Input sequence

Protein name Tyrosine-protein kinase JAK1
Organism Homo sapiens Length 1154
Disorder content 4.2% ProS content 1.6%
IDEAL NA UniProt P23458

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 1154 1-32 33-135 136-141 142-145 146-174 175-182 183-297 298-300 301-329 330-330 331-559 560-568 569-1154 33-135 146-174 183-297 301-329 331-559 569-1154 1-32 136-141 330-330 560-568 1-8 13-20 560-562 573-1146 56-556 573-1154 35-556 881-1147 586-842 583-845 875-1149 831-1145 532-844 52-131 440-554 142-277 430-603 568-857 864-1147 335-358 970-982 331-361 4oliA(1-528) 2e-173 54.36% 4po6A(27-472) 6e-90 38.84% 4oliA(1-536) 1e-144 53.26% 4po6A(2-472) 1e-137 36.88% PF07714(7-252) 4e-42 38.66% PF07714(4-251) 4e-17 28.73% PF07714 1.8e-78 271.3% PF07714 1.9e-130 444.0% 1nw1A(52-349) 1e-29 8.49% 1nw1A(50-352) 9e-21 7.98% 1wxaA1(24-102) 4e-10 8.75% 1a81A1(8-112) 3e-08 17.39% 2aehA1(1-120) 1e-07 8.82% d.93.1 4.1e-19 64.1% d.144.1 1.8e-47 152.6% d.144.1 3.2e-67 218.5%

Sequence

MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
SFQNLIEGFEALLK

Region:1-1154
Length:1154aa
Label:Full sequence
Reset:click