Input sequence

Protein name Insulin-degrading enzyme
Organism Drosophila melanogaster Length 990
Disorder content 3.6% ProS content 0.4%
IDEAL NA UniProt P22817

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP 0 990 1-18 19-513 514-517 518-937 938-951 952-986 987-990 19-513 518-937 952-986 1-18 938-951 987-990 987-990 25-977 25-977 50-162 47-185 209-391 679-863 262-497 27-259 741-972 501-728 24-265 306-455 500-726 728-931 3cwwA(10-952) 0.0 47.11% 3cwwA(10-952) 0.0 46.9% PF00675(3-113) 4e-16 44.25% PF00675 5.7e-65 226.4% PF05193 9.7e-40 142.6% PF05193 1.5e-22 85.5% 1q2lA3(3-237) 5e-71 23.21% 1q2lA4(11-240) 1e-68 40.77% 1q2lA2(3-225) 2e-57 21.89% 1q2lA1(1-227) 2e-39 21.4% d.185.1 1.3e-46 162.5% d.185.1 0.00017 15.8% d.185.1 6e-23 80.1% d.185.1 1.2e-16 58.2%

Sequence

MTIAESSQKSATRKPDSMEPILRLNNIEKSLQDTRDYRGLQLENGLKVLLISDPNTDVSA
AALSVQVGHMSDPTNLPGLAHFCEHMLFLGTEKYPHENGYTTYLSQSGGSSNAATYPLMT
KYHFHVAPDKLDGALDRFAQFFIAPLFTPSATEREINAVNSEHEKNLPSDLWRIKQVNRH
LAKPDHAYSKFGSGNKTTLSEIPKSKNIDVRDELLKFHKQWYSANIMCLAVIGKESLDEL
EGMVLEKFSEIENKNVKVPGWPRHPYAEERYGQKVKIVPIKDIRSLTISFTTDDLTQFYK
SGPDNYLTHLIGHEGKGSILSELRRLGWCNDLMAGHQNTQNGFGFFDIVVDLTQEGLEHV
DDIVKIVFQYLEMLRKEGPKKWIFDECVKLNEMRFRFKEKEQPENLVTHAVSSMQIFPLE
EVLIAPYLSNEWRPDLIKGLLDELVPSKSRIVIVSQSFEPDCDLAEPYYKTKYGITRVAK
DTVQSWENCELNENLKLALPNSFIPTNFDISDVPADAPKHPTIILDTPILRVWHKQDNQF
NKPKACMTFDMSNPIAYLDPLNCNLNHMMVMLLKDQLNEYLYDAELASLKLSVMGKSCGI
DFTIRGFSDKQVVLLEKLLDHLFDFSIDEKRFDILKEEYVRSLKNFKAEQPYQHSIYYLA
LLLTENAWANMELLDAMELVTYDRVLNFAKEFFQRLHTECFIFGNVTKQQATDIAGRVNT
RLEATNASKLPILARQMLKKREYKLLAGDSYLFEKENEFHKSSCAQLYLQCGAQTDHTNI
MVNLVSQVLSEPCYDCLRTKEQLGYIVFSGVRKVNGANGIRIIVQSAKHPSYVEDRIENF
LQTYLQVIEDMPLDEFERHKEALAVKKLEKPKTIFQQFSQFYGEIAMQTYHFEREEAEVA
ILRKISKADFVDYFKKFIAKDGEERRVLSVHIVSQQTDENATSEAEPVEITNMERHKPIS
DIVTFKSCKELYPIALPFLDIKAKGARSKL

Region:1-990
Length:990aa
Label:Full sequence
Reset:click