Input sequence

Protein name Presenilin-2
Organism Homo sapiens Length 448
Disorder content 30.4% ProS content 18.8%
IDEAL NA UniProt P49810

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam SEG:LCR TMHMM:TMhelix 0 448 1-77 78-314 315-366 367-370 371-377 378-448 78-314 367-370 378-448 1-77 315-366 371-377 6-22 31-36 44-49 315-348 353-366 371-377 382-448 298-448 84-438 76-439 174-183 341-365 393-417 88-106 138-160 167-189 204-223 230-247 252-274 287-304 385-407 412-434 2kr6A(110-176) 6e-11 53.73% 2kr6A(1-176) 1e-23 31.64% PF01080(2-372) 2e-103 65.34% PF01080 6.5e-252 847.4%

Sequence

MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
TFGLIFYFSTDNLVRPFMDTLASHQLYI

Region:1-448
Length:448aa
Label:Full sequence
Reset:click