Input sequence

Protein name Ryanodine receptor 3
Organism Homo sapiens Length 4870
Disorder content 12.4% ProS content 5.8%
IDEAL NA UniProt Q15413

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 4870 1-9 10-86 87-96 97-125 126-129 130-373 374-385 386-454 455-464 465-947 948-954 955-1057 1058-1065 1066-1257 1258-1326 1327-1399 1400-1404 1405-1647 1648-1655 1656-1759 1760-1790 1791-1909 1910-1952 1953-2079 2080-2085 2086-2128 2129-2133 2134-2253 2254-2275 2276-2437 2438-2441 2442-2694 2695-2713 2714-2805 2806-2809 2810-2813 2814-2842 2843-2851 2852-2885 2886-2891 2892-3153 3154-3157 3158-3239 3240-3244 3245-3327 3328-3363 3364-3365 3366-3534 3535-3547 3548-3584 3585-3609 3610-3613 3614-3756 3757-3760 3761-3877 3878-3882 3883-4096 4097-4142 4143-4148 4149-4184 4185-4221 4222-4325 4326-4360 4361-4388 4389-4437 4438-4460 4461-4582 4583-4593 4594-4596 4597-4866 4867-4870 10-86 97-125 130-373 386-454 465-947 955-1057 1066-1257 1327-1399 1405-1647 1656-1759 1791-1909 1953-2079 2086-2128 2134-2253 2276-2437 2442-2694 2714-2805 2814-2842 2852-2885 2892-3153 3158-3239 3245-3327 3366-3534 3548-3584 3614-3756 3761-3877 3883-4096 4143-4148 4185-4221 4326-4360 4389-4437 4461-4582 4597-4866 1-9 87-96 374-385 455-464 948-954 1058-1065 1258-1326 1648-1655 1760-1790 1910-1952 2080-2085 2254-2275 2695-2713 2806-2809 2843-2851 2886-2891 3240-3244 3328-3363 3535-3547 3585-3609 4097-4142 4149-4184 4222-4325 4361-4388 4438-4460 4583-4593 4867-4870 374-385 455-464 948-954 1058-1065 1258-1276 1284-1292 1307-1326 1648-1655 1779-1790 1922-1937 2080-2085 2254-2269 2709-2713 2843-2851 2886-2891 3240-3244 3328-3332 3354-3363 3585-3590 3602-3609 4097-4099 4139-4142 4149-4184 4261-4269 4279-4301 4448-4451 4583-4586 4867-4870 10-531 647-1208 1319-1466 2598-2800 3469-3495 647-1466 10-531 2597-2800 2493-2688 3469-3495 3928-3981 4236-4504 14-205 3726-3851 443-635 2021-2172 2598-2688 848-934 963-1052 2715-2800 1084-1203 263-364 216-398 438-642 657-795 848-942 962-1056 1084-1207 1325-1465 2019-2229 2597-2691 2715-2803 3366-3856 3923-3951 4234-4504 4593-4769 160-301 717-1001 2416-2498 3195-3351 2605-2835 1025-1194 1293-1471 3928-3980 220-400 3928-3985 87-99 517-527 695-706 1774-1793 1912-1919 1933-1950 2201-2218 2271-2277 2749-2762 2879-2889 3171-3186 3539-3547 3592-3613 3760-3771 3862-3882 4103-4121 4321-4339 4343-4363 4434-4443 4670-4688 4701-4713 4747-4765 4326-4360 4185-4207 4410-4429 4482-4504 4613-4635 4670-4692 4751-4770 4uweA(1-523) 0.0 69.55% 4uweA(583-1052) 0.0 59.07% 4uweA(1058-1181) 4e-40 56.76% 4ervA(1-194) 5e-96 95.07% 2bcxB(1-27) 7e-07 88.89% 4uweA(583-1181) 0.0 49.39% 4uweA(1-523) 0.0 69.55% 4uweA(1792-1973) 2e-109 56.86% 4uweA(1794-1973) 4e-41 24.88% 2bcxB(1-27) 7e-08 88.89% 2fceA(11-65) 3e-05 27.27% PF06459(3-270) 5e-54 48.01% PF08709(5-219) 2e-29 39.82% PF08454(4-114) 3e-24 52.38% PF01365(5-194) 2e-23 41.12% PF01365(2-152) 6e-17 35.4% PF02026(2-92) 3e-23 52.75% PF02026(1-87) 1e-22 52.87% PF02026(2-91) 1e-21 51.11% PF02026(1-92) 3e-13 45.65% PF00622(1-117) 2e-06 30.95% PF02815(31-130) 0.0001 29.36% PF02815 2.2e-79 274.3% PF01365 2.3e-95 327.4% PF00622 8.5e-36 129.5% PF02026 1.3e-53 188.7% PF02026 7.3e-54 189.5% PF00622 3.8e-39 140.6% PF00622 2.9e-38 137.7% PF01365 9.3e-78 268.9% PF02026 1.5e-49 175.2% PF02026 6.6e-34 123.2% PF08454 4.1e-256 861.4% PF00036 0.00016 25.6% PF06459 1.1e-132 451.4% PF00520 2e-08 38.6% 1t9fA(2-149) 1e-35 20.26% 1a8iA(235-525) 3e-27 13.92% 2i76A1(10-102) 8e-22 12.9% 1ak6A(21-172) 5e-16 10.91% 1b7eA(1-239) 3e-15 8.79% 2fbeA1(14-171) 3e-15 14.37% 2fbeA1(16-182) 2e-07 10.87% 1ij5A(178-230) 2e-06 28.3% b.42.6 5.6e-73 242.9% a.39.1 2.2e-09 29.4%

