Input sequence

Protein name DNA topoisomerase 2
Organism Drosophila melanogaster Length 1447
Disorder content 21.7% ProS content 2.2%
IDEAL NA UniProt P15348

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 1447 1-12 13-406 407-413 414-1073 1074-1117 1118-1196 1197-1447 13-406 414-1073 1118-1196 1-12 407-413 1074-1117 1197-1447 8-12 407-413 1219-1233 1443-1447 9-1183 9-1188 693-1018 57-205 251-410 693-1177 411-1184 247-397 9-246 9-246 236-398 411-1188 323-333 542-553 1077-1107 1235-1278 1299-1318 1332-1347 1374-1396 1413-1424 1426-1444 1169-1196 4gfhA(1-1098) 0.0 46.44% 4gfhA(1-1102) 0.0 45.4% PF00521(1-333) 1e-24 30.23% PF02518 8.7e-14 56.4% PF00204 3e-48 170.9% PF00521 7.5e-75 259.3% 1bgwA(1-676) 1e-126 39.1% 1pvgA1(1-138) 2e-46 42.38% 1pvgA2(1-239) 1e-44 52.3% d.122.1 2.6e-64 214.8% d.14.1 8.7e-48 154.5% e.11.1 1.2e-250 794.2%

Sequence

MENGNKALSIEQMYQKKSQLEHILLRPDSYIGSVEFTKELMWVYDNSQNRMVQKEISFVP
GLYKIFDEILVNAADNKQRDKSMNTIKIDIDPERNMVSVWNNGQGIPVTMHKEQKMYVPT
MIFGHLLTSSNYNDDEKKVTGGRNGYGAKLCNIFSTSFTVETATREYKKSFKQTWGNNMG
KASDVQIKDFNGTDYTRITFSPDLAKFKMDRLDEDIVALMSRRAYDVAASSKGVSVFLNG
NKLGVRNFKDYIDLHIKNTDDDSGPPIKIVHEVANERWEVACCPSDRGFQQVSFVNSIAT
YKGGRHVDHVVDNLIKQLLEVLKKKNKGGINIKPFQVRNHLWVFVNCLIENPTFDSQTKE
NMTLQQKGFGSKCTLSEKFINNMSKSGIVESVLAWAKFKAQNDIAKTGGRKSSKIKGIPK
LEDANEAGGKNSIKCTLILTEGDSAKSLAVSGLGVIGRDLYGVFPLRGKLLNVREANFKQ
LSENAEINNLCKIIGLQYKKKYLTEDDLKTLRYGKVMIMTDQDQDGSHIKGLLINFIHTN
WPELLRLPFLEEFITPIVKATKKNEELSFYSLPEFEEWKNDTANHHTYNIKYYKGLGTST
SKEAKEYFQDMDRHRILFKYDGSVDDESIVMAFSKKHIESRKVWLTNHMDEVKRRKELGL
PERYLYTKGTKSITYADFINLELVLFSNADNERSIPSLVDGLKPGQRKVMFTCFKRNDKR
EVKVAQLSGSVAEMSAYHHGEVSLQMTIVNLAQNFVGANNINLLEPRGQFGTRLSGGKDC
ASARYIFTIMSPLTRLIYHPLDDPLLDYQVDDGQKIEPLWYLPIIPMVLVNGAEGIGTGW
STKISNYNPREIMKNLRKMINGQEPSVMHPWYKNFLGRMEYVSDGRYIQTGNIQILSGNR
LEISELPVGVWTQNYKENVLEPLSNGTEKVKGIISEYREYHTDTTVRFVISFAPGEFERI
HAEEGGFYRVFKLTTTLSTNQMHAFDQNNCLRRFPTAIDILKEYYKLRREYYARRRDFLV
GQLTAQADRLSDQARFILEKCEKKLVVENKQRKAMCDELLKRGYRPDPVKEWQRRIKMED
AEQADEEDEEEEEAAPSVSSKAKKEKEVDPEKAFKKLTDVKKFDYLLGMSMWMLTEEKKN
ELLKQRDTKLSELESLRKKTPEMLWLDDLDALESKLNEVEEKERAEEQGINLKTAKALKG
QKSASAKGRKVKSMGGGAGAGDVFPDPDGEPVEFKITEEIIKKMAAAAKVAQAAKEPKKP
KEPKEPKVKKEPKGKQIKAEPDASGDEVDEFDAMVEGGSKTSPKAKKAVVKKEPGEKKPR
QKKENGGGLKQSKIDFSKAKAKKSDDDVEEVTPRAERPGRRQASKKIDYSSLFSDEEEDG
GNVGSDDDGNASDDDSPKRPAKRGREDESSGGAKKKAPPKKRRAVIESDDDDIEIDEDDD
DDSDFNC

Region:1-1447
Length:1447aa
Label:Full sequence
Reset:click