Input sequence

Protein name Histone-lysine N-methyltransferase SETDB1
Organism Homo sapiens Length 1291
Disorder content 45.7% ProS content 24.1%
IDEAL NA UniProt Q15047

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 1291 1-32 33-110 111-191 192-404 405-547 548-863 864-1197 1198-1291 33-110 192-404 548-863 1198-1291 1-32 111-191 405-547 864-1197 5-32 124-139 168-172 179-184 418-438 484-496 503-511 864-877 882-895 906-937 946-951 978-1018 1032-1035 1046-1085 1097-1101 1132-1183 1193-1197 196-397 681-864 1165-1290 192-397 680-832 1200-1266 602-690 682-795 1201-1265 594-668 681-795 797-1273 689-871 1204-1281 586-658 250-313 257-315 594-671 663-1282 108-118 121-131 447-469 528-549 896-915 953-967 1100-1115 37-64 3dlmA(7-208) 1e-118 100.0% 2o8jA(6-177) 3e-25 34.59% 2r3aA(135-269) 4e-16 37.23% 3dlmA(3-208) 1e-76 98.54% 3bo5A(4-139) 5e-24 32.03% 4nj5A(416-482) 5e-20 35.82% 5agqA(12-100) 1e-11 20.22% PF05033(2-103) 2e-18 47.83% PF00856(87-145) 2e-06 46.15% PF01429 3e-25 94.5% PF05033 1.3e-49 175.4% PF00856 4.2e-71 246.8% 1ml9A(2-187) 2e-31 28.95% 1ml9A(187-260) 2e-17 30.77% 1ub1A(11-85) 6e-13 21.33% 2hqxA1(18-76) 0.0007 17.19% b.34.9 5e-05 17.9% d.10.1 4.4e-15 54.2% b.85.7 5.4e-91 250.6%

Sequence

MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQL
AQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPS
ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
FADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEE
SNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVP
PSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRME
AEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKT
SMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSGS
EGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQF
YDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTE
LTWDYNYEVGSVEGKELLCCCGAIECRGRLL

Region:1-1291
Length:1291aa
Label:Full sequence
Reset:click