Input sequence

Protein name DNA topoisomerase 1
Organism Drosophila melanogaster Length 972
Disorder content 43.8% ProS content 4.8%
IDEAL NA UniProt P30189

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 972 1-426 427-972 427-972 1-426 1-32 56-60 356-361 423-426 438-850 901-972 438-869 919-970 656-869 438-652 438-652 655-895 438-653 654-869 901-972 424-653 654-972 34-56 59-99 101-201 237-258 312-329 343-356 362-385 394-406 412-435 470-481 534-555 870-884 533-560 859-911 1a31A(1-414) 9e-162 70.29% 1a31A(384-457) 4e-14 56.96% 1a31A(1-435) 1e-136 67.36% 2b9sB(1-52) 5e-15 50.0% PF01028(3-212) 1e-72 66.98% PF02919(1-215) 1e-71 64.65% PF02919 1.8e-154 523.8% PF01028 4.8e-151 512.4% 1a31A2(1-216) 1e-93 66.2% 1a31A1(1-220) 2e-89 68.64% 1a31A1(168-242) 2e-17 54.67% e.15.1 3.7e-105 357.6% d.163.1 7.8e-94 315.6%

Sequence

MSGDVAAENSIHIQNGGSCEVVQSNGVTTNGHGHHHHHHSSSSSSSKHKSSSKDKHRDRE
REHKSSNSSSSSKEHKSSSRDKDRHKSSSSSSKHRDKDKERDGSSNSHRSGSSSSHKDKD
GSSSSKHKSSSGHHKRSSKDKERRDKDKDRGSSSSSRHKSSSSSRDKERSSSSHKSSSSS
SSSKSKHSSSRHSSSSSSKDHPSYDGVFVKPEPVSQQLMHSGSVDAFQMQQLGSYEAAAA
GTNFNGNGNVAGANYKNGYEESIVDIKKEEESFNNLSQASSCDYSMSQFRADEPPFVVKH
EQSYAEEDSTMNYNDHDDDADEMNDDEEDVPLAMRKRKQEATDRPDGGMDNDDDDDIPLL
ARKKVKKEKIKKESKEKSKKRVKEEPSDDYGNVKPKKKKMKKEPEPAVSPGKRQKAKAKV
EEEEVWRWWEEEKRADGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAA
TFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRK
AASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRI
QASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKG
EKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQ
ADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHK
KEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLA
YNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRDEKKGKQLER
LRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFL
WAVHMADENYRF

Region:1-972
Length:972aa
Label:Full sequence
Reset:click