Input sequence

Protein name Presenilin-1
Organism Homo sapiens Length 467
Disorder content 34.3% ProS content 12.4%
IDEAL NA UniProt P49768

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam SEG:LCR TMHMM:TMhelix 0 467 1-72 73-298 299-386 387-467 73-298 387-467 1-72 299-386 9-12 18-22 299-308 328-350 361-366 377-386 292-467 292-467 78-457 70-458 61-72 138-153 166-180 413-435 82-100 132-154 161-183 193-215 224-241 246-268 281-298 404-426 431-453 2kr6A(1-176) 9e-66 74.43% 2kr6A(1-176) 1e-65 74.43% PF01080(2-372) 3e-115 68.56% PF01080 4.4e-269 904.5%

Sequence

MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSR
QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE
DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI
YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY
LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA
VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL
TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI

Region:1-467
Length:467aa
Label:Full sequence
Reset:click