Input sequence

Protein name Ryanodine receptor
Organism Drosophila melanogaster Length 5127
Disorder content 15.0% ProS content 5.3%
IDEAL NA UniProt Q24498

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 5127 1-11 12-84 85-91 92-364 365-375 376-460 461-464 465-555 556-559 560-1058 1059-1062 1063-1077 1078-1317 1318-1517 1518-1602 1603-1611 1612-1852 1853-1861 1862-1883 1884-1891 1892-1979 1980-1985 1986-2075 2076-2080 2081-2108 2109-2156 2157-2284 2285-2316 2317-2329 2330-2333 2334-2480 2481-2502 2503-2503 2504-2579 2580-2585 2586-2820 2821-2825 2826-2928 2929-2953 2954-3044 3045-3054 3055-3070 3071-3074 3075-3086 3087-3093 3094-3126 3127-3136 3137-3572 3573-3576 3577-3577 3578-3615 3616-3693 3694-3700 3701-3808 3809-3825 3826-3862 3863-3892 3893-3996 3997-4003 4004-4378 4379-4413 4414-4420 4421-4452 4453-4490 4491-4586 4587-4614 4615-4627 4628-4673 4674-4715 4716-4837 4838-4845 4846-5028 5029-5032 5033-5120 5121-5127 12-84 92-364 376-460 465-555 560-1058 1078-1317 1518-1602 1612-1852 1862-1883 1892-1979 1986-2075 2081-2108 2157-2284 2317-2329 2334-2480 2504-2579 2586-2820 2826-2928 2954-3044 3055-3070 3075-3086 3094-3126 3137-3572 3577-3577 3616-3693 3701-3808 3826-3862 3893-3996 4004-4378 4414-4420 4453-4490 4587-4614 4628-4673 4716-4837 4846-5028 5033-5120 1-11 85-91 365-375 461-464 1063-1077 1318-1517 1603-1611 1853-1861 1884-1891 1980-1985 2109-2156 2285-2316 2481-2502 2929-2953 3045-3054 3071-3074 3087-3093 3127-3136 3573-3576 3578-3615 3809-3825 3863-3892 3997-4003 4379-4413 4421-4452 4491-4586 4615-4627 4674-4715 4838-4845 5029-5032 5121-5127 1-6 461-464 1074-1077 1318-1322 1328-1337 1344-1373 1393-1400 1414-1426 1431-1438 1474-1478 1487-1491 1853-1861 1890-1891 2126-2140 2306-2316 2481-2502 2934-2953 3071-3074 3087-3093 3132-3136 3573-3576 3578-3579 3603-3615 3863-3867 3888-3892 4421-4452 4524-4537 5029-5032 12-533 653-1236 1499-1670 2833-3033 11-533 653-1319 1075-1671 2830-3038 2705-2919 384-888 3743-3768 4197-4261 14-197 4002-4130 2831-2924 853-942 967-1058 2954-3039 444-641 2226-2446 4633-4761 1091-1210 211-392 439-648 663-802 853-946 966-1060 1091-1216 1529-1672 2224-2453 2830-2924 2953-3041 3621-4135 4477-4761 4855-5020 153-294 2647-2729 1079-1206 2851-3037 4207-4262 215-391 4207-4264 318-333 365-375 694-711 2139-2160 2748-2762 3084-3093 3123-3135 3599-3615 