Input sequence

Protein name Voltage-dependent L-type calcium channel subunit alpha-1S
Organism Homo sapiens Length 1873
Disorder content 25.1% ProS content 13.2%
IDEAL NA UniProt Q13698

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 1873 1-25 26-145 146-156 157-367 368-405 406-684 685-768 769-1207 1208-1214 1215-1227 1228-1340 1341-1345 1346-1539 1540-1785 1786-1824 1825-1873 26-145 157-367 406-684 769-1207 1228-1340 1346-1539 1786-1824 1-25 146-156 368-405 685-768 1215-1227 1341-1345 1540-1785 1825-1873 9-20 368-379 397-405 685-685 710-723 732-743 751-768 1341-1345 1555-1565 1571-1578 1599-1627 1659-1668 1695-1762 1772-1776 1825-1835 1841-1848 1859-1873 1465-1539 348-374 1464-1539 1382-1491 341-380 89-333 1152-1380 470-659 835-1026 1515-1542 88-333 466-660 834-1064 1152-1380 1114-1201 427-538 47-192 1455-1593 660-737 1166-1267 343-470 50-342 364-685 752-1073 1105-1384 1381-1541 544-576 675-685 740-756 804-818 892-906 1043-1055 1210-1220 1654-1685 1844-1858 657-684 52-74 89-111 123-145 196-218 279-301 311-333 433-451 466-488 559-581 631-653 795-817 837-859 871-893 925-947 1044-1066 1111-1133 1153-1172 1263-1285 1358-1380 3g43E(2-68) 6e-26 82.67% 4deyB(1-27) 7e-06 77.78% 3g43E(1-68) 2e-19 81.58% 2kavA(1-106) 1e-16 24.32% 4dexB(1-40) 8e-08 37.5% PF00520(2-198) 1e-34 35.92% PF00520(1-198) 2e-30 32.49% PF00520(5-197) 4e-17 34.17% PF00520(2-170) 5e-17 33.85% PF08763(1-28) 3e-07 78.57% PF00520 8.4e-73 252.4% PF00520 1.6e-58 205.0% PF00520 6.3e-68 236.3% PF00520 2.4e-70 244.3% 1orsC(2-89) 2e-15 7.87% 1orsC(1-108) 1e-11 18.42% 1orsC(2-125) 4e-07 13.7% 2ffjA1(27-166) 2e-14 14.29% 2clyB1(6-78) 1e-11 24.39% 2e9xC1(1-86) 8e-11 10.78% 1j1jA(4-144) 1e-06 9.93% f.14.1 6.5e-32 110.9% f.14.1 1.2e-32 113.4% f.14.1 2.7e-31 108.7% f.14.1 1e-32 113.7% a.39.1 0.0001 15.9%

Sequence

MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
EPSPCARTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLD
EDLRGYMSWITQGEVMDVEDFREGKLSLDEGGSDTESLYEIAGLNKIIQFIRHWRQWNRI
FRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTTEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSTMAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFDIGFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDL
SKMTEEECRGYYYVYKDGDPMQIELRHREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YKAIDSNAEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLVINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDIVQIQAGLR
TIEEEAAPEICRTVSGDLAAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPP
VMANQRPLQFAEIEMEEMESPVFLEDFPQDPRTNPLARANTNNANANVAYGNSNHSNSHV
FSSVHYEREFPEETETPATRGRALGQPCRVLGPHSKPCVEMLKGLLTQRAMPRGQAPPAP
CQCPRVESSMPEDRKSSTPGSLHEETPHSRSTRENTSRCSAPATALLIQKALVRGGLGTL
AADANFIMATGQALADACQMEPEEVEIMATELLKGREAPEGMASSLGCLNLGSSLGSLDQ
HQGSQETLIPPRL

Region:1-1873
Length:1873aa
Label:Full sequence
Reset:click