Input sequence

Protein name Polycystin-1
Organism Homo sapiens Length 4303
Disorder content 10.5% ProS content 7.0%
IDEAL NA UniProt P98161

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 4303 1-34 35-398 399-403 404-473 474-479 480-498 499-503 504-554 555-566 567-569 570-626 627-638 639-2578 2579-2582 2583-2625 2626-2632 2633-2728 2729-2745 2746-2748 2749-2812 2813-2818 2819-2880 2881-2884 2885-2888 2889-2893 2894-3303 3304-3308 3309-3351 3352-3461 3462-3468 3469-3555 3556-3636 3637-3659 3660-3923 3924-3936 3937-4010 4011-4014 4015-4147 4148-4209 4210-4242 4243-4303 35-398 404-473 480-498 504-554 570-626 639-2578 2583-2625 2633-2728 2749-2812 2819-2880 2894-3303 3309-3351 3462-3468 3556-3636 3660-3923 3937-4010 4015-4147 4210-4242 1-34 399-403 555-566 627-638 2626-2632 2729-2745 2885-2888 3352-3461 3469-3555 3637-3659 3924-3936 4011-4014 4148-4209 4243-4303 6-34 399-403 555-560 627-638 3367-3373 3379-3461 3469-3520 3543-3555 3637-3659 3924-3936 4011-4014 4153-4161 4173-4178 4201-4209 4243-4251 4277-4282 4290-4303 275-354 72-170 403-531 275-354 1136-1208 72-177 3117-3228 403-531 1521-1882 2226-2578 3744-3927 3120-3230 32-66 152-177 180-261 277-352 425-532 743-817 937-1013 1024-1122 1131-1208 1217-1291 1301-1376 1385-1462 1471-1544 1553-1628 1637-1714 1723-1798 1807-1883 1892-1967 1976-2057 2066-2141 2168-2693 3011-3060 3118-3235 3711-4113 3118-3224 49-167 406-531 1088-1195 275-354 1658-1807 1159-1282 1558-1730 1999-2128 1238-1388 50-170 275-354 405-531 938-1022 1026-1124 1132-1210 1218-1300 1299-1378 1376-1471 1481-1553 1554-1637 1714-1807 1809-1892 2065-2145 3119-3224 2-48 238-264 335-347 763-774 781-795 999-1013 1287-1299 1447-1458 1499-1508 2132-2143 2211-2225 2430-2439 2661-2670 2889-2899 3235-3253 3323-3339 3365-3384 3555-3579 3583-3603 3633-3649 3671-3686 3897-3909 3935-3954 3981-4006 4022-4044 4089-4103 4248-4269 3073-3095 3283-3302 3322-3344 3556-3578 3588-3610 3671-3690 3895-3917 3937-3959 3979-4000 4026-4048 1b4rA(1-80) 3e-31 100.0% 2wfhA(80-175) 7e-11 36.36% 1sl4A(2-126) 2e-05 28.46% 1b4rA(1-80) 6e-24 100.0% 1b4rA(8-78) 3e-08 36.49% 3b2dA(500-601) 1e-23 32.08% 3vf1A(1-118) 5e-20 26.05% 1sl4A(2-126) 3e-14 20.93% 3b43A(169-566) 2e-10 13.17% PF02010(33-361) 4e-39 35.85% PF08016(8-176) 6e-23 37.84% PF01477(3-115) 6e-15 40.71% PF01462 2.4e-06 31.7% PF01463 0.00039 24.3% PF01822 8.4e-22 83.0% PF00801 1.8e-12 52.1% PF00059 2.6e-06 26.0% PF00801 0.00029 24.8% PF00801 7.7e-14 56.6% PF00801 2.6e-14 58.2% PF00801 5.1e-22 83.8% PF00801 4.4e-14 57.4% PF00801 8.4e-14 56.5% PF00801 4.3e-18 70.7% PF00801 1.2e-20 79.2% PF00801 6.3e-21 80.1% PF00801 7.1e-20 76.6% PF00801 1.8e-18 72.0% PF00801 3.9e-19 74.2% PF00801 1e-18 72.7% PF00801 6.9e-11 46.8% PF00801 1.2e-22 85.8% PF02010 3.3e-291 978.0% PF01825 1.1e-16 66.0% PF01477 8.2e-27 99.7% PF08016 1.3e-187 633.9% 1ca1A2(7-117) 7e-26 11.71% 2ifgA3(13-154) 1e-17 25.87% 2afpA(7-126) 2e-12 17.19% 2h3kA1(12-106) 1e-10 5.45% 1b4rA(1-80) 1e-10 100.0% 1pmhX(11-171) 1e-10 8.98% 1pmhX(17-157) 5e-10 9.86% 1pmhX(1-183) 7e-07 10.58% 1pmhX(12-153) 8e-06 6.04% 1pmhX(12-181) 7e-05 8.14% c.10.2 3.3e-22 69.1% b.1.3 4.6e-30 88.7% d.169.1 4.7e-27 74.8% b.1.3 1.6e-05 19.4% b.1.3 2.2e-08 24.6% b.1.3 5.7e-25 73.7% b.1.3 5e-08 27.8% b.1.3 5.7e-09 26.4% b.1.3 5.1e-13 44.6% b.1.3 3.7e-13 45.0% b.1.3 8e-12 40.6% b.1.3 3.6e-13 45.1% b.1.3 2.6e-11 38.8% b.1.3 1.4e-30 90.2% b.12.1 1.7e-28 94.8%

Sequence

MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG
PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI
NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY
VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA
SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV
TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE
LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY
RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP
APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD
AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR
RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC
HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD
AGPGALLHCSPAPGHPGPRAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV
LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT
NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP
WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG
SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ
GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP
SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA
GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA
AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV
EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN
PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV
GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS
YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW
DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV
PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA
QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG
KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA
ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV
PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG
TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR
LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC
EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV
RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS
PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL
MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR
LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE
SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL
TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS
KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC
ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG
HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS
ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA
QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA
ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM
RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS
DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS
DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP
YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR
WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS
HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY
EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW
KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA
ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG
AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA
GQQVLDIDSCLDSSVLDSSFLTFSGLHAEQAFVGQMKSDLFLDDSKSLVCWPSGEGTLSW
PDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEG
VSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTG
LVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASF
LGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEE
ARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRS
EELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSD
YDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLH
NWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLP
LLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAAD
RQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLC
RALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESW
HLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLW
MGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVS
LGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSR
GPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST

Region:1-4303
Length:4303aa
Label:Full sequence
Reset:click