Input sequence

Protein name DNA topoisomerase 2-alpha
Organism Rattus norvegicus Length 1526
Disorder content 27.6% ProS content 5.0%
IDEAL NA UniProt P41516

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 1526 1-30 31-276 277-280 281-421 422-430 431-1085 1086-1118 1119-1181 1182-1526 31-276 281-421 431-1085 1119-1181 1-30 277-280 422-430 1086-1118 1182-1526 1-10 27-30 277-280 422-430 1086-1092 1182-1188 1203-1222 1512-1526 431-1187 28-403 28-1165 711-1087 1431-1519 75-222 268-428 711-1180 1431-1519 429-1165 28-263 265-414 28-263 253-415 429-1187 10-21 332-352 1096-1118 1166-1183 1192-1202 1291-1303 1320-1341 1350-1363 1449-1457 1465-1472 4fm9A(1-727) 0.0 92.07% 1zxmA(1-373) 0.0 92.31% 4gfhA(1-1081) 0.0 47.6% PF00521(1-373) 2e-30 30.79% PF08070(1-94) 7e-05 55.32% PF02518 3.5e-14 57.7% PF00204 2.6e-48 171.1% PF00521 2.3e-160 543.3% PF08070 1.7e-48 171.7% 1bgwA(1-658) 2e-142 41.6% 1pvgA2(1-239) 2e-44 53.56% 1pvgA1(2-138) 2e-40 40.0% d.122.1 1.2e-63 212.6% d.14.1 3e-45 146.3% e.11.1 4.5e-265 840.1%

Sequence

MELSPLQPVNENMLLNKKKNEDGKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQM
WVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTMMRNNLISIWNNG
KGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETA
SREYKKMFKQTWMDNMGRAGDMELKPFSGEDYTCITFQPDLSKFKMQSLDKDIVALMVRR
AYDIAGSTKDVKVFLNGNRLPVKGFRSYVDMYLKDKVDETGNALKVVHEQVNPRWEVCLT
MSEKGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKADQVKNHMWI
FGNAVIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQIQ
LNKKCSAVKHNRIKGIPKLDDANDAGSRNSAECTLILTEGDSAKTLAVSGLGVVGRDKYG
VFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQ
DQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEIAFYSLPEFEEWKSTN
PNHKKWKVKYYKGLGTSTSKEAKEYFANMKRHRIQFKYSGPEDDAAISLAFSKKQVDDRK
EWLTNFMEDRRQRKLLGLPEDYLYGQTTMYLTYNDFINKELILFSNSDNERSIPSMVDGL
KPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLN
LLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPSKDDHTLRFLYDDNQRVEPEWYI
PIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNYKGTIEEL
ASNQYVINGEVAILNSTTIEITELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHT
DTTVKFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDF
FELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRGY
DSDPVKAWKEAQQKVPEEEENEENEESESESTSPAAESGPTFNYLLDMPLWYLTKEKKDE
LCKQRDEKEQELNTLKKKTPSDLWKEDLAAFVEELEVVEAKEKQDEQVGLPGKGVKAKGK
KAQISEVLPSPVGKRVIPQVTMEMRAEAEKKIRRKIKSENVEGTPAEDGAEPGLRQRLEK
RQKREPGTRAKKQTTLPFKPIKKAQKQNPWSDSESDMSSNESNFDVPPREKEPRIAATKA
KFTADLDSDDDFSGLDEKDEDEDFFPLDDTPPKTKMPPKNTKKALKPQKSSTSVDLESDG
KDSVPASPGASAADVPAETEPSKPSSKQTVGVKRTITKGQSLTSTAGTKKRAVPKETKSD
SALNAHVSKKPAPAKAKNSRKRMPSSSDSSDSEFEKAISKGATSKKLKGEERDFHVDLDD
TVAPRAKSGRARKPIKYLEESDDDLF

Region:1-1526
Length:1526aa
Label:Full sequence
Reset:click