Sequence

MAEGGEGGEDEIQFLRTEDEVVLQCIATIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYIP
PDLCVCNFVLEQSLSVRALQEMLANTGENGGEGAAQGGGHRTLLYGHAVLLRHSFSGMYL
TCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSER
YLHLSVSNGNIQVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVVRLFHGHDECLTIPSTD
QNDSQHRRIFYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTED
QGLILQDRAKSDTKSTAFSFRASKELKEKLDSSHKRDIEGMGVPEIKYGDSVCFVQHIAS
GLWVTYKAQDAKTSRLGPLKRKVILHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQ
FVSGNNRTAAPITLPIEEVLQTLQDLIAYFQPPEEEMRHEDKQNKLRSLKNRQNLFKEEG
MLALVLNCIDRLNVYNSVAHFAGIAREESGMAWKEILNLLYKLLAALIRGNRNNCAQFSN
NLDWLISKLDRLESSSGILEVLHCILTESPEALNLIAEGHIKSIISLLDKHGRNHKVLDI
LCSLCLCNGVAVRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKW
YFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLW
SGRIPRAVASINQHLLRSDDVVSCCLDLGVPSISFRINGQPVQGMFENFNTDGLFFPVMS
FSAGVKVRFLMGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRDADGIRDLLGT
TQFLSQASFIPCPVDTSQVILPPHLEKIRDRLAENIHELWGMNKIELGWTFGKIRDDNKR
QHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEEDLKKVKLPKNYMMS
NGYKPAPLDLSDVKLLPPQEILVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLV
PYALLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADSAVEKVSIDKIRFFRVERSY
AVRSGKWYFEFEVVTGGDMRVGWARPGCRPDVELGADDQAFVFEGNRGQRWHQGSGYFGR
TWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADYEIENGFVPICCLGLSQIGR
MNLGTDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPHIEVMRID
GTMDSPPCLKVTHKTFGTQNSNADMIYCRLSMPVECHSSFSHSPCLDSEAFQKRKQMQEI
LSHTTTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLNKNCTVTVTLGDERGRVHE
SVKRSNCYMVWGGDIVASSQRSNRSNVDLEIGCLVDLAMGMLSFSANGKELGTCYQVEPN
TKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFRSEEKNPVPQCPPRLDVQTIQPVLW
SRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMRFHYH
TLRLYSAVCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLASAKE
RKLMMKNEYIIPITSTTRNIRLFPDESKRHGLPGVGLRTCLKPGFRFSTPCFVVTGEDHQ
KQSPEIPLESLRTKALSMLTEAVQCSGAHIRDPVGGSVEFQFVPVLKLIGTLLVMGVFDD
DDVRQILLLIDPSVFGEHSAGTEEGAEKEEVTQVEEKAVEAGEKAGKEAPVKGLLQTRLP
ESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQANQKFRYNELMQALNMSAALTA
RKTKEFRSPPQEQINMLLNFQLGENCPCPEEIREELYDFHEDLLLHCGVPLEEEEEEEED
TSWTGKLCALVYKIKGPPKPEKEQPTEEEERCPTTLKELISQTMICWAQEDQIQDSELVR
MMFNLLRRQYDSIGELLQALRKTYTISHTSVSDTINLLAALGQIRSLLSVRMGKEEELLM
INGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGTEKSQIAFPKMVASCCRFLCYF
CRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALSLEEPDLE
KVVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKL
LIRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQGYKREVSTGDDEEEEEIVH
MGNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLP
SLNKDGSVSEPDMAANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASASLD
TVSLSTTEAALALNRYICSAVLPLLTRCAPLFAGTEHCTSLIDSTLQTIYRLSKGRSLTK
AQRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLTNHYEQCWKYYCL
PSGWGSYGLAVEEELHLTEKLFWGIFDSLSHKKYDPDLFRMALPCLSAIAGALPPDYLDT
RITATLEKQISVDADGNFDPKPINTMNFSLPEKLEYIVTKYAEHSHDKWACDKSQSGWKY
GISLDENVKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAVGWTVERTKEGEALVQQRE
NEKLRSVSQANQGNSYSPAPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKLELESKGG
GSHPLLVPYDTLTAKEKFKDREKAQDLFKFLQVNGIIVSRGMKDMELDASSMEKRFAYKF
LKKILKYVDSAQEFIAHLEAIVSSGKTEKSPRDQEIKFFAKVLLPLVDQYFTSHCLYFLS
SPLKPLSSSGYASHKEKEMVAGLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTLDTRT
VMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALLPI
LTSIFEHVTQHQFGMDLLLGDVQISCYHILCSLYSLGTGKNIYVERQRPALGECLASLAA
AIPVAFLEPTLNRYNPLSVFNTKTPRERSILGMPDTVEDMCPDIPQLEGLMKEINDLAES
GARYTEMPHVIEVILPMLCNYLSYWWERGPENLPPSTGPCCTKVTSEHLSLILGNILKII
NNNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAVKTVQEEEQLKADG
KGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKSPDADSDQLFRMVAEVFI
LWCKSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKAMQVKSGGQDQERKKTKRRGDLY
SIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKSRYSHRDTDEEVREHLRNNLHLQEKS
DDPAVKWQLNLYKDVLKSEEPFNPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKLLS
KQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEEYSFEEKLVQDLAKSPKVEE
EEEEETEKQPDPLHQIILYFSRNALTERSKLEDDPLYTSYSSMMAKSCQSGEDEEEDEDK
EKTFEEKEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGN
AGVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRE
RGEKVLQNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVDYLLRLQES
ISDFYWYYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAV
VGFLHVFANMQMKLSQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLV
ESSTNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGIISKKEFQKAMEGQKQYTQSEID
FLLSCAEADENDMFNYVDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAES
VLNYFEPYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQE
KMELFVNFCEDTIFEMQLASQISESDSADRPEEEEEDEDSSYVLEIAGEEEEDGSLEPAS
AFAMACASVKRNVTDFLKRATLKNLRKQYRNVKKMTAKELVKVLFSFFWMLFVGLFQLLF
TILGGIFQILWSTVFGGGLVEGAKNIRVTKILGDMPDPTQFGIHDDTMEAERAEVMEPGI
TTELVHFIKGEKGDTDIMSDLFGLHPKKEGSLKHGPEVGLGDLSEIIGKDEPPTLESTVQ
KKRKAQAAEMKAANEAEGKVESEKADMEDGEKEDKDKEEEQAEYLWTEVTKKKKRRCGQK
VEKPEAFTANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEE
ETEDVANLWNSFNDEEEEEAMVFFVLQESTGYMAPTLRALAIIHTIISLVCVVGYYCLKV
PLVVFKREKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVIN
KYGDLYGAERIAELLGLDKNALDFSPVEETKAEAASLVSWLSSIDMKYHIWKLGVVFTDN
SFLYLAWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVV
VYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGD
PYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDY
FDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDC
FRKQYEDQLG

Region:1-4870
Length:4870aa
Label:Full sequence
Reset:click