Input sequence

Protein name Tyrosine-protein kinase JAK2
Organism Mus musculus Length 1129
Disorder content 6.5% ProS content 2.0%
IDEAL IID50091 UniProt Q62120

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 1129 1-35 36-136 137-140 141-299 300-309 310-517 518-529 530-816 817-832 833-1053 1054-1058 1059-1129 36-136 141-299 310-517 530-816 833-1053 1059-1129 1-35 300-309 518-529 817-832 21-27 817-832 839-1126 536-809 43-513 535-1119 39-513 854-1123 551-805 401-481 545-805 849-1123 789-1119 538-798 397-520 33-123 141-261 390-565 534-834 834-1119 223-242 3e62A(1-286) 9e-163 96.53% 4fvqA(1-274) 2e-151 94.16% 4po6A(6-474) 1e-54 32.93% 4oliA(1-527) 1e-141 45.13% 4po6A(3-474) 7e-121 31.44% PF07714(6-254) 1e-45 40.07% PF07714(7-254) 9e-25 31.7% PF00017 0.00052 11.3% PF07714 7.3e-80 275.9% PF07714 6.8e-128 435.5% 1nw1A(35-349) 1e-34 5.6% 1nw1A(88-346) 4e-17 7.06% 1a81A1(5-123) 1e-10 18.55% 2byeA1(5-92) 1e-06 9.89% 2aehA1(5-120) 8e-06 13.22% d.93.1 1.9e-25 85.2% d.144.1 4.6e-48 155.9% d.144.1 5.2e-70 225.8%

Sequence

MGMACLTMTEMEATSTSPVHQNGDIPGSANSVKQIEPVLQVYLYHSLGQAEGEYLKFPSG
EYVAEEICVAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHDILYRIRFYF
PHWYCSGSSRTYRYGVSRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLAVYNSVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQF
SQCKATARNLKLKYLINLETLQSAFYTEQFEVKESARGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDVQLYCDFPDIIDVSIKQANQECSNESRIVTVHKQDGKVLEIELSSLK
EALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKRNFSNLKDLLNC
YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVQISPTLQRHNNVNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHKTEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVAKQLAWA
MHFLEEKSLIHGNVCAKNILLIREENRRTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLPAPKWTEL
ANLINNCMDYEPDFRPAFRAVIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFHLIE
LLKSNGRLPRPEGCPDEIYVIMTECWNNNVSQRPSFRDLSLRVDQIIAA

Region:1-1129
Length:1129aa
Label:Full sequence
Reset:click