Input sequence

Protein name Rho guanine nucleotide exchange factor 6
Organism Homo sapiens Length 776
Disorder content 34.0% ProS content 17.7%
IDEAL NA UniProt Q15052

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 776 1-4 5-91 92-157 158-220 221-237 238-548 549-711 712-762 763-776 5-91 158-220 238-548 712-762 1-4 92-157 221-237 549-711 763-776 92-132 151-157 549-552 577-580 589-595 624-629 653-711 763-767 773-776 229-437 4-111 430-551 158-222 712-761 229-437 2-115 430-551 159-223 712-761 246-417 164-214 4-93 2-111 163-217 245-420 450-548 229-436 131-225 4-124 430-548 1-133 142-236 229-432 423-547 552-572 590-606 689-700 718-759 1by1A(1-209) 1e-80 66.51% 1wyrA(8-115) 2e-57 100.0% 1v61A(8-130) 4e-56 84.55% 1ujyA(6-70) 3e-33 98.46% 2w6bA(2-50) 3e-12 70.0% 1by1A(1-209) 2e-42 66.51% 1wyrA(6-119) 1e-35 95.61% 1v61A(8-130) 4e-35 84.55% 1ujyA(7-71) 3e-29 98.46% 2w6bA(2-50) 6e-11 70.0% PF00621(2-176) 2e-21 34.66% PF07653(1-51) 4e-09 50.98% PF00307(4-89) 0.0005 30.43% PF00307 2.3e-18 71.6% PF00018 4.7e-22 83.9% PF00621 2.2e-17 68.3% PF00169 1.4e-16 65.6% 1by1A(1-208) 1e-37 66.83% 1udlA(4-97) 7e-18 33.68% 1ujoA(11-135) 7e-16 22.83% 1v61A(8-126) 1e-07 85.71% a.40.1 2.3e-26 86.2% b.34.2 2.5e-22 79.4% a.87.1 9.8e-48 160.9% b.55.1 6.6e-36 126.1%

Sequence

MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKN
YYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLC
QALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQG
ASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQD
LRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIM
LSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWL
EQLNRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPL
RPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQIL
KVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYA
LKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP

Region:1-776
Length:776aa
Label:Full sequence
Reset:click