Input sequence

Protein name DNA topoisomerase 2
Organism Saccharomyces cerevisiae Length 1428
Disorder content 22.3% ProS content 1.5%
IDEAL NA UniProt P06786

Prediction

Order Disorder ProS BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil 0 1428 1-10 11-260 261-267 268-275 276-414 415-419 420-1066 1067-1108 1109-1173 1174-1428 11-260 276-414 420-1066 1109-1173 1-10 261-267 415-419 1067-1108 1174-1428 7-10 261-262 415-419 1067-1070 1174-1179 7-1177 7-1177 690-1015 55-204 250-418 690-1171 419-1177 7-245 246-406 7-245 235-406 419-1178 326-346 452-465 1086-1100 1126-1149 1184-1195 1266-1272 1321-1345 1380-1392 1402-1416 1119-1153 4gfhA(1-1102) 0.0 94.11% 4gfhA(1-1102) 0.0 93.85% PF00521(1-337) 4e-27 30.84% PF02518 1.4e-15 62.3% PF00204 2.3e-48 171.3% PF00521 3.4e-105 360.1% 1bgwA(1-679) 2e-128 88.14% 1pvgA2(1-239) 1e-50 97.49% 1pvgA1(1-139) 4e-47 80.75% d.122.1 4.1e-70 234.3% d.14.1 2.3e-43 140.2% e.11.1 1.2e-270 857.9%

Sequence

MSTEPVSASDKYQKISQLEHILKRPDTYIGSVETQEQLQWIYDEETDCMIEKNVTIVPGL
FKIFDEILVNAADNKVRDPSMKRIDVNIHAEEHTIEVKNDGKGIPIEIHNKENIYIPEMI
FGHLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTEFILETADLNVGQKYVQKWENNMSIC
HPPKITSYKKGPSYTKVTFKPDLTRFGMKELDNDILGVMRRRVYDINGSVRDINVYLNGK
SLKIRNFKNYVELYLKSLEKKRQLDNGEDGAAKSDIPTILYERINNRWEVAFAVSDISFQ
QISFVNSIATTMGGTHVNYITDQIVKKISEILKKKKKKSVKSFQIKNNMFIFINCLIENP
AFTSQTKEQLTTRVKDFGSRCEIPLEYINKIMKTDLATRMFEIADANEENALKKSDGTRK
SRITNYPKLEDANKAGTKEGYKCTLVLTEGDSALSLAVAGLAVVGRDYYGCYPLRGKMLN
VREASADQILKNAEIQAIKKIMGLQHRKKYEDTKSLRYGHLMIMTDQDHDGSHIKGLIIN
FLESSFPGLLDIQGFLLEFITPIIKVSITKPTKNTIAFYNMPDYEKWREEESHKFTWKQK
YYKGLGTSLAQEVREYFSNLDRHLKIFHSLQGNDKDYIDLAFSKKKADDRKEWLRQYEPG
TVLDPTLKEIPISDFINKELILFSLADNIRSIPNVLDGFKPGQRKVLYGCFKKNLKSELK
VAQLAPYVSECTAYHHGEQSLAQTIIGLAQNFVGSNNIYLLLPNGAFGTRATGGKDAAAA
RYIYTELNKLTRKIFHPADDPLYKYIQEDEKTVEPEWYLPILPMILVNGAEGIGTGWSTY
IPPFNPLEIIKNIRHLMNDEELEQMHPWFRGWTGTIEEIEPLRYRMYGRIEQIGDNVLEI
TELPARTWTSTIKEYLLLGLSGNDKIKPWIKDMEEQHDDNIKFIITLSPEEMAKTRKIGF
YERFKLISPISLMNMVAFDPHGKIKKYNSVNEILSEFYYVRLEYYQKRKDHMSERLQWEV
EKYSFQVKFIKMIIEKELTVTNKPRNAIIQELENLGFPRFNKEGKPYYGSPNDEIAEQIN
DVKGATSDEEDEESSHEDTENVINGPEELYGTYEYLLGMRIWSLTKERYQKLLKQKQEKE
TELENLLKLSAKDIWNTDLKAFEVGYQEFLQRDAEARGGNVPNKGSKTKGKGKRKLVDDE
DYDPSKKNKKSTARKGKKIKLEDKNFERILLEQKLVTKSKAPTKIKKEKTPSVSETKTEE
EENAPSSTSSSSIFDIKKEDKDEGELSKISNKFKKISTIFDKMGSTSATSKENTPEQDDV
ATKKNQTTAKKTAVKPKLAKKPVRKQQKVVELSGESDLEILDSYTDREDSNKDEDDAIPQ
RSRRQRSSRAASVPKKSYVETLELSDDSFIEDDEEENQGSDVSFNEED

Region:1-1428
Length:1428aa
Label:Full sequence
Reset:click