Input sequence

Protein name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Organism Homo sapiens Length 1068
Disorder content 3.5% ProS content 1.6%
IDEAL NA UniProt P42336

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP COILS:coiledCoil 0 1068 1-3 4-310 311-319 320-498 499-523 524-968 969-973 974-1068 4-310 320-498 524-968 974-1068 1-3 311-319 499-523 1-3 315-319 499-507 5-1062 3-1062 524-691 354-452 32-107 804-1006 196-290 31-108 173-292 350-485 519-704 796-1015 522-696 106-287 324-478 699-1064 106-301 330-479 497-696 696-1063 699-729 3hhmA(12-1032) 0.0 96.41% 3hhmA(10-1032) 0.0 96.04% PF00613(4-170) 9e-40 47.02% PF00792(4-106) 2e-21 48.54% PF02192(2-77) 2e-20 63.16% PF00454(4-218) 7e-19 32.43% PF00794(13-98) 3e-18 48.42% PF02192 2e-48 171.5% PF00794 1.8e-50 178.3% PF00792 2e-47 168.1% PF00613 2.3e-112 383.9% PF00454 1.3e-97 334.8% 1e7uA1(17-196) 3e-59 43.09% 1e7uA3(1-154) 5e-52 22.53% 1e7uA2(1-146) 4e-16 24.36% 1e7uA4(4-358) 2e-12 38.59% d.15.1 1.1e-48 165.1% b.7.1 1.6e-48 151.3% a.118.1 7.4e-70 218.0% d.144.1 2.1e-107 354.8%

Sequence

MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
CFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPL
SEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN

Region:1-1068
Length:1068aa
Label:Full sequence
Reset:click