Input sequence

Protein name DNA topoisomerase 2-beta
Organism Homo sapiens Length 1626
Disorder content 31.6% ProS content 4.7%
IDEAL IID00462 UniProt Q02880

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 1626 1-54 55-447 448-454 455-638 639-642 643-1110 1111-1139 1140-1202 1203-1626 55-447 455-638 643-1110 1140-1202 1-54 448-454 1111-1139 1203-1626 11-29 50-54 1111-1115 1203-1208 1234-1247 1332-1335 1368-1373 1602-1612 1620-1626 457-1206 50-426 50-1205 734-1057 333-402 97-245 291-451 734-1201 1508-1611 452-1206 288-437 50-285 50-286 276-438 452-1208 5-19 1109-1121 1129-1142 1213-1227 1248-1269 1299-1311 1336-1348 1376-1395 1531-1549 1563-1576 3qx3A(1-671) 0.0 88.67% 1zxmA(1-373) 0.0 81.7% 4gfhA(1-1100) 0.0 47.16% PF00521(1-333) 1e-30 30.84% PF00204(48-119) 2e-05 37.5% PF02518 2.3e-13 55.0% PF00204 1e-53 189.1% PF00521 1.7e-136 464.0% PF08070 1e-59 209.0% 1bgwA(1-678) 5e-144 40.08% 1pvgA1(2-138) 4e-49 42.67% 1pvgA2(1-238) 2e-47 55.04% d.122.1 1.2e-64 215.9% d.14.1 2.2e-45 146.8% e.11.1 1.8e-263 835.1%

Sequence

MAKSGGCGAGAGVGGGNGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQ
LEHILLRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRD
KNMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVT
GGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITF
QPDLSKFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKL
DETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIE
VVKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFF
KAASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLIL
TEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYK
KSYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVK
ASKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFR
YAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFI
NKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHH
GEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFP
AVDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRM
LDGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQV
LEPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNS
MVLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKI
QGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSG
PDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVE
SQEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKK
KKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGTRVRKTPTS
SGKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDD
DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKK
SQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPS
SDTVPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNP
GRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEDDV
DFAMFN

Region:1-1626
Length:1626aa
Label:Full sequence
Reset:click