Input sequence

Protein name Histone-lysine N-methyltransferase EZH2
Organism Homo sapiens Length 746
Disorder content 24.7% ProS content 21.3%
IDEAL NA UniProt Q15910

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam RPS-BLAST:SCOP HMMER:SCOP SEG:LCR 0 746 1-9 10-71 72-75 76-186 187-215 216-252 253-265 266-304 305-307 308-316 317-321 322-328 329-338 339-429 430-483 484-504 505-741 742-746 10-71 76-186 216-252 266-304 317-321 329-338 430-483 505-741 1-9 187-215 253-265 308-316 322-328 339-429 484-504 742-746 189-193 200-211 253-265 308-316 322-328 339-401 406-429 484-504 742-746 520-729 40-68 520-729 40-68 39-68 624-726 606-733 612-735 487-728 183-192 238-252 349-366 385-409 4mi0A(1-208) 1e-127 99.05% 2qxvB(1-29) 1e-08 93.1% 4mi0A(1-208) 6e-38 94.76% 2qxvB(1-29) 1e-08 93.1% PF11616(1-30) 6e-09 96.67% PF00856(2-145) 7e-09 28.08% PF00856 1e-53 189.1% 1h3iA2(21-151) 9e-30 27.41% b.85.7 2.7e-66 182.1%

Sequence

MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW
KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF
MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ
YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL
KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH
ATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPN
NSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKM
KPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPA
PAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQ
NFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVS
CKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDK
YMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGE
ELFFDYRYSQADALKYVGIEREMEIP

Region:1-746
Length:746aa
Label:Full sequence
Reset:click