Input sequence

Protein name Cystic fibrosis transmembrane conductance regulator
Organism Homo sapiens Length 1480
Disorder content 16.6% ProS content 7.9%
IDEAL IID00540 UniProt P13569

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 1480 1-3 4-241 242-248 249-383 384-390 391-419 420-644 645-729 730-771 772-845 846-1174 1175-1184 1185-1443 1444-1480 4-241 249-383 420-644 730-771 846-1174 1185-1443 1-3 242-248 391-419 645-729 772-845 1175-1184 1444-1480 1-3 242-248 391-404 414-419 663-675 701-729 772-784 806-809 841-845 1175-1184 1444-1451 1476-1480 390-670 1202-1430 390-670 1202-1456 123-303 99-300 944-1083 465-574 1251-1374 81-350 451-622 862-1147 1237-1419 1192-1440 432-670 846-1164 68-300 392-635 825-1170 1210-1448 305-322 995-1012 1106-1119 84-106 121-143 196-215 219-241 304-326 859-881 901-923 986-1008 1015-1034 1098-1120 1129-1148 1q3hA(1-265) 2e-124 77.58% 3gd7A(1-229) 2e-122 96.07% 1q3hA(1-265) 2e-108 77.58% 3gd7A(1-256) 5e-94 87.11% 3zdqA(62-243) 2e-05 16.13% PF00664(19-225) 2e-11 27.96% PF00664(72-211) 3e-06 25.17% PF00005(1-121) 2e-08 34.15% PF00005(1-123) 0.0004 28.47% PF00664 3.5e-56 197.3% PF00005 3.4e-54 190.6% PF00664 3e-62 217.4% PF00005 8.5e-60 209.2% 1q3hA(2-238) 7e-29 19.84% 1q3hA(27-265) 7e-29 82.85% 1pf4A2(1-275) 3e-19 12.73% 2hydA2(4-241) 6e-13 15.06% c.37.1 3.9e-55 179.5% f.37.1 1.9e-45 137.0% c.37.1 9.9e-51 166.1%

Sequence

MQRSPLEKASVVSKLFFSWTRPILRKGYRQRLELSDIYQIPSVDSADNLSEKLEREWDRE
LASKKNPKLINALRRCFFWRFMFYGIFLYLGEVTKAVQPLLLGRIIASYDPDNKEERSIA
IYLGIGLCLLFIVRTLLLHPAIFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQL
VSLLSNNLNKFDEGLALAHFVWIAPLQVALLMGLIWELLQASAFCGLGFLIVLALFQAGL
GRMMMKYRDQRAGKISERLVITSEMIENIQSVKAYCWEEAMEKMIENLRQTELKLTRKAA
YVRYFNSSAFFFSGFFVVFLSVLPYALIKGIILRKIFTTISFCIVLRMAVTRQFPWAVQT
WYDSLGAINKIQDFLQKQEYKTLEYNLTTTEVVMENVTAFWEEGFGELFEKAKQNNNNRK
TSNGDDSLFFSNFSLLGTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEG
KIKHSGRISFCSQFSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIV
LGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTR
ILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLQPDFSSKLMGCDSFDQFSAERRNS
ILTETLHRFSLEGDAPVSWTETKKQSFKQTGEFGEKRKNSILNPINSIRKFSIVQKTPLQ
MNGIEEDSDEPLERRLSLVPDSEQGEAILPRISVISTGPTLQARRRQSVLNLMTHSVNQG
QNIHRKTTASTRKVSLAPQANLTELDIYSRRLSQETGLEISEEINEEDLKECFFDDMESI
PAVTTWNTYLRYITVHKSLIFVLIWCLVIFLAEVAASLVVLWLLGNTPLQDKGNSTHSRN
NSYAVIITSTSSYYVFYIYVGVADTLLAMGFFRGLPLVHTLITVSKILHHKMLHSVLQAP
MSTLNTLKAGGILNRFSKDIAILDDLLPLTIFDFIQLLLIVIGAIAVVAVLQPYIFVATV
PVIVAFIMLRAYFLQTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHK
ALNLHTANWFLYLSTLRWFQMRIEMIFVIFFIAVTFISILTTGEGEGRVGIILTLAMNIM
STLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEGKPTKSTKPYKNGQLSKVMIIENSHVKK
DDIWPSGGQMTVKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRL
LNTEGEIQIDGVSWDSITLQQWRKAFGVIPQKVFIFSGTFRKNLDPYEQWSDQEIWKVAD
EVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVT
YQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLLNERSLFRQA
ISPSDRVKLFPHRNSSKCKSKPQIAALKEETEEEVQDTRL

Region:1-1480
Length:1480aa
Label:Full sequence
Reset:click