Input sequence

Protein name Tyrosine-protein kinase JAK3
Organism Homo sapiens Length 1124
Disorder content 7.1% ProS content 3.6%
IDEAL NA UniProt P52333

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 1124 1-22 23-259 260-265 266-486 487-505 506-778 779-811 812-1124 23-259 266-486 506-778 812-1124 1-22 260-265 487-505 779-811 7-15 487-491 779-804 814-1098 513-780 24-489 511-1096 24-491 826-1095 527-777 521-777 822-1095 734-1091 463-770 376-475 24-122 366-541 494-777 807-1115 208-226 257-271 1050-1056 3lxlA(1-281) 3e-157 98.25% 4fvqA(2-273) 2e-84 57.35% 4po6A(1-474) 2e-50 32.92% 4oliA(1-532) 4e-130 45.58% 4po6A(1-475) 3e-115 32.45% PF07714(5-254) 2e-41 41.24% PF07714(7-254) 2e-21 30.04% PF07714 2.3e-63 221.1% PF07714 4e-121 413.0% 1nw1A(8-349) 8e-35 7.65% 1nw1A(25-346) 7e-18 6.69% 1a07A(8-104) 1e-06 20.0% 1wxaA1(3-100) 2e-06 12.0% d.93.1 8.3e-20 66.4% d.144.1 4e-41 132.8% d.144.1 2.8e-68 220.2%

Sequence

MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKA
SGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGL
RKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQR
PGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIM
DLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVD
ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFC
KEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNP
LGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPK
EKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR
HEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQ
EFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGA
DGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFS
GVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSL
ISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESE
AHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL
FTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAP
SPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS

Region:1-1124
Length:1124aa
Label:Full sequence
Reset:click