Input sequence

Protein name Non-receptor tyrosine-protein kinase TYK2
Organism Homo sapiens Length 1187
Disorder content 11.6% ProS content 6.1%
IDEAL NA UniProt P29597

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR 0 1187 1-24 25-130 131-137 138-285 286-329 330-334 335-369 370-552 553-575 576-619 620-624 625-1187 25-130 138-285 330-334 370-552 576-619 625-1187 1-24 131-137 286-329 335-369 553-575 620-624 1-9 286-296 313-329 335-353 557-567 620-624 579-1177 26-566 579-1177 26-566 903-1166 655-866 589-866 897-1169 894-1165 630-865 20-123 142-270 444-609 574-872 882-1169 231-245 1122-1134 4oliA(1-539) 0.0 89.65% 4po6A(1-475) 0.0 87.8% 4oliA(1-539) 6e-180 89.32% 4po6A(1-475) 3e-177 87.43% PF07714(7-251) 9e-39 38.81% PF07714(43-254) 1e-17 32.29% PF07714 9.6e-54 189.1% PF07714 2.9e-124 423.4% 1nw1A(92-349) 5e-32 9.25% 1nw1A(112-352) 3e-13 8.27% 2byeA1(3-103) 5e-11 10.58% 2aehA1(7-123) 2e-06 12.21% d.93.1 5e-10 34.1% d.144.1 1.7e-43 139.8% d.144.1 1.1e-70 227.9%

Sequence

MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI
AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP
AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK
NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR
FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP
TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK
AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV
DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP
YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA
GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR
TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS
LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS
ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA
PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ
LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI
RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII
KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI
HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY
ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC
PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC

Region:1-1187
Length:1187aa
Label:Full sequence
Reset:click