Input sequence

Protein name Volume-regulated anion channel subunit LRRC8E
Organism Homo sapiens Length 796
Disorder content 10.3% ProS content 1.1%
IDEAL NA UniProt Q6NSJ5

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 796 1-64 65-88 89-168 169-225 226-310 311-311 312-796 1-64 89-168 226-310 312-796 65-88 169-225 311-311 169-173 223-225 311-311 597-766 419-770 1-56 611-765 528-686 370-772 178-221 505-517 578-589 26-48 117-139 312-334 4mnaA(159-356) 3e-14 30.65% 4mn8A(172-480) 1e-33 25.27% PF12534(1-56) 6e-20 71.43% 1fo1A1(1-159) 7e-18 20.13% 1a9nA(11-149) 4e-06 14.55% c.10.2 3.7e-50 159.1%

Sequence

MIPVAEFKQFTEQQPAFKVLKPWWDVLAEYLTVAMLMIGVFGCTLQVTQDKIICLPNHEL
QENLSEAPCQQLLPRGIPEQIGALQEVKGLKNNLDLQQYSFINQLCYETALHWYAKYFPY
LVVIHTLIFMVCTSFWFKFPGTSSKIEHFISILGKCFDSPWTTRALSEVSGENQKGPAAT
ERAAATIVAMAGTGPGKAGEGEKEKVLAEPEKVVTEPPVVTLLDKKEGEQAKALFEKVKK
FRMHVEEGDILYTMYIRQTVLKVCKFLAILVYNLVYVEKISFLVACRVETSEVTGYASFC
CNHTKAHLFSKLAFCYISFVCIYGLTCIYTLYWLFHRPLKEYSFRSVREETGMGDIPDVK
NDFAFMLHLIDQYDSLYSKRFAVFLSEVSESRLKQLNLNHEWTPEKLRQKLQRNAAGRLE
LALCMLPGLPDTVFELSEVESLRLEAICDITFPPGLSQLVHLQELSLLHSPARLPFSLQV
FLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQLKVL
SLRSNAGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELELVACGLERIPHA
VFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYL
SYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFF
CRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDT
LYQGLPAEVRDKMEEE

Region:1-796
Length:796aa
Label:Full sequence
Reset:click