3810-3825 3866-3886 4039-4050 4403-4411 4453-4469 4491-4502 4508-4517 4544-4565 4585-4618 4686-4711 4888-4894 4922-4933 4978-4992 4998-5021 5122-5127 4587-4614 4453-4475 4644-4666 4733-4755 4874-4896 4922-4944 5002-5021 4jkqA(1-499) 1e-141 51.8% 4uweA(583-1081) 3e-124 41.88% 4uweA(1038-1178) 1e-22 35.47% 4ervA(3-189) 9e-45 45.27% 4uweA(1-523) 0.0 49.63% 4uweA(583-1150) 0.0 37.94% 4uweA(583-1179) 6e-126 21.34% 4uweA(1792-1973) 4e-117 39.71% 4uweA(1800-1971) 2e-43 21.46% 4uweA(659-1120) 3e-38 16.64% 2bcxB(1-26) 0.0004 50.0% 2fceA(3-66) 0.0008 30.3% PF08709(4-218) 3e-30 41.01% PF08454(1-114) 1e-24 52.71% PF02026(2-95) 1e-23 47.87% PF02026(1-90) 3e-23 53.33% PF02026(2-93) 3e-21 48.91% PF02026(2-93) 1e-20 52.17% PF01365(5-194) 5e-22 38.0% PF01365(2-182) 1e-18 32.3% PF06459(157-270) 4e-17 45.74% PF00622(1-115) 4e-11 36.07% PF02815 4.7e-75 259.9% PF01365 9.8e-98 335.3% PF00622 1.6e-36 131.9% PF02026 2.1e-37 134.8% PF02026 6.7e-45 159.8% PF00622 1.7e-43 155.1% PF00622 6.4e-31 113.3% PF01365 7e-94 322.5% PF02026 2e-36 131.6% PF02026 1.5e-32 118.8% PF08454 5.9e-246 827.6% PF06459 2.1e-137 467.1% PF00520 1.5e-10 45.6% 1t9fA(2-147) 2e-25 16.99% 2i76A1(10-102) 2e-15 12.9% 2fbeA1(50-174) 4e-11 19.08% 1b7eA(14-203) 3e-05 7.77% 1xo5A(101-160) 0.0006 16.67% b.42.6 1e-61 205.5% a.39.1 2.2e-08 26.2%

Sequence

MAEAEGGSEQDDVSFLRTEDMVTLSCTATGERVCLAAEGFGNRHCFLENIADKNVPPDLS
QCVFVIEQALSVRALQELVTAAGSETGKGTGSGHRTLLYGNAILLRHHNSDMYLACLSTS
SSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKE
NEQSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTWGREAG
QNIVIYEGGVVMAQARSLWRLELARTKWTGGFINWYHPMRIRHITTGRYLGVNDSNELIL
VKKEEASIATTTFCLRQEKDDEKKVLEDKDLEVIGSPIIKYGDTTVIVQHCETSLWLSYK
SYETKKKGVGKVEEKQAILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFITALE
TLQSNRRHSIFFQKVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDLFQEE
GVLNLILEAIDKINIITSQGFLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTNCAQF
ANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEKHGRD
PKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLVDHVASIRPNIFVGRVDGS
SMYQKWYFEVTMDHIEQTTHMMPHLRIGWANTSGYVPYPGGGKKWGGNGVGDDLYSFGFD
GAFLWTGGRKTLVVDALPEEPFIRKGDVIGVAIDLSVPIITFTFNGVKVRGSFRDFNLDG
MFFPVMSCSSKLSCRFLFGGDHGRLKFAPPMGFSALVQCLMPQQILSLDPCFYFGNLAKN
VLAGPWLIEDDTAFVPKPVDTTGVTLPSSVDQIKEKLAENIHEMWALNKIEAGWSWGEHR
