Input sequence

Protein name Voltage-dependent L-type calcium channel subunit alpha-1D
Organism Homo sapiens Length 2161
Disorder content 33.5% ProS content 18.0%
IDEAL NA UniProt Q01668

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 2161 1-100 101-219 220-223 224-229 230-452 453-495 496-789 790-856 857-1295 1296-1309 1310-1534 1535-1539 1540-1624 1625-2055 2056-2097 2098-2161 101-219 230-452 496-789 857-1295 1310-1534 1540-1624 2056-2097 1-100 224-229 453-495 790-856 1296-1309 1625-2055 2098-2161 1-11 33-40 50-59 453-454 471-495 792-813 840-856 1625-1663 1679-1692 1724-1729 1755-1761 1773-1796 1803-1836 1845-1882 1887-1892 1901-1912 1920-1946 1978-1990 1995-2007 2040-2055 2098-2109 2117-2133 2146-2161 1548-1622 420-448 1547-1622 1465-1574 413-448 164-405 1239-1463 561-750 922-1113 1598-1625 163-405 557-751 921-1151 1239-1463 1538-1655 1201-1333 520-629 122-267 882-976 75-414 509-776 816-1160 1192-1467 1464-1624 1-10 54-67 451-460 503-517 635-646 649-667 766-781 819-840 979-993 1128-1142 1380-1388 1664-1677 1738-1744 1902-1913 2139-2150 748-789 130-149 164-186 199-218 272-294 351-373 383-405 519-541 561-583 650-672 726-748 882-904 924-946 953-972 1015-1037 1131-1153 1198-1220 1240-1259 1349-1368 1441-1463 3g43E(2-68) 8e-27 82.67% 4deyB(1-29) 7e-10 100.0% 3g43E(1-68) 6e-20 81.58% 2kavA(1-106) 1e-17 25.23% 4dexB(1-36) 1e-09 50.0% PF00520(2-198) 4e-34 38.02% PF00520(1-198) 5e-25 30.47% PF00520(5-197) 3e-18 37.19% PF00520(2-170) 1e-16 34.34% PF08763(1-28) 8e-10 96.43% PF00520 2.7e-72 250.8% PF00520 2.5e-61 214.3% PF00520 2.6e-68 237.6% PF00520 1.8e-74 258.0% 2ffjA1(27-148) 3e-19 15.32% 1orsC(2-115) 5e-16 8.21% 1orsC(3-108) 2e-11 14.41% 1orsC(2-125) 7e-10 13.7% 1orsC(2-91) 1e-05 9.47% f.14.1 5.1e-37 128.6% f.14.1 4.1e-32 111.5% f.14.1 2.3e-33 115.9% f.14.1 1.7e-34 119.8% a.39.1 0.0003 14.3%

Sequence

MMMMMMMKKMQHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRNTSMPTSETESVNTENVS
GEGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTI
SSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIT
ETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLF
IIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGG
PSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARK
ESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPPCDVPVGEEEEEEEEDEPEVP
AGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSS
AALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDM
LVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMI
VTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNS
DFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVA
FFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWY
VVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFK
PKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENVPVPTATPGNSEESNRISITFFRL
FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDN
NQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFA
IVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRI
KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKI
KTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFK
KRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETKREEEDDVFK
RNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNH
HNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHVSENGHHSSHKHDREPQRRSS
VKRTRYYETYIRSDSGDEQLPTICREDPEIHGYFRDPHCLGEQEYFSSEECYEDDSSPTW
SRQNYGYYSRYPGRNIDSERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLLPPTPASHRR
SSFNFECLRRQSSQEEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRS
WATPPATPPYRDWTPCYTPLIQVEQSEALDQVNGSLPSLHRSSWYTDEPDISYRTFTPAS
LTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEME
SAASTLLNGNVRPRANGDVGPLSHRQDYELQDFGPGYSDEEPDPGRDEEDLADEMICITT
L

Region:1-2161
Length:2161aa
Label:Full sequence
Reset:click