Input sequence

Protein name Rho guanine nucleotide exchange factor 5
Organism Homo sapiens Length 1597
Disorder content 73.1% ProS content 37.5%
IDEAL NA UniProt Q12774

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 1597 1-1093 1094-1099 1100-1148 1149-1385 1386-1411 1412-1453 1454-1460 1461-1496 1497-1501 1502-1597 1094-1099 1149-1385 1412-1453 1461-1496 1502-1597 1-1093 1100-1148 1386-1411 14-76 87-102 110-137 142-156 179-192 201-213 220-258 263-270 276-320 327-343 361-368 379-389 398-407 413-432 453-460 470-493 508-517 539-546 560-567 572-583 598-611 616-621 638-658 668-675 689-702 718-733 748-756 779-793 806-813 835-840 882-900 922-933 1007-1011 1034-1047 1069-1074 1080-1093 1100-1118 1386-1401 1168-1430 1513-1572 1167-1503 1513-1572 1181-1356 1516-1562 1178-1357 1391-1502 1514-1569 1167-1371 1313-1438 1512-1580 1384-1497 1150-1377 1365-1497 1506-1582 206-222 225-237 268-280 315-325 510-523 724-730 812-826 838-856 858-868 901-920 1338-1365 1ki1B(3-263) 5e-16 23.4% 1x6bA(18-76) 5e-11 53.33% 4xh9A(9-331) 1e-42 20.12% 1x6bA(18-76) 3e-12 46.67% PF00621(4-178) 2e-18 30.68% PF00018(1-46) 4e-06 46.81% PF00621 1.8e-17 68.6% PF00169 2.5e-09 41.6% PF07653 2.9e-10 44.7% 1ki1B1(2-208) 8e-39 23.08% 1hulA(2-108) 4e-14 10.32% 2iteA1(15-82) 8e-09 8.7% 1ntyA2(6-113) 7e-05 14.91% a.87.1 1.7e-51 179.4% b.55.1 2.6e-19 65.2% b.34.2 7.8e-17 56.3%

Sequence

MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQ
QSELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLA
PPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQT
RYYSPCEEHPAETNQNEGSESGTIRQGEELPPEELQESQGLLHPQEVQVLEEQGQQEAGF
RGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGL
NDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQE
DHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEENEHHGPSMPALIAPEDSPHCD
LFPGASYLMTQIPGTQTESRAEELSPAALSPSLEPIRCSHQPISLLGSFLTEESPDKEID
QNSQQEESRLRKGTVSSQGTEVVFASASVTPPRTPDSAPPSPAEAYPITPASVSARPPVA
FPRRETSCAARAPETASAPLSMDDPSPCGTSEMCPAALYGFPSTGTSPPRPPANSTGTVQ
HLRSDSFPGSHRTEQTPDLVGMLLSYSHSELPQRPPKPAIYSSVTPRRDRRSGRDYSTVS
ASPTALSTLKQDSQESISNLERPSSPPSIQPWVSPHNPAFATESPAYGSSPSFVSMEDVR
IHEPLPPPPPQRRDTHPSVVETDGHARVVVPTLKQHSHPPPLALGSGLHAPHKGPLPQAS
DPAVARQHRPLPSTPDSSHHAQATPRWRYNKPLPPTPDLPQPHLPPISAPGSSRIYRPLP
PLPIIDPPTEPPPLPPKSRGRSRSTRGGHMNSGGHAKTRPACQDWTVPLPASAGRTSWPP
ATARSTESFTSTSRSKSEVSPGMAFSNMTNFLCPSSPTTPWTPELQGPTSKDEAGVSEHP
EAPAREPLRRTTPQQGASGPGRSPVGQARQPEKPSHLHLEKASSWPHRRDSGRPPGDSSG
QAVAPSEGANKHKGWSRQGLRRPSILPEGSSDSRGPAVEKHPGPSDTVVFREKKPKEVMG
GFSRRCSKLINSSQLLYQEYSDVVLNKEIQSQQRLESLSETPGPSSPRQPRKALVSSESY
LQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEVKFELIVSEASYLRSLNIAVDHF
QLSTSLRATLSNQEHQWLFSRLQDVRDVSATFLSDLEENFENNIFSFQVCDVVLNHAPDF
RRVYLPYVTNQTYQERTFQSLMNSNSNFREVLEKLESDPVCQRLSLKSFLILPFQRITRL
KLLLQNILKRTQPGSSEEAEATKAHHALEQLIRDCNNNVQSMRRTEELIYLSQKIEFECK
IFPLISQSRWLVKSGELTALEFSASPGLRRKLNTRPVHLHLFNDCLLLSRPREGSRFLVF
DHAPFSSIRGEKCEMKLHGPHKNLFRLFLRQNTQGAQAEFLFRTETQSEKLRWISALAMP
REELDLLECYNSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGERGW
FPVQQVEFISNPEVRAQNLKEAHRVKTAKLQLVEQQA

Region:1-1597
Length:1597aa
Label:Full sequence
Reset:click