Input sequence

Protein name E3 ubiquitin-protein ligase HERC2
Organism Mus musculus Length 4836
Disorder content 17.5% ProS content 7.4%
IDEAL NA UniProt Q4U2R1

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 4836 1-1 2-79 80-94 95-96 97-158 159-189 190-269 270-276 277-319 320-365 366-852 853-868 869-913 914-927 928-977 978-1002 1003-1008 1009-1012 1013-1031 1032-1051 1052-1071 1072-1079 1080-1196 1197-1204 1205-1265 1266-1269 1270-1290 1291-1297 1298-1357 1358-1384 1385-1462 1463-1472 1473-1492 1493-1499 1500-1533 1534-1617 1618-1630 1631-1635 1636-1705 1706-1709 1710-1759 1760-1765 1766-1816 1817-1840 1841-1852 1853-1859 1860-1932 1933-1954 1955-2009 2010-2013 2014-2123 2124-2131 2132-2185 2186-2199 2200-2292 2293-2308 2309-2348 2349-2375 2376-2419 2420-2464 2465-2509 2510-2546 2547-2631 2632-2637 2638-2772 2773-2776 2777-2925 2926-2938 2939-3360 3361-3532 3533-3544 3545-3549 3550-3561 3562-3613 3614-3743 3744-3747 3748-3802 3803-3809 3810-4325 4326-4347 4348-4374 4375-4381 4382-4425 4426-4439 4440-4804 4805-4836 2-79 97-158 190-269 277-319 366-852 869-913 928-977 1003-1008 1013-1031 1052-1071 1080-1196 1205-1265 1270-1290 1298-1357 1385-1462 1473-1492 1500-1533 1618-1630 1636-1705 1710-1759 1766-1816 1841-1852 1860-1932 1955-2009 2014-2123 2132-2185 2200-2292 2309-2348 2376-2419 2465-2509 2547-2631 2638-2772 2777-2925 2939-3360 3533-3544 3550-3561 3614-3743 3748-3802 3810-4325 4348-4374 4382-4425 4440-4804 1-1 80-94 159-189 320-365 853-868 914-927 978-1002 1009-1012 1032-1051 1072-1079 1197-1204 1291-1297 1358-1384 1463-1472 1493-1499 1534-1617 1631-1635 1817-1840 1853-1859 1933-1954 2124-2131 2186-2199 2293-2308 2349-2375 2420-2464 2510-2546 2926-2938 3361-3532 3562-3613 3803-3809 4326-4347 4375-4381 4426-4439 4805-4836 159-166 324-365 853-868 926-927 984-1002 1009-1012 1358-1366 1493-1499 1534-1556 1567-1575 1604-1617 1631-1635 1817-1824 2124-2131 2186-2193 2296-2301 2369-2375 2460-2464 2510-2515 2926-2938 3376-3413 3525-3532 3562-3572 3579-3607 4326-4347 4375-4381 4426-4429 4805-4806 4820-4836 3955-4320 2962-3327 423-785 1206-1297 4470-4787 1871-1929 2652-2769 2555-2631 423-785 3955-4320 2962-3327 1206-1297 4424-4790 2642-2775 2564-2630 1868-1930 2762-2914 4523-4787 2555-2632 1871-1933 3277-3324 4270-4317 571-621 677-725 4112-4162 3225-3273 4060-4105 4218-4262 3119-3169 3067-3115 3954-3999 2804-2912 2706-2746 514-567 570-621 624-673 676-725 1210-1284 1871-1933 2703-2747 