Input sequence

Protein name Tight junction protein ZO-1
Organism Homo sapiens Length 1748
Disorder content 65.0% ProS content 23.1%
IDEAL NA UniProt Q07157

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 1748 1-8 9-113 114-223 224-259 260-418 419-529 530-534 535-585 586-620 621-676 677-682 683-809 810-1627 1628-1748 9-113 224-259 419-529 535-585 621-676 683-809 1628-1748 1-8 114-223 260-418 586-620 677-682 810-1627 6-8 114-117 131-136 157-160 181-223 260-278 287-291 334-349 396-401 415-418 586-591 615-620 677-682 810-835 843-854 860-862 871-882 910-915 1005-1016 1056-1062 1112-1116 1143-1146 1165-1172 1263-1319 1324-1328 1335-1349 1359-1367 1394-1399 1417-1421 1448-1452 1462-1467 1494-1515 1524-1556 1585-1594 1603-1609 421-802 1631-1748 18-110 185-262 421-802 1631-1748 18-110 185-262 1638-1718 433-498 33-106 23-107 186-261 423-501 520-582 1632-1734 636-800 20-108 178-272 420-524 11-121 155-277 403-520 465-636 636-806 1-17 140-151 300-324 605-618 810-824 893-906 1238-1257 1327-1338 1389-1400 1421-1441 3shwA(1-335) 0.0 87.7% 2kxrA(1-118) 7e-64 98.31% 2h2bA(5-97) 5e-48 100.0% 2rczA(2-79) 1e-35 98.72% 3shwA(1-335) 2e-91 87.7% 2kxrA(1-118) 6e-41 98.31% 2h2bA(5-97) 2e-28 100.0% 2rczA(2-79) 1e-27 98.72% PF00791(6-84) 4e-20 62.96% PF00595(12-79) 0.0003 40.0% PF00595(11-81) 0.001 33.33% PF00595 3.6e-24 90.9% PF00595 2.5e-21 81.5% PF00595 3.7e-22 84.2% PF07653 1.7e-13 55.4% PF00791 2.6e-61 214.3% 1jxmA2(1-193) 4e-19 23.86% 1ihjA(3-93) 3e-17 24.18% 1be9A(5-102) 4e-11 17.0% 1be9A(9-115) 5e-11 36.7% b.36.1 4.2e-26 84.0% b.36.1 4.6e-22 73.0% b.36.1 8.1e-27 91.0% b.34.2 5e-11 34.5% c.37.1 6.9e-30 104.5%

Sequence

MSARAAAAKSTAMEETAIWEQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVL
KGGPAEGQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSRPD
PEPVSDNEEDSYDEEIHDPRSGRSGVVNRRSEKIWPRDRSASRERSLSPRSDRRSVASSQ
PAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENM
SLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANASERDDISEIQSLASDHS
GRSHDRPPRRSRSRSPDQRSEPSDHSRHSPQQPSNGSLRSRDEERISKPGAVSTPVKHAD
DHTPKTVEEVTVERNEKQTPSLPEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRP
SMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIR
EEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESPYGLSFNKG
EVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYTLPKTAGGDRAD
FWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFLRPVTIFGPIADVAREK
LAREEPDIYQIAKSEPRDAGTDQRSSGIIRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQ
WYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMND
GWYGALKEAIQQQQNQLVWVSEGKADGATSDDLDLHDDRLSYLSAPGSEYSMYSTDSRHT
SDYEDTDTEGGAYTDQELDETLNDEVGTPPESAITRSSEPVREDSSGMHHENQTYPPYSP
QAQPQPIHRIDSPGFKPASQQKAEASSPVPYLSPETNPASSTSAVNHNVNLTNVRLEEPT
PAPSTSYSPQADSLRTPSTEAAHIMLRDQEPSLSSHVDPTKVYRKDPYPEEMMRQNHVLK
QPAVSHPGHRPDKEPNLTYEPQLPYVEKQASRDLEQPTYRYESSSYTDQFSRNYEHRLRY
EDRVPMYEEQWSYYDDKQPYPSRPPFDNQHSQDLDSRQHPEESSERGYFPRFEEPAPLSY
DSRPRYEQAPRASALRHEEQPAPGYDTHGRLRPEAQPHPSAGPKPAESKQYFEQYSRSYE
QVPPQGFTSRAGHFEPLHGAAAVPPLIPSSQHKPEALPSNTKPLPPPPTQTEEEEDPAMK
PQSVLTRVKMFENKRSASLETKKDVNDTGSFKPPEVASKPSGAPIIGPKPTSQNQFSEHD
KTLYRIPEPQKPQLKPPEDIVRSNHYDPEEDEEYYRKQLSYFDRRSFENKPPAHIAASHL
SEPAKPAHSQNQSNFSSYSSKGKPPEADGVDRSFGEKRYEPIQATPPPPPLPSQYAQPSQ
PVTSASLHIHSKGAHGEGNSVSLDFQNSLVSKPDPPPSQNKPATFRPPNREDTAQAAFYP
QKSFPDKAPVNGTEQTQKTVTPAYNRFTPKPYTSSARPFERKFESPKFNHNLLPSETAHK
PDLSSKTPTSPKTLVKSHSLAQPPEFDSGVETFSIHAEKPKYQINNISTVPKAIPVSPSA
VEEDEDEDGHTVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNS
ILPPLDKEKGETLLSPLVMCGPHGLKFLKPVELRLPHCDPKTWQNKCLPGDPNYLVGANC
VSVLIDHF

Region:1-1748
Length:1748aa
Label:Full sequence
Reset:click