Input sequence

Protein name Voltage-dependent L-type calcium channel subunit alpha-1C
Organism Homo sapiens Length 2221
Disorder content 34.3% ProS content 19.8%
IDEAL NA UniProt Q13936

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 2221 1-99 100-216 217-219 220-228 229-447 448-501 502-776 777-869 870-1354 1355-1357 1358-1366 1367-1681 1682-1687 1688-2117 2118-2154 2155-2221 100-216 229-447 502-776 870-1354 1367-1681 2118-2154 1-99 220-228 448-501 777-869 1358-1366 1688-2117 2155-2221 1-22 52-61 70-74 82-88 448-470 485-501 777-788 800-828 835-843 853-869 1688-1723 1743-1757 1774-1778 1811-1832 1845-1885 1897-1911 1918-1943 1949-1957 1981-1986 2001-2021 2044-2064 2075-2084 2102-2112 2155-2168 2175-2195 2206-2221 1608-1682 419-447 47-68 1607-1682 1525-1634 412-454 162-404 1273-1523 566-751 957-1149 1658-1685 161-404 558-752 955-1185 1273-1523 1598-1747 1235-1323 521-630 120-242 1287-1406 111-413 503-777 900-953 956-1194 1228-1527 1524-1684 26-39 504-518 635-648 650-668 767-777 798-809 838-857 905-917 994-1003 1013-1027 1162-1181 1812-1822 2027-2042 2084-2093 749-776 125-147 162-184 193-212 268-290 350-372 382-404 524-543 563-585 651-673 723-745 896-918 931-953 958-980 995-1017 1049-1071 1165-1187 1232-1254 1269-1291 1303-1320 1407-1426 1501-1523 3g43E(2-68) 6e-28 88.0% 4deyB(1-29) 7e-10 100.0% 2lqcB(3-24) 0.0002 100.0% 3g43E(1-68) 1e-20 86.84% 2kavA(1-106) 4e-17 24.32% 4dexB(1-43) 4e-11 46.51% PF00520(2-198) 5e-35 37.45% PF00520(1-198) 3e-28 29.73% PF00520(9-197) 2e-18 39.8% PF00520(3-172) 2e-14 36.22% PF08763(1-28) 2e-09 92.86% PF00520 4.2e-76 263.4% PF00520 7.2e-61 212.8% PF00520 8e-70 242.6% PF00520 5.2e-75 259.8% 2ffjA1(27-177) 7e-23 17.2% 1orsC(2-90) 8e-19 6.67% 1orsC(3-108) 2e-11 17.12% 1orsC(2-109) 4e-09 15.45% 2e9xC1(1-84) 2e-13 8.33% f.14.1 4.4e-37 128.8% f.14.1 3.1e-31 108.5% f.14.1 0.00013 15.9% f.14.1 7.9e-27 93.2% f.14.1 4.4e-34 118.4% a.39.1 0.00057 13.3%

Sequence

MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
SNRERHVPMCEDLELRRDSGSAGTQAHCLLLRKANPSRCHSRESQAAMAGQEETSQDETY
EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA
SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA
TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM
VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA
ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS
L

Region:1-2221
Length:2221aa
Label:Full sequence
Reset:click