Input sequence

Protein name Nicastrin
Organism Mus musculus Length 708
Disorder content 6.6% ProS content 5.1%
IDEAL NA UniProt P57716

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam RPS-BLAST:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 708 1-25 26-266 267-270 271-588 589-597 598-691 692-695 696-699 700-708 26-266 271-588 598-691 696-699 1-25 589-597 692-695 700-708 6-25 589-597 692-695 706-708 41-661 40-662 274-465 273-498 287-501 267-501 5-21 669-691 4upcA(1-409) 3e-168 59.26% 4r12A(1-573) 2e-118 21.49% PF05450(2-199) 1e-65 67.0% PF05450 7.8e-149 505.0% 1cp7A(88-273) 1e-14 14.42% c.56.5 9.9e-11 32.4%

Sequence

MATTRGGSGPDPGSRGLLLLSFSVVLAGLCGGNSVERKIYIPLNKTAPCVRLLNATHQIG
CQSSISGDTGVIHVVEKEEDLKWVLTDGPNPPYMVLLEGKLFTRDVMEKLKGTTSRIAGL
AVTLAKPNSTSSFSPSVQCPNDGFGIYSNSYGPEFAHCKKTLWNELGNGLAYEDFSFPIF
LLEDENETKVIKQCYQDHNLGQNGSAPSFPLCAMQLFSHMHAVISTATCMRRSFIQSTFS
INPEIVCDPLSDYNVWSMLKPINTSVGLEPDVRVVVAATRLDSRSFFWNVAPGAESAVAS
FVTQLAAAEALHKAPDVTTLSRNVMFVFFQGETFDYIGSSRMVYDMENGKFPVRLENIDS
FVELGQVALRTSLDLWMHTDPMSQKNESVKNQVEDLLATLEKSGAGVPEVVLRRLAQSQA
LPPSSLQRFLRARNISGVVLADHSGSFHNRYYQSIYDTAENINVTYPEWQSPEEDLNFVT
DTAKALANVATVLARALYELAGGTNFSSSIQADPQTVTRLLYGFLVRANNSWFQSILKHD
LRSYLDDRPLQHYIAVSSPTNTTYVVQYALANLTGKATNLTREQCQDPSKVPNESKDLYE
YSWVQGPWNSNRTERLPQCVRSTVRLARALSPAFELSQWSSTEYSTWAESRWKDIQARIF
LIASKELEFITLIVGFSTLVFSLIVTYCINAKADVLFVAPREPGAVSY

Region:1-708
Length:708aa
Label:Full sequence
Reset:click