Input sequence

Protein name Proto-oncogene tyrosine-protein kinase ROS
Organism Homo sapiens Length 2347
Disorder content 6.1% ProS content 3.9%
IDEAL NA UniProt P08922

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR TMHMM:TMhelix 0 2347 1-282 283-289 290-1540 1541-1546 1547-1841 1842-1849 1850-1853 1854-1859 1860-1882 1883-1902 1903-2231 2232-2332 2333-2338 2339-2347 1-282 290-1540 1547-1841 1850-1853 1860-1882 1903-2231 2333-2338 1842-1849 1854-1859 1883-1902 2232-2332 2339-2347 1842-1849 1854-1859 1883-1890 1900-1902 2232-2248 2258-2263 2268-2276 2300-2304 2312-2332 2339-2347 1934-2229 980-1150 102-273 1449-1741 709-883 1934-2229 102-183 1753-1847 1951-2215 194-273 99-183 194-275 1041-1140 1945-2215 1941-2211 180-273 1025-1149 691-865 293-425 1741-1842 558-676 943-1046 102-188 1664-1757 100-190 181-288 290-556 557-675 675-932 964-1049 1040-1149 1153-1440 1453-1534 1553-1655 1647-1757 1751-1851 1930-2235 274-285 2050-2062 1860-1882 3zbfA(1-281) 2e-151 94.93% 4urtB(40-201) 5e-07 25.43% 4pbxA(288-464) 8e-07 25.27% 1fnfA(88-358) 0.0003 22.3% 3s94A(28-204) 0.0004 23.94% 3zbfA(1-281) 4e-117 94.93% 3utoA(6-90) 3e-05 20.93% 3utoA(3-92) 7e-05 19.0% PF07714(7-254) 7e-58 44.74% PF00041(2-83) 7e-07 34.12% PF00041 0.00012 26.0% PF00041 2.6e-10 44.9% PF00041 0.00011 26.1% PF07714 9.6e-151 511.4% 1nw1A(91-349) 6e-40 9.59% 1wfoA1(6-105) 6e-11 21.0% 1wfoA1(5-116) 1e-09 20.0% 1npeA(22-199) 2e-10 17.53% 1npeA(4-138) 6e-06 14.6% 1cn4A1(2-106) 3e-07 11.43% 1gh7A2(6-112) 2e-09 14.88% 1gh7A2(1-114) 6e-05 14.66% 1wisA1(14-109) 1e-07 23.71% 1ujtA(24-120) 2e-07 12.37% b.1.2 3.8e-12 39.5% b.1.2 7.1e-18 63.1% b.68.5 2.9e-25 82.6% b.1.2 4.2e-11 40.3% b.68.5 6.6e-23 74.8% b.1.2 4.2e-07 24.1% b.1.2 9.6e-13 44.6% b.68.5 1.2e-16 54.1% b.1.2 0.00042 13.0% b.1.2 3.9e-08 29.6% b.1.2 8.3e-14 48.9% b.1.2 1.2e-11 41.0% d.144.1 3.2e-80 258.9%

Sequence

MKNIYCLIPKLVNFATLGCLWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHNLSEPCIQG
CHFWNSVDQKNCALKCRESCEVGCSSAEGAYEEEVLENADLPTAPFASSIGSHNMTLRWK
SANFSGVKYIIQWKYAQLLGSWTYTKTVSRPSYVVKPLHPFTEYIFRVVWIFTAQLQLYS
PPSPSYRTHPHGVPETAPLIRNIESSSPDTVEVSWDPPQFPGGPILGYNLRLISKNQKLD
AGTQRTSFQFYSTLPNTIYRFSIAAVNEVGEGPEAESSITTSSSAVQQEEQWLFLSRKTS
LRKRSLKHLVDEAHCLRLDAIYHNITGISVDVHQQIVYFSEGTLIWAKKAANMSDVSDLR
IFYRGSGLISSISIDWLYQRMYFIMDELVCVCDLENCSNIEEITPPSISAPQKIVADSYN
GYVFYLLRDGIYRADLPVPSGRCAEAVRIVESCTLKDFAIKPQAKRIIYFNDTAQVFMST
FLDGSASHLILPRIPFADVKSFACENNDFLVTDGKVIFQQDALSFNEFIVGCDLSHIEEF
GFGNLVIFGSSSQLHPLPGRPQELSVLFGSHQALVQWKPPALAIGANVILISDIIELFEL
GPSAWQNWTYEVKVSTQDPPEVTHIFLNISGTMLNVPELQSAMKYKVSVRASSPKRPGPW
SEPSVGTTLVPASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYS
DTKGDVFVWLLNGTDISENYHLPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTD
IVTHVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLVLQTQPWFSGKKVIALTLDL
SDGLLYWLVQDSQCIHLYTAVLRGQSTGDTTITEFAAWSTSEISQNALMYYSGRLFWING
FRIITTQEIGQKTSVSVLEPARFNQFTIIQTSLKPLPGNFSFTPKVIPDSVQESSFRIEG
NASSFQILWNGPPAVDWGVVFYSVEFSAHSKFLASEQHSLPVFTVEGLEPYALFNLSVTP
YTYWGKGPKTSLSLRAPETVPSAPENPRIFILPSGKCCNKNEVVVEFRWNKPKHENGVLT
KFEIFYNISNQSITNKTCEDWIAVNVTPSVMSFQLEGMSPRCFIAFQVRAFTSKGPGPYA
DVVKSTTSEINPFPHLITLLGNKIVFLDMDQNQVVWTFSAERVISAVCYTADNEMGYYAE
GDSLFLLHLHNRSSSELFQDSLVFDITVITIDWISRHLYFALKESQNGMQVFDVDLEHKV
KYPREVKIHNRNSTIISFSVYPLLSRLYWTEVSNFGYQMFYYSIISHTLHRILQPTATNQ
QNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKAQEIWAMDLEGCQCWRVITVPAML
AGKTLVSLTVDGDLIYWIITAKDSTQIYQAKKGNGAIVSQVKALRSRHILAYSSVMQPFP
DKAFLSLASDTVEPTILNATNTSLTIRLPLAKTNLTWYGITSPTPTYLVYYAEVNDRKNS
SDLKYRILEFQDSIALIEDLQPFSTYMIQIAVKNYYSDPLEHLPPGKEIWGKTKNGVPEA
VQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISHLALIPETPLRQSEFPNGRLTL
LVTRLSGGNIYVLKVLACHSEEMWCTESHPVTVEMFNTPEKPYSLVPENTSLQFNWKAPL
NVNLIRFWVELQKWKYNEFYHVKTSCSQGPAYVCNITNLQPYTSYNVRVVVVYKTGENST
SLPESFKTKAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEIRKSTSNNLQNQN
LRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPET
SFILTIIVGIFLVVTIPLTFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLAN
ACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVK
TLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRK
ARMATFYGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKI
GDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQ
PYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRN
FFLNSIYKSRDEANNSGVINESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATE
CGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHS
GYGDGSD

Region:1-2347
Length:2347aa
Label:Full sequence
Reset:click