DDYHRIHPCLTHFEKLPAAEKRYDNQLAVQTLKTIISLGYYITMDKPPARIRPVRLPNEI
FMQGNGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWARERIQQGWTYGLNEDSENHRS
PHLVPYAKVDEAIKKANRDTASETVRTLLVYGYVLDPPTGEGTEALLAEAQRLKFAGFRT
YRVERNYAVTSGKWYFEFEVLTSGPMRVGWARADCYPGAMLGSEDTSWAFDGHNVTKMHA
GSIEHFGVRYEAGDVIGCFIDVKEQTISFSLNGELLMDALGGETTFADVTAEGVGFVPAC
TLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENTEEMP
DCRIDVTRIPGGADTPPHLKISHNTFETMEKANWEFLRLSLPVTCMGEFISEQEKARRWD
EIKNRQYRLMREAEIAAQMQVQTQAAHMDHMLKGGFNMNDIKGLTRNFDEHADAEADHMM
RGPNRPPRKGSLTRNITFETDMSAALDEMQRSTSVLDMNGLGEEMDDKKKRGRSPFKFFS
KKSRDQSREKMGARTLDTSLERRNTVAHGRNVVNQQMTTRAPTLRLNNAEIPPSPVPQGP
KQLSGSNLGQQPVETSGDEMFDAECLKLINEYFYGVRIFPGQDPTHVYVGWVTTQYHLHS
REFNKNKVRRGSVYIEDDYEMAIERIDRQSCYVVRADELFNEVTQDASGKGASQGMFVGC
FVDTATGIIRFTCEGKDTSHRWMMEPDTKLFPAIFVEATSKEILQIELGRTPTTLPLSAA
VLPTSDKHINPQSPPRLKVQCLRPHQWARVPNTALQVHALKLSDVRGWSMLCEDPVSMLA
LHIPEEDRCIDILELIEMDKLLSFHAHSLTLYAALCYQSNYRAAHALCQHVDQKQLLYAI
RSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYITPLGAELKELYSDEEMQHSLRSL
VTESVRPQLRMTEITPPVIATSSMPSVSSEPIPDIDQLYSPKFPLEVVRQFVMEALKDAV
EINQVHNRDPIGWTNENLFLPLIKLTDRLLLVGVLTDEDVQRLLVMIDPETWDQAFEREG
KDEHRKGLLTMKMAEGAKLQMCYLLHHLYDTQLRHRVESIIAFSHDFVGDLQTDQLRRYI
EIKQSDLPSAVAAKKTKEFRCPPREQMNQILCFKNLEPDDQDNCTCGLELRGRLGDFHDS
LMQKVSLNALQEPDGVEGTAIEEVKTGPITKIYNFINTVKELEEGPKEVEEPEKKTPEEV
FRKVLIKTIVSWAEESQIENPKLVREMFSLLLRQYDTVGELVRALEKTYVINTRARDDVA
EMWVGLSQIRALLPVQMSQEEEELMRKRLWKLVNNATFFQHPDLIRILRVHENVMAVMMN
TLGRRAQAQSDAPTQSEVAEGAPSKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFDHFD
FLLDNANILLARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSNSE
LVEKGYPDLGWDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLGPALRGEG
EGLFRAIVEANRMSERISDRCKMQDEAEGTIAGLNFTHPLPEGEEDEDYIDTGAAILNFY
CTLVDLLGRCAPDASVIEQGKNESLRARAILRSLVPLEDLQGVLSLKFTLSQTAPGEEKP
KSDMPSGLLPNNKQSIVLFLERVYGIEAQDLFYRLLEDAFLPDLRTATILDKSDGSESDM
ALAMNRYIGNSILPLLIKHSKFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAVSDF
LVALTSQMQPAMLLKLLRKLTVDVSKLSEYTTVALRLLTLHFDRCAKYYGSTQGQGSYGA
SSDEEKRLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNTDEDYYG
RQMGAPDQPQYMPNPIDTNNVHLDNDLNSLVQKFSEHYHDAWASRRLEGGWTYGDIRSDN
DRKHPRLKPYNMLSEYERERYRDPVRECLKGLLAIGWTVEHSEVEVALNHRGSTRRQSKP
QINEFQNEGSPFNYNPHPVDMSNLTLSREMQNMAERLAENSHDIWAKKKNEELNGCGGVI
HPQLVPYDLLTDKEKKKDRERSQEFLKYMQYQGYKLHKPSKGGAVEEGGATQAAVELRFS
