Input sequence

Protein name Otoferlin
Organism Danio rerio Length 1992
Disorder content 14.7% ProS content 7.2%
IDEAL NA UniProt Q5SPC5

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 1992 1-130 131-253 254-390 391-397 398-401 402-585 586-605 606-652 653-699 700-1246 1247-1282 1283-1310 1311-1313 1314-1322 1323-1329 1330-1359 1360-1396 1397-1431 1432-1438 1439-1648 1649-1652 1653-1944 1945-1950 1951-1961 1962-1963 1964-1992 1-130 254-390 402-585 606-652 700-1246 1283-1310 1314-1322 1330-1359 1397-1431 1439-1648 1653-1944 1951-1961 1964-1992 131-253 398-401 586-605 653-699 1247-1282 1311-1313 1323-1329 1360-1396 1432-1438 1945-1950 1962-1963 131-153 169-173 182-192 246-253 398-401 593-605 691-694 1255-1259 1264-1282 1323-1329 1360-1396 1945-1950 1962-1963 1-124 1483-1576 969-1059 1-124 1488-1576 1809-1883 425-525 257-374 967-1102 850-926 344-411 1489-1572 970-1058 458-509 261-314 261-343 344-415 424-519 850-927 970-1060 1489-1572 1489-1600 1740-1859 254-361 963-1105 439-532 3-117 244-390 401-546 948-1104 1120-1254 1468-1607 1694-1861 200-211 659-683 1200-1211 1288-1310 1333-1354 1366-1392 1432-1442 1903-1915 1960-1978 1283-1310 1332-1359 1964-1986 3l9bA(3-126) 2e-48 71.77% 4v29A(2-91) 1e-06 34.38% 3jzyA(3-84) 0.0002 26.37% 3l9bA(3-126) 7e-36 71.77% 2ep6A(14-99) 7e-16 29.21% 2ep6A(63-122) 0.0004 24.0% 4iqhA(6-95) 9e-11 23.08% 4iqhA(1-119) 2e-07 18.85% 3jzyA(1-121) 1e-11 22.79% PF08150(1-75) 2e-24 64.94% PF08151(1-68) 1e-16 54.41% PF00168(1-85) 4e-09 34.12% PF00168(1-83) 2e-07 31.91% PF00168(21-74) 0.0004 41.82% PF00168(1-61) 0.0008 44.26% PF00168 1.4e-12 52.4% PF08151 6.2e-57 199.7% PF00168 1.8e-17 68.6% PF08150 9.1e-61 212.5% PF00168 6.7e-13 53.5% PF00168 4.9e-23 87.1% 1a25A(17-132) 3e-15 24.14% 1bdyA(11-105) 3e-05 6.67% 1n05A(10-138) 2e-11 7.75% 2nq3A1(1-130) 4e-10 14.58% 2cjsA1(1-91) 2e-09 21.28% b.7.1 1e-09 30.6% b.7.1 1.3e-19 62.2% b.7.1 3e-23 73.7% b.7.1 3e-19 61.0% b.7.1 2.6e-10 32.5% b.7.1 6.6e-30 94.9% b.7.1 6.8e-22 76.1%

