Input sequence

Protein name DNA topoisomerase 1
Organism Homo sapiens Length 765
Disorder content 27.2% ProS content 6.7%
IDEAL NA UniProt P11387

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 765 1-207 208-642 643-643 644-765 208-642 644-765 1-207 643-643 1-24 40-51 123-126 198-207 643-643 215-628 720-765 215-655 712-763 215-429 433-652 215-429 432-673 215-430 431-655 720-765 692-712 201-430 431-765 20-93 148-209 321-337 666-691 310-337 644-718 1a31A(1-414) 0.0 99.52% 1a31A(413-457) 2e-20 97.83% 1a31A(1-443) 6e-154 93.91% 2b9sB(1-52) 4e-16 48.08% PF02919(1-215) 4e-72 67.91% PF01028(3-217) 2e-69 65.45% PF02919 5.7e-161 545.3% PF01028 2.2e-152 516.8% 1a31A2(1-216) 1e-108 100.0% 1a31A1(1-228) 1e-99 87.72% 1a31A1(197-242) 6e-19 97.83% 1a36A1(52-72) 1e-11 100.0% e.15.1 2.2e-109 372.0% d.163.1 1e-96 325.3%

Sequence

MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKK
HKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEP
EDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKD
KDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKF
YYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKC
DFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGL
FRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENI
QGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALY
FIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNK
VPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQ
QLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLAD
ARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSK
LNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF

Region:1-765
Length:765aa
Label:Full sequence
Reset:click