YSLLEKLIQYLDRATINMKLLKPSTTFSRRSSFKTATRDIKFFSKVVLPLMEKYFSTHRN
YFIAIATATNNIGAASLKEKEMVASIFCKLAALLRNRLSAFGPDVRITVRCLQVLVKGID
ARTLTKNCPEFIRTSMLTFFNQTSDDLGNTILNLQDGKYSHLRGTHLKTSTSLGYVNQVV
LPVLTAMFDHLAACDYGSDLLLDEIQVASYKILAALYHLGTDGTLTHDRKYLKTEIERHR
PALGSCLGAYSSCFPVAFLEPHLNKHNQYSLLNRIADHSLEAQDIMVKMESCMPNLETIL
AEVDQFVESDKTYNDAPHIIDVILPLLCAYLPFWWSQGPDNVSPTSGNHVTMVTADHMNP
LLRNVLKMIKKNIGNDNAPWMTRIAAYTQQIIINTSEELLKDPFLPLAERVKKRTENMLH
KEDSMRGFIKSATDDTSQVETQLQEDWNLLVRDIYSFYPLLIKYVDLQRNHWLKDNIPEA
EELYNHVAEIFNIWSKSQYFLKEEQNFISANEIDNMALIMPTATRRSAISEGAPAVGGKV
KKKKKNRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRYLKKMPEYD
VIEFARNQLTLPDKLDPSDEMSWQHYLYSKLGKTEEPVDEQALEKANVNSNEKGKDKTQE
TVDRIVAMAKVLFGLHMIDHPQQQSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHRACN
IFARSYYEQWLQEENVGQEVMVEDLTQTFEDSEKSKKEGEETDSKPDPLTQLVTTFCRGA
MTERSGALQEDLLYMSYAQIAAKSTGKEEEEGGDEEGGEGGEEGEGTSIHEQEMEKQKLL
FHQARLSNRGVAEMVLLHISASKGIPSEMVMTTLNLGIAILRGGNIDIQMGMLNHLKEKK
DVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSEGAAGEKNMHDAEFTCALFRFIQL
TCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKAN
FFKAIEVASQVFNTLTEVIQGPCTLNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQV
DLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLAD
LIESPSFHEVDMKNEGWVTPKDFREKMEQSKNYTPEEMDFLLACCERNHEGKIDYRAFVE
HFHEPSKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGSSKRI
ERVYFEIKDSNIEQWEKPQIRESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASG
LMATDDGGGNVKRDTAYSSYMSEEEEERAARDPIRRTITAVKEGLKFGVHMLSPANIKHQ
IGVMQTKSIPELIVGFFKIIFYIFYYTGYAHFCVVRYIFGILLNLMRGPAPEQEEEPVVE
EETFGRALPPLPLEEPPGTVQAFGLDINKEENGMYKVVVHESPANSSMEEGGESSPEDGA
AASGELVEGEPHQEPISIVDLLGGEAAKKAAQERQEAQKAQEAAMASIEAEAKKSSSAPQ
ETPAVHQIDFSQYTHRAVSFLARNFYNLKYVALVLAFSINFMLLFYKVTSFTEEADSSAE
EELILGSGSGGGADITGSGFGGSGDGGSGDGEMEDEIPELVHVDEDFFYMEHVLRIAACL
HSLVSLAMLIAYYHLKVPLAIFKREKEIARRLEFEGLFIAEQPEDDDFKSHWDKLVISAK
SFPVNYWDKFVKKKVRQKYSETYDFDSISNLLGMEKSTFAAQESEETGIFKYIMNIDWRY
QVWKAGVTFTDNAFLYSLWYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGK
QLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDKKCHDMLTCFVFHLYKGVRAGGG
IGDEIGDPDGDDYEVYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMES
NCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQ
RSWDFFPVGDCFRKQYEDELSGGGGGG

Region:1-5127
Length:5127aa
Label:Full sequence
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