Input sequence

Protein name Insulin-degrading enzyme
Organism Rattus norvegicus Length 1019
Disorder content 6.6% ProS content 2.6%
IDEAL NA UniProt P35559

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 1019 1-48 49-540 541-544 545-963 964-966 967-985 986-1019 49-540 545-963 986-1019 1-48 967-985 1-19 33-36 46-48 43-1011 43-1011 77-189 74-212 236-418 706-889 299-526 48-282 765-1005 528-749 51-292 283-481 525-755 753-957 284-298 3cwwA(1-953) 0.0 92.98% 3cwwA(1-953) 0.0 92.98% PF00675(3-113) 3e-20 47.79% PF00675 5.2e-67 233.2% PF05193 4e-35 127.3% PF05193 1.5e-19 75.5% 1q2lA3(13-239) 3e-83 21.4% 1q2lA4(5-236) 9e-73 40.85% 1q2lA2(1-225) 2e-67 23.14% 1q2lA1(1-221) 1e-50 22.42% d.185.1 1.3e-48 169.4% d.185.1 8e-10 35.1% d.185.1 2.1e-21 76.1% d.185.1 1.5e-14 50.8%

Sequence

MRNGLVWLLHPALPSTLHSILGARPPPVKRLCGFPKQIYSTMNNPAIQRIEDHIVKSPED
KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIPGLSHFCEHMLFLGTKK
YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDASCKD
REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVREE
LLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQ
LYKIVPIKDIRNLYVTFPIPDLQQYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
AFRFKDKERPRGYTSKIAGKLHYYPLNGVLTAEYLLEEFRPDLIDMVLDKLRPENVRVAI
VSKSFEGKTDRTEQWYGTQYKQEAIPEDVIQKWQNADLNGKFKLPTKNEFIPTNFEILAL
EKDATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL
KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKITEKMATFEIDKKRFE
IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
SRLHIEALLHGNITKQAALGVMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
RRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKAIEDMTEEAFQKHIQALAIRRLDKPKKL
SAECAKYWGEIISQQYNYDRDNIEVAYLKTLSKDDIIKFYKEMLAVDAPRRHKVSVHVLA
REMDSCPVVGEFPSQNDINLSEAPPLPQPEVIHNMTEFKRGLPLFPLVKPHINFMAAKL

Region:1-1019
Length:1019aa
Label:Full sequence
Reset:click