEASPLSPPFEESPLSPPPEELPSSPPPEASRLSPP
PEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEDSPLSPPPEASRLSPPPEDSPM
SPPPEDSPMSPPPEVSRFLPLPVLSHLSPLPEVSRLSPPPEESPLSPPPEDSPASPPPEA
SRLSPPPEDSPASPPPEASRLSRPREDSPASPPPEDSLVSLPMEESPLSPLPEELRLCPQ
PEEPYLSPQPEEPRLCPQPEELPLSPQSEEPCLSPVLVEPGPSSQPEEPHLSPVPQEPHL
SPQPEEPHLSPQPQQLHLSPHSEEPCLSPMPEEPCLSPQPEELNGPPQPAEPPEEPSQSS
APKELSLFSPSGEPPLPPMLGEPALSEPGEPPLSPLPEELPLSLSGEPVLSPQLMPPDPL
PPPLSPIIPAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEP
VPPMILPPSPGSPLGPASPILMERLPPPCSPLLPHSLPPPTPPPSHCSPPALPLSVPSPL
SPVQKAVDVSDEAELHEMETDKGPEPECPALEPRATSPLPSPLGDLSCPAPSPAPALDDF
SGLGEDTAPLDGTGQMSGSLAGELKGSPVLLDPEELTPVTPMEVYGPECKQAGQGSPCEE
QEEPGAPMAPMPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGV
STDVSPARDEGSLRLCTDSLPETDDSLLCDTGTATSGGKAEGDKGRRRSSPARSRIKQGR
SSSFPGRRRPRGGAAHGGRGRGRARLKSTTSSVETLVADIDSSPSKEEEEEDDDTMQNTV
VLFSNTDKFVLMQDMCVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRC
VECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQCGAAS
PGFHCEWQNSYTHCGPCASLVTCPVCHAPYVEEDLLIQCRHCERWMHAGCESLFTEDEVE
QAADEGFDCVSCQPYVVKPVVPVAPPELVPVKVKEPEPQFFRFEGVWLTETGMAVLRNLT
MSPLHKRRQRRGRLGLPGEAGLEGSEPSDALGPDDKKDGDLDTDDLLKGEGGVEQMECEI
KLEGPASPDVELGKEETEESKKRKRKPYRPGIGGFMVRQRKSHTRVKRGPAAQAEVLSGD
GQPDEVMPADLPAEGSVEQSLAEGDEKKKQQRRARKKSKLEDMFPAYLQAAFFGKDLLDL
SRKALFAVGVGRPGFGLGASKPRADGGSDRKELMTAMHKGDDGPDVADEESHGPEGTADL
PGLEDGGVKASPVPSDPEKPGTPGEGVLSSDLDRIPTEELPKMESKDLQQLFKDVLGSER
EQHLGCGTPGLEGGRTSLQRPFLQGGLALGSLPSSSPMDSYPGLCQSPFLDSRERGGFFS
PEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLY
ANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRISKVQKQAESQ
ISKQAKMGDIARKTDRPALHLRIPSQPGALGSPPPAAAPTIFLGSPTTPAGLSTSADGFL
KPPAGTVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYAPEPRFSAAPPTYPPYPSPT
GAPAQPPMLGTTTRPGTGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV
AGGKASEPLLSPPPFGESRKSLEVKKEELGASSPGYGPPNLGCVDSPSAGPHLGGLELKA
PDVFKAPLTPRASQVEPQSPGLGLRAQEPPPAQALAPSPPSHPDVFRSGPYPDPYAQPPL
TPRPQPPPPESCCAPPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPR
FQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGPLAHTPLGAGGFPAALPSGPA
GELHAKVPSGQPTNFARSPGTGTFVGTPSPMRFTFPQGVGEPSLKPPVPQPGLPSPHGIN
SHFGPGPTLGKPQSTNYAVATGNFHPSGSPLGPNSGPTGEGYGLSPLRPASVLPPPAPDG
SLPYLTHGASQRVGITSPVEKREDPGATMSSSSLATPELSSAQDAGISSLSQTELEKQRQ
RQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGNWGAEPSSPAFEQLSRGQTPFTGS
QDRSSIVGLPASKLGGPTLGPGAFSSDDRLARPLPPATPSSMDMNSRQLVGGSQAFYQRT
PYPGSLPLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLWQQQQQQQQQQQQQAAAAAAAT
SMRLAMSARFPSTPGPELGRQALGSPLAGIPTRLPGPAEPVPGPAGPAQFIELRHNVQKG
LGPGVSPFPGQGPPQRPRFYPVSEELHRLAPEGLRGLAVPGLPSQKPSALPAPELNNSLH
QTPHAKGPALASGLELVSRPPSNTELSRPPLALEAGKLPCEDPELDDDFDAHKALEDDEE
LAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNE
HLRLVESANEKAEREALLRGVEPVSLGPEERPPPAPDNSEPRLTSVLPEVKPKVEEGGRH
PSPCQFTINTPKVEPAPPATSLSLGLKPGQTVMGTRDTRGGVGTGSFPSSGHTAEKGPFG
ATGGTPAHLLNPSSLSGPAASSLLEKFELESGALTLPSGHAAAGDELDKMESSLVASELP
LLIEDLLEHEKKELQKKQQLSAQTVLPAQQQQQQQQQQQQQQQQHTLLPTPGPAQALPLP
HEPGPPQQLALGIGSTRQPGLGQSMVPIQPPAHALQQRLAPSVAMVSNQGHMLSGQQAGQ
TGLVPQQSSQPVLAQKPMSAMPASMCMKPQQLAMQQQQLANSFFPDTDLDKFAAEDIIDP
IAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGSGSDLQNHVAPGSGQERN
AGDPAQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALC
AKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQ
QQQQQQQQQQHSAVLAVSPSQNPRVLTKLPGQLLPAHGLQPPQAPPGGQAGGLRLPPGGM
VLPGQSGGPFLNTTLAQQQQQQHSGVAGSLTGPPGSFFPGNLALRSLGPDSRLLQERQLQ
LQQQRMQLAQKLQQQQQQQQQQQQQQHLLGQVAIQQQQGPGVQNQALGPKPQGLLPPSNH
QGLLVQQLSPQQSQGSQGLLGPAQVTVLQQQQQQQQHSGALGPQGPHRQVLMTQSRVLSS
PQLAQQGHSLMGHRLLTAQQQQQQQQQQQQQQQQQQQQQQQQQGSMTGLSQLQQGMMSHG
GQPKMSAQALGSLQQQQQQLQQQQMLQQQQLQQQQQQLQQQQQQQQLQQQQQQQLQLQQQ
QQQQQQHLQHQQQQQQQLQQQQQLQQQQQQQLHLQQQLHQQQQLQLQQQQMGLLNQNRTL
LSPQQQQQQQQQQQQQQQQQQQQQQQQQQVTLGPGLPVKPLQHFSSSGALGPTLLLTGKE
QNNAETALPSEVTEGPSTHQGGPPAVGTAPEPMSVEPGEVKPSISGDSQLLLVQSQAQSQ
ATSVQLQPPLRLPGQPQPQVNLLHTAGGGSHGQQLGSGSSSESPAVPHLLAQPSVSLGEQ
PGPMAQNLLGSQQPLGLDRPIQNNTGSQPPKSGPAPQSGQGPPGAGVMPTVGQLRAQLQG
VLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPFQEPGTQPSPLQGLLGCQPQP
GGFSVSQTGPLQELGAGSRPQGPPRLPVPQGALSTGPVLGPAHPTPPPSSPQEPKRPSQL
PSPSAQLTPTHPGTPKPQGPALELPPGRVSPAAAQLADTFFGKGLGPWDPSDNLTEAQKP
EQSSLVPGHLDQVNGQVVHEPSQLSIKQEPREEPCALGAQTVKREANGEPAGAPGTSNHL
LLAGSRSEAGHLLLQKLLRAKNVQLGAGRGPEGLRAEINGHIDSKLSGLEQKLQGTSSNK
EDAATRKPLPAKPKRVQKTSDRLPSSRKKLRKEDGVRANEALLKQLKQELSQLPLTEPTI
TANFSLFAPFGSGCLVSGQSQLRGAFGSGALHTGPDYYSQLLTKNNLSNPPTPPSSLPPT
PPPSVQQKMVNGVTPSDELGERPKDTASAQDSEGALRDAAEVKSLDLLAALPTPPHNQTE
DVRMESDEDSDSPDSIVPASSPESILGEEAPRFPQLGSGRWEQDNRALSPVIPIIPRTGI
PVFPDTKPYGVLDLEVPGKLPATAWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSM
KIPNSYEVLFPDGPARAGLEPKKGEAEGPGGKEKGLSGKGPDTGPDWLKQFDAVLPGYTL
KSQLDILSLLKQESPAPEPSIQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPP
AEPMVELQAERPAEPPIPSPLPLASSPESARPKPRARPPEESEDSRPPRLKKWKGVRWKR
LRLLLTIQKGSGHQEDEREVAEFMEQFGTALRPSKVPRDNRRCCFCHEEGDGATDGPARL
LNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGATSSCNRMRC
PNVYHFACAIRAKCMFFKDKTMLCPVHKIKGPCEQELSSFAVFRRVYIERDEVKQIASII
QRGERLHMFRVGGLVFHAIGQLLPHQMADFHSATALYPVGYEATRIYWSLRTNNRRCCYR
CSISENNGRPEFVIKVIEQGLEDLVFTDASPQAVWNRIIEPVAAMRKEADMLRLFPEYLK
GEELFGLTVHAVLRIAESLPGVESCQNYLFRYGRHPLMELPLMINPTGCARSEPKILTHY
KRPHTLNSTSMSKAYQSTFTGETNTPYSKQFVHSKSSQYRRLRTEWKNNVYLARSRIQGL
GLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGP
ARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGA
WNCRKWMN

Region:1-5588
Length:5588aa
Label:Full sequence
Reset:click