Sequence

MALVVHLKTVTELRGKGDRIAKVTFRGLSFFSRVLENCEDEARFEQAFRWPIGSQVDGDE
MLEIQVFNYSKVFTNRLIGTFRMVLQKVVEEGHLEVSDTLIDDNNTAIQTTISIEIKYQT
MDGSVKVWSDGEFLDIPDDLDGTFQFETDSLLSGRSQSSGTSPGRSIHGIPTFRKAGKGV
FSAMKLGKTRTSKDDHKKGDDAAILDAEDLDRKAMRLGGILDPDTISLASVTAVTTNVSN
KRSKPDIKMEPSSGRPVDYQISVTVIEARQLVGLNMDPVVCVEIGEEKKYTSMKESTNCP
YYNEYFVFDFHVPPDVMFDKIIKISVIHSKNLLRSGTLVGTFKLDVGTVYTQPEHQFHHK
WAMLSDPDDITTGCKGYVKCDIAVVGKGDNIKTPHKASEADEDDIEGNLLLPEGVPSERQ
WARFYVKIYRAEGLPKMNTSIMANVKKAFIGENRDLVDPYVLVQFAGQKGKTSVQKSSYE
PIWNEQVIFTEMFPPLCRRLKVQIRDSDKVNDVAIGTHFIDLRKVSNDGDKGFLPTMGPA
WVNMYGSTRNYTLMDEHQDLNEGLGEGVSFRARLLISIAVEILDTTSAEIMSSTEVHMEP
VSNISESATGKMEEFFLFGSFLEATMIDRKIGDKPISFEVTIGNYGNQIDGVSKPALAKK
KKEGGGESEEEESELIHNSSEEEAEDDGDLTSVPSTPPMKPVITDRNYFHLPYFEKKPCI
YIKSWWQDQRRRLYNSNIMDKIADKLEEGLNDVQEIIKTEKAYPERRLRGVLEELSTSCS
RFVTLANKDQNLSGRTKLDRERLKSCMREMESMGQQAKTIRTQVKRNTVRDKLKLVLNFL
QRLRFLADEPQHSIPDVFIWMISNNKRIAYARIPSKDILYSIVDEEMGKDCGKVKAVFLR
LPGKKGFGPAGWTVQAKLEMYLWLGLNKQRKDFLIGLPSGFEENKAVKGIGIQAVPPISL
VYNMKQVFQLRAHMYQARSLFAADTSGLSDPFARVFFSTHSQVTEVLSETLCPTWDQLLV
FDNVELYGEAGELRDDPPIIVIELYDQDTVGKAEFIGRTFAKPLTKMVDEHYGPPRFPPQ
LEYYQIYRGNCAAGDLLAAFELLQIGPAGRAALPPIDGPTDSDRGPILPVPLGIRPVLSR
YRIEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSALIQNYKKNPNFSTLVKWFEVDL
PENELLHPPLNIRVVDCRAFGRYILVGSHAVTTLRKFIYSPPDKTANNWAHTGDIVVNMS
PEPNIKKMDTVVKIEATTDAVVKVDLNEDEKEKEKKKKKKKKGEEVEEEEPDESMLDWWS
KYFASIETMMENLRAQEAAQAEAEEREDLEIAAESAEIKADDFPMKGTKPKEKSKDKKST
KDKKKNNDGTEKRPPKPKVDELMVYNKELESEFGSFEDWLHTFNLYRGKAGDDDDHNVVD
EDRIVGRFKGSLCMYKLPLSEEITREAGFDPNMGMFQSIPHNDPINVLVRIYIIRATDLH
PADINGKADPYIVIKLGKSDIRDKENYISKQLNPVFGKSFDIEATFPMESMLTVAVYDWD
LVGTDDLIGETKIDLENRYYSKHRATCGIASNYSVHGYNVWRDPQKPAQILAKLCKEGKL
DGPHYGPGGRVKVANRIFLGPTEIEDESGLKKQTEEHLALTVLRHWEEIPRVGCKLIPEH
VETRPLLNPDKPGIEQGRIEMWVDMFPMDVPAPGPAIDISPRKPKRYELRVIIWNTDEVI
LEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFVFPFDYLMAEEK
IVISKKESMFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNKFPRGAKTAKQCS
LDMVLKEHELPTISIFKQKRVKGWWPFVAQNENDEFELTGKVEAELHLLTAEEAEKSPVG
LGRNDPEPLEKPNRPDTSLMWFMNPLRSIRYFIWHNYRWLILKALALLLLLLLVGLFLYS
IPGYLVKKLLGA

Region:1-1992
Length:1992aa
Label:Full sequence
Reset:click