3011-3063 3066-3115 3118-3169 3172-3221 3224-3273 3276-3325 4059-4108 4165-4214 4217-4266 4269-4318 4489-4792 4398-4788 2994-3326 3953-4271 425-730 2555-2631 2775-2914 1862-1929 1205-1288 2686-2757 3605-3711 2448-2506 410-777 1205-1291 2730-2914 2946-3327 3591-3711 3940-4325 4422-4790 73-87 164-175 198-212 272-281 304-317 521-531 631-645 854-866 902-913 958-977 1052-1066 1310-1316 1440-1446 1545-1563 1939-1952 2211-2222 2381-2388 2402-2416 2521-2540 3179-3190 3357-3365 3430-3447 3480-3495 3755-3771 4008-4024 4172-4186 4808-4828 950-977 3kciA(1-366) 0.0 99.73% 3kciA(2-366) 2e-121 56.28% 4l1mA(1-358) 0.0 96.69% 2keoA(1-92) 3e-42 91.3% 1nd7A(55-370) 1e-31 30.79% 3dkmA(16-73) 8e-17 67.8% 4xi6A(13-139) 9e-10 29.92% 2jngA(2-75) 2e-08 38.96% 4l1mA(1-358) 4e-82 96.69% 3kciA(1-366) 1e-59 99.73% 3kciA(2-366) 2e-48 56.01% 2keoA(1-92) 1e-27 91.3% 1c4zA(5-350) 2e-27 19.52% 4xi6A(8-145) 3e-16 27.97% 2jufA(1-64) 4e-15 37.31% 3dkmA(13-74) 7e-14 63.49% 1jhjA(9-161) 2e-10 26.42% PF00632(26-288) 3e-48 39.7% PF11515(1-77) 7e-27 67.95% PF06701(1-63) 9e-17 57.14% PF00415(1-48) 8e-10 54.17% PF00415(1-48) 1e-09 58.33% PF00415(1-49) 2e-08 54.9% PF00415(1-49) 6e-08 55.1% PF00415(1-49) 1e-06 50.98% PF00415(1-49) 5e-06 48.98% PF00415(1-46) 5e-06 45.65% PF00415(1-45) 1e-05 46.67% PF00415(1-49) 2e-05 47.06% PF00415(1-49) 6e-05 40.82% PF00415(1-47) 0.0009 44.68% PF03256(40-152) 5e-09 35.09% PF00569(3-43) 7e-07 51.22% PF00415 0.00061 23.7% PF00415 7.2e-08 36.7% PF00415 1.3e-08 39.2% PF00415 1.5e-08 39.1% PF00173 3.4e-20 77.7% PF06701 6.8e-41 146.5% PF00569 2e-09 41.9% PF00415 1.4e-06 32.4% PF00415 1.3e-06 32.6% PF00415 6.7e-07 33.5% PF00415 1.2e-10 46.0% PF00415 0.00012 26.0% PF00415 4e-06 31.0% PF00415 1.6e-07 35.6% PF00415 1.7e-07 35.5% PF00415 4.1e-05 27.6% PF00415 2.5e-07 35.0% PF00632 8.1e-67 232.6% 1nd7A(7-371) 1e-77 26.38% 1a12A(48-395) 8e-67 29.13% 1a12A(65-399) 4e-58 23.67% 1a12A(67-399) 5e-50 25.82% 2jngA1(1-74) 1e-30 38.96% 1jhjA(17-161) 1e-17 25.34% 2dk3A1(3-69) 3e-16 60.29% 1awpA(1-83) 1e-12 26.19% 2dipA1(5-74) 7e-12 27.78% 1sfpA(9-108) 2e-08 14.95% 2cpwA1(1-51) 6e-08 25.42% b.69.5 7.9e-85 288.6% d.120.1 1.9e-14 47.1% b.18.1 6.6e-37 122.1% b.69.5 7.4e-99 336.6% b.23.1 0.00061 12.5% b.69.5 7.5e-102 346.8% d.148.1 7.9e-98 293.4%

Sequence

MPSESFCLAAQSRLDSKWLKTDIQLAFTRDGLCGLWNEMVKDGEIVYTGTELAQNRELPL
RKDDGVDAQSGTKKEDLNDKEKKEEEETPAPVYRAKSILESWVWGRQPDVNELKECLSVL
VKEQQALAVQSATTTLSALRLKQRLVILERYFIALNRTVFQENVKVKWKSSSISVPPTEK
KSARPTGRGVEGLARVGSRAALSFAFAFLRRAWRSGEDADLCSELLQESLDALRALPEAS
LFDESTVSSVWLEVVERATRFLRSVVTGDVHGTPGTKGPGGVPLQDQHLALAILLELAVQ
RGTLSQMLSAILLLLQLWDSGAQETDNERSAQGTSAPLLPLLQRFQSIICSKDVPHTESD
MHLLSGPLSPNESFLRYLTLPQDNELAIDLRQTAVVVMAHLDRLATPCMPPLCSSPTSHK
GSLQEVIGWGLIGWKYYANVIGPIQCEGLASLGVMQVACAEKRFLILSRNGRVYTQAYNS
DMLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPK
VISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAG
LKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDV
IKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGST
HCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSSC
SEWSIGLRVPFVVDICSMTFEQLDLLLRQVSEGMDGTADWPPPQEKECMAVATLNLLRLQ
LHAAISHQVDPEFLGLGLGSVLLNSLKQTVVTLASSAGVLSTVQSAAQAVLQSGWSVLLP
TAEERARALSALLPCTVSGNEVNISPGRRFMIDLLVGSLMADGGLESALNAAITAEIQDI
EAKKEAQKEKEIDEQEASASTFHRSRTPLDKDLINTGIYESSGKQCLPLVQLIQQLLRNI
ASQTVARLKDVARRISSCLDFEQQSCERSASLDLLLRFQRLLISKLYPGEKIGPISDTSS
PELMGVGSLLKKYTALVCTHIGDILPVAASIASSSWQHFAEVACVMEGDFTGVLLPELVV
SIVLLLSKNASLMQEAGAIPLLGGLLEHLDRFNHLAPGKERDDHEELAWPGIMESFFTGQ
NCRNNEEVTLIRKADLENHNKDGGFWTVIDGKVYGIKDFQTQSLTGNSILAQFAGEDPVV
ALEAALQFEDTQESMHAFCVGQYLEPDQEVVTIPDLGSLSSPLIDTERNLGLLLGLHASY
LAMSTPLSPVEVECAKWLQSSIFSGGLQTSQIHYSYNEEKDEDHCSSPGGTPISKSRLCS
HRWALGDHSQAFLQAIADNNIQDYNVKDFLCQIERYCRQCHLTTPITFPPEHPVEEVGRL
LLCCLLKHEDLGHVALSLVHVGTLGIEQVKHRTLPKSVVDVCRVVYQAKCSLIKTHQEQG
RSYKEVCAPVIERLRFLFNELRPAVCSDLSIMSKFKLLGSLPRWRRIAQKIIRERRKKRV
PKKPESIDSEEKIGNEESDLEEACVLPHSPINVDKRPISMKSPKDKWQPLLNTVTGVHKY
KWLKQNVQGLYPQSALLNTIVEFALKEEPVDVEKMRKCLLKQLERAEVRLEGIDTILKLA
AKSFLLPSVQYAMFCGWQRLIPEGIDIGEPLTDCLRDVDLIPPFNRMLLEVTFGKLYAWA
VQNIRSVLMDASARFKELGIQPVPLQTITNENPAGPSLGTIPQARFLLVMLSMLTLQHGA
NNLDLLLNSGTLALTQTALRLIGPTCDSVEDDMNASARGASATVLEETRKETAPVQLPVS
GPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQWDTGSTNSYRMG
KEGKYDLKLVELPVSSQPSAEDSDTEDDSEAEQGERNIHPTAMMLTSVINLLQTLCLSVG
VHADIMQSEATKTLCGLLRMLVESGTTDKPAPPDRLVAREQHRSWCTLGFVRSIALTPQA
CGALSSPRWITLLMKVVEGHAPFTAASLQRQILAVHLLQAVLPSWDKTERARDMKCLVEK
LFGFLGSLLTTCSSDVPLLRESTLRKRRARPQASLTATHSSTLAEEVVGLLRTLHSLTQW
NGLINKYINSQLCSVTQSYAGKTSERAQLEDYFPDSENLEVGGLMAVLAVIGGIDGRLRL
GGQVMHDEFGEGTVTRITPKGRITVQFCDMRMCRVCPLNQLKPLPAVAFSVNNLPFTEPM
LSVWAELVNLAGSKLEKHKTKKSAKPAFAGQVDLDLLRSQQLKLYILKAGRALLSHQDKL
RQILSQPAVQGTGTLQTDDGAAASPDLGDMSPEGPQPPMILLQQLLSSATQPSPVKAIFD
KQELEAAALALCQCLAVESTHPSSPGCEDCSSSEATTPVSVQHIHLARAKKRRQSPAPAL
PIVVQLMEMGFPRKNIEFALKSLTGTSGNASGLPGVEALVGWLLDHSDVQVTEFSDAETL
SDEYSDEEVVEDVDDTPYPVAAGAVVTESQTYKKRADFLSNDDYAVYVRENVQVGMMVRC
CRTYEEVCEGDVGKVIKLDRDGLHDLNVQCDWQQKGGTYWVRYIHVELIGYPPPSSSSHI
KIGDKVRVKASVTTPKYKWGSVTHQSVGLVKAFSANGKDIIVDFPQQSHWTGLLSEMELV
PSIHPGVTCDGCQTFPINGSRFKCRNCDDFDFCETCFKTKKHNTRHTFGRINEPGQSAVF
CGRSGKQLKRCHSSQPGMLLDSWSRMVKSLNVSSSVNQASRLIDGSEPCWQSSGSQGKHW
IRLEIFPDVLVHRLKMIVDPADSSYMPSLVVVSGGNSLNNLIELKTININQTDTTVPLLS
DCAEYHRYIEIAIKQCRSSGIDCKIHGLILLGRIRAEEEDLAAVPFLASDNEEEEDDKGS
TGSLIRKKTPGLESTATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAG
GSKSLFAVTVEGKVYSCGEATNGRLGLGMSSGTVPIPRQITALSSYVVKKVAVHSGGRHA
TALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGE
LYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGD
GDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGH
GSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRK
PTLVQGLEGQKITRVACGSSHSVAWTTVDVATPSVHEPVLFQTARDPLGASYLGVPSDAD
SSSSSNKISGANNCKPNRPSLAKILLSLEGNLAKQQALSHILTALQIMYARDAVVGALMP
AGMLAPVECPSFSSSAPASDVSAMASPMHMEDSTLAADLEDRLSPNLWQEKREIVSSEDA
VTPSAVTPSAPSASSRPFIPVTDDPGAASIIAETMTKTKEDVESQNKTSGPEPQSLDEFT
SLLIPDDTRVVVELLKLSVCSRAGDKGREVLSAVLSGMGTAYPQVADMLLELCVTELEDV
ATDSQSGRLSSQPVVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTVM
DGVNRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKDL
LSDRCVLSCPSMDLVTCLLDFRLNLTSNRSIVPRLAASLAACAQLSALAASHRMWALQRL
RRLLTTEFGQSININRLLGENDGESRALSFTGSALAALVKGLPEALQRQFEYEDPIVRGG
KQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRLFL
DEVAKKIRELMADSESMDVLHESHSIFKREQDEQLVQWMNRRPDDWTLSAGGSGTIYGWG
HNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLG
IGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSP
CDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVE
ALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLG
VVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS
LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWST
SKPASAGKLPAQVPMEYNHLQEIPIIALRNRLLLLHHISELFCPCIPMFDLEGSLDETGL
GPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKGGLAGPD
GTKSVFGQMCAKMSSFSPDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEICEELQNGLT
PLLIVTPNGRDESGANRDCYLLNPATRAPVHCSMFRFLGVLLGIAIRTGSPLSLNLAEPV
WKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPSASGQDIQLSSK
HTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSP
DIPLHLLKSVATYKGIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRG
RDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYAR
IALTGEPAADDSSEDSDNEDADSFASDSTQDYLTGH

Region:1-4836
Length:4836aa
Label:Full sequence